|6787562||Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists|
Compounds of the formula I; useful for the treatment of pain wherein A, Z, B, R1, X and D are as defined in the specification, methods of making such compounds, methods of using such compounds and pharmaceutical c...
|6737424||Alpha-substituted pyridazino quinoline compounds|
Alpha-substituted pyridazino-quinoline compounds of formula Ia useful for the treatment of strokes and neurodegenerative disorders: wherein R1 is selected from a variety of substituents including halogen, (C
The present invention relates to carbapenems and provides a compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R2...
An ink comprising water, a water-dissipatable polymer and one or more dyes of Formula (1): ##STR1## wherein: R1 is H or a substituent; R2 and R3 are each independently optionally substituted alkyl, aryl or aralkyl, or R
The present invention relates to particular forms of a novel 1-substituted-N-2-methyl-1-(trifluoroacetyl)propyl!pyrrolidine-2-carboxam ide which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them ...
|5668137||N-heterocyclic sulfonamides having endothelin receptor activity|
The invention concerns pharmaceutically useful compounds of the formula I, in which R1, R2, R3, n, m and Het have any of the meanings defined herein, and their pharmaceutically-acceptable salts, and pharmaceutical composit...
|5632990||Treatment for tumors comprising conjugated antibody A5B7 and a prodrug|
A treatment for tumors to which antibody A5B7 binds is disclosed. A5B7 is a monoclonal antibody which binds to carcinoembryonic antigen. The treatment comprises administering to a host in need of such treatment an effective amount of a system which compri...
The present invention relates to carbapenems and provides a compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R
|5362705||Herbicidal formulations containing n-phosphonomethylglycine and alkyl phenol polyoxyalkylene carboxylic acid surfactant|
Herbicidal compositions contain N-phosphonomethyglycine and alkyl phenol polyoxyalkylene surfactant which contains from about 50 to about 90 weight percent of alkyl phenol polyoxyethylene carboxylic acid....
The invention concerns hydroxylamine derivatives of the formula I ##STR1## wherein R4 is hydrogen, carbamoyl, (1-4C)alkyl, cyclopentyl, cyclohexyl, tetrahydrofuran-3-yl, tetrahydropyran-4-yl, piperidin-4-yl, N-(1-4C)alkylpiperidin-4-yl, (2...
A process for obtaining an isomer of a compound of general formula R--CH(CN)--R' (I) wherein each of R and R' may be any organic radical linked directly or through a heteroatom to the carbon atom bearing the cyano group ...