Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 8183349 | Markers of XMRV infection and uses thereof The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an ... | 05/22/2012 |
| 8183250 | Potent PARP inhibitors The present invention relates to 1H-benzimidazole-4-carboxamides of formula (I), their preparation, and their use as inhibitors of the enzyme poly(ADP-ribose)polymerase for the preparation of drugs. ... | 05/22/2012 |
| 8183237 | Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HTreceptor The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for trea... | 05/22/2012 |
| 8183002 | Autoantibody enhanced immunoassays and kits The present disclosure provides immunoassays and kits for detection or quantification of an analyte of interest in a test sample that potentially contains endogenously produced autoantibodies reactive with the analyte. ... | 05/22/2012 |
| 8178548 | Anti-infective agents and uses thereof This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, co... | 05/15/2012 |
| 8178092 | Methods of treating psoriasis by administration of antibodies to the p40 subunit of IL-12 and/or IL-23 The invention provides a method of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23. ... | 05/15/2012 |
| 8173972 | Device for use in normalizing readings on a testing machine An optic module verification device for normalizing between X photon counters, including a verification tray with X verification wells and a modular photon emitter in each verification well. Each photon emitter includes a spring, a Beta source disk, a scintillator d... | 05/08/2012 |
| 8173811 | Apoptosis promoters Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an ant... | 05/08/2012 |
| 8173687 | Compounds as cannabinoid receptor ligands Disclosed herein are cannabinoid receptor ligands of formula (I) wherein Y, X1, X2, X3, R1, and R2 are as defined in the specification. Compositions comprising such com... | 05/08/2012 |
| 8173382 | Assay for cardiac troponin autoantibodies The invention provides among other things methods and kits based on assaying for cardiac troponin autoantibodies, either in conjunction with an assay for cardiac troponin and/or as an independent indicator of cardiac pathology, such as myocarditis, cardiomyopathy, a... | 05/08/2012 |
| 8172860 | Articulating suturing device and method A method for closing an opening in tissue using a suturing device includes inserting at least a portion of a suture through a tissue tract and through a tissue wall. Following inserting at least a portion of the suture, the method includes advancing a first end of t... | 05/08/2012 |
| 8171946 | Probe washing cups and methods The invention provides probe washing cups and methods. A probe washing cup has a washing well and a waste cup. A drying section is disposed between an open end of the probe washing cup and an inlet plane of the washing well. The drying section has a channel that is ... | 05/08/2012 |
| 8168791 | Aminomethyl azaadamantane derivatives and methods of use thereof The invention relates to compounds that are substituted aminomethyl azaadamantane derivatives, compositions comprising such compounds, and methods of using such compounds and compositions. ... | 05/01/2012 |
| 8168784 | Processes to make apoptosis promoters Processes to make compounds, including N-acylsulfonamide apoptosis promoters are disclosed. ... | 05/01/2012 |
| 8168760 | Crystalline anti-human IL-12 antibodies The invention relates to batch crystallization methods for crystallizing an anti-hIL-12 antibody that allows the production of the antibody on an industrial scale, antibody crystals obtained according to the methods, compositions containing the crystals, and methods... | 05/01/2012 |
| 8168165 | Alkylated interleukin-18 compositions Alkylated interleukin-18 (IL-18), compositions comprising alkylated IL-18, kits comprising such compositions, methods of alkylating IL-18, and methods of using compositions comprising alkylated IL-18. ... | 05/01/2012 |
| 8167929 | System and method for delivering a stent to a bifurcated vessel A stent delivery catheter system for accurately positioning a stent in a bifurcated vessel is disclosed. The system includes a catheter having a terminal portion and distal tip that is placed in a main branch of the vessel proximate the bifurcation. A fixed guidewir... | 05/01/2012 |
| 8163916 | Azaadamantane ester and carbamate derivatives and methods of use thereof The invention relates to compounds that are substituted azaadamantane ester and carbamate derivatives, compositions comprising such compounds, and methods of using such compounds and compositions. ... | 04/24/2012 |
| 8163915 | 4-substituted azaadamantane derivatives and methods of use thereof The invention relates to compounds that are 4-substituted azaadamantane derivatives, compositions comprising such compounds, and methods of using such compounds and compositions. ... | 04/24/2012 |
| 8163914 | Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof The invention relates to compounds that are acetamide and carboxamide derivatives of azaadamantane, compositions comprising such compounds, and methods of using such compounds and compositions. ... | 04/24/2012 |
| 8163769 | Antibacterial compounds Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophyl... | 04/24/2012 |
| 8159670 | Method and apparatus for rapidly counting and identifying biological particles in a flow stream A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, and for further reducing the complexity of such a cytometer or analyzer, by utilizing the... | 04/17/2012 |
| 8158663 | Compounds as cannabinoid receptor ligands and uses thereof The present invention relates to thiazolidinylidene containing compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, and X are as defined in the specifica... | 04/17/2012 |
| 8158434 | Method for performing counts within a biologic fluid sample A method for enumerating cellular elements and particulates within a biologic fluid sample is provided. According to one aspect of the invention, the method includes the steps of: a) providing a chamber formed between a first planar member that is transparent and a ... | 04/17/2012 |
| 8153813 | Benzothiazole and benzooxazole derivatives and methods of use Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for us... | 04/10/2012 |
| 8153150 | Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances for treatment of vascular disorder A medical device comprising a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a co... | 04/10/2012 |
| 8152826 | Lancet device A lancet device for obtaining a blood sample from a finger or at an alternate site of a patient. The lancet device includes a body and a lancet, the lancet being movable between a retracted position in which the lancet tip is disposed within the body and an extended... | 04/10/2012 |
| 8148408 | Selective substituted pyridine ligands for neuronal nicotinic receptors The present application describes selective ligands of formula (I) for neuronal nicotinic receptors (NNRs), more specifically for the α4β2 NNR subtype, compositions thereof, and methods of using the same, wherein X, R | 04/03/2012 |
| 8148384 | Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics Compounds of formula I wherein A1, A2, and A3 are as defined herein are inhibitors of PIM kinase. The compounds of formula I are useful for the treatment of diseases such as cancer. ... | 04/03/2012 |
| 8148101 | Method for classifying and counting bacteria in body fluids A method for distinguishing erythroblasts from bacteria by automated hematology analyzers, such as, for example, the CELL-DYN® 4000 automated hematology analyzer and the CELL-DYN® Sapphire™ automated hematology analyzer. Bacterial cells scatter light and fluores... | 04/03/2012 |
| 8143486 | Delta-5 desaturase and uses thereof The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be u... | 03/27/2012 |
| 8143383 | Δ-6 desaturase and uses thereof The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be u... | 03/27/2012 |
| 8143284 | Poly(ADP-ribose)polymerase inhibitors Compounds which inhibit the activity of poly(ADP-ribose)polymerase, compositions containing the compounds and methods of treating diseases using the compounds is disclosed. ... | 03/27/2012 |
| 8142442 | Snare An intravascular snare device for use in capturing debris found in blood vessels. The snare device is fabricated from a tube and includes longitudinally and circumferentially extending members. The snare device specifically embodies structure that provides enhanced ... | 03/27/2012 |
| 8138318 | Hepatitis B pre-S2 nucleic acid This invention relates to a nucleic acid molecule encoding a middle Hepatitis B virus (HBV) surface protein, a vector comprising the nucleic acid molecule, a host cell comprising the vector, and a composition comprising the expression products of this vector, which ... | 03/20/2012 |
| 8137621 | Sample carrier for automatic loading of sample tubes for clinical analyzer A module for staging sample tubes and mixing the samples contained in the sample tubes for an automated clinical analyzer. In one embodiment, this module comprises a mixing drum, which is capable of mixing the contents of a sample tube in an end-over-end manner. The... | 03/20/2012 |
| 8137618 | Blood glucose monitoring kit A blood glucose monitoring kit includes a case constructed in the form of a bi-fold wallet which comprises an upper flap and a lower flap that are connected together through a fold. The case includes an outer layer constructed out of a water resistant and soft fabri... | 03/20/2012 |
| 8137377 | Embolic basket An intravascular basket device for use in capturing either naturally occurring or foreign debris found in blood vessels or other regions of the body. The basket device is fabricated from a tube and includes a mid-section having at least one ring configured in an alt... | 03/20/2012 |
| 8137364 | Articulating suturing device and method Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actua... | 03/20/2012 |
| 8133892 | Compounds that are useful for improving pharmacokinetics Novel compounds of formula 1 or a pharmaceutically acceptable salt thereof inhibit cytochrome P450 monooxygenase. ... | 03/13/2012 |
