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| Number | Title | Issue Date |
| 8084058 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative and a disintegrating agent is herein disclosed and described. The dosage form... | 12/27/2011 |
| 7959946 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. ... | 06/14/2011 |
| 7785627 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. ... | 08/31/2010 |
| 7338667 | Pharmaceutical formulation The present invention concerns an extended release formulation having an accelerating erosion and/or dissolution rate of the surface of the formulation. The formulation comprises a drug having low solubility in water dispersed or dissolved in at least one erasable h... | 03/04/2008 |
| 7186706 | Administration of non-oral androgenic steroids to women The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally administering an effective amount of an androgenic steroid. Further, the pres... | 03/06/2007 |
| 7179483 | Compositions and methods for transdermal oxybutynin therapy The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma c... | 02/20/2007 |
| 6866865 | Dosage forms and methods for oral delivery of progesterone Oral progesterone unit dosage forms comprising micronized progesterone and a solid polymeric carrier are provided. The dosage forms, upon oral administration, provide a therapeutically effective blood level of progesterone to a subject. The therapeutically effective... | 03/15/2005 |
| 6743441 | Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma c... | 06/01/2004 |
| 6730318 | Transdermal delivery devices containing polydiorganosiloxane polymers to regulate adhesive properties The adhesive capability of matrix-type transdermal devices for the delivery of drugs, cosmetics, emollients and the like is altered by incorporating into the pressure-sensitive adhesive an effective amount of a polydiorganosiloxane polymer fluid adhesion adjusting a... | 05/04/2004 |
| 6727401 | Pressure sensitive adhesive matrix patch for the treatment of onychomycosis A device for treating antifungal infections of toenails and fingernails is made up of an occlusive backing layer and a pressure sensitive adhesive matrix layer in which is uniformly dispersed an effective amount of an antifungal agent and, optionally, a chemical enh... | 04/27/2004 |
| 6693083 | Conjugates targeted to the interleukin-2 receptor A composition for intracellular delivery of a chemical agent into an interleukin-2-receptor-bearing cell, e.g. an activated T cell, includes a chemical agent and at least one copy of an interleukin-2-receptor-binding and endocytosis-inducing ligand couple... | 02/17/2004 |
| 6630166 | Compositions for conjugated estrogens and associated methods Oral conjugated estrogen formulations are disclosed and described. In one aspect, the oral formulation may be a tablet having a core and one or more coatings thereon. In addition to conjugated estrogen ingredients, the core may include one or more organic... | 10/07/2003 |
| 6585963 | Nail compositions and methods of administering same Nail compositions and methods of use thereof are disclosed. Additionally, nail kits comprising a nail composition and pre-treatment compositions are disclosed. Further, supportive devices such as bandages for use in the administering a nail composition ar... | 07/01/2003 |
| 6583129 | Administration of non-oral androgenic steroids to women The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally administering an effective amount of an androgenic steroid. Furthe... | 06/24/2003 |
| 6544553 | Dosage forms and methods for oral delivery of progesterone Provided is an oral dosage form suitable to deliver a combined dosage of progesterone and which upon delivery through the gastrointestinal tract provides a blood concentration of from about 0.1 ng/ml to about 400 ng/ml progesterone; said dosage form compr... | 04/08/2003 |
| 6365178 | Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions A method of making a pressure sensitive matrix patch for transdermal delivery of a drug is disclosed. The method includes the steps of dissolving a hydrophilic salt form of the drug in the water phase of an aqueous dispersion of a hydrophobic pressure sen... | 04/02/2002 |
| 6210699 | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity A device and method for the oral transmucosal delivery of active substances to the oral cavity utilizing an unplasticized polyvinyl pyrrolidone polymer (PVP) as the primary mucoadhesive. The device is applied and adheres to the mucosa of the oral cavity w... | 04/03/2001 |
| 6180133 | Antioxidant composition for topical/transdermal prevention and treatment of wrinkles An anti-wrinkle skin treating composition comprises a pressure sensitive matrix patch having dissolved in the adhesive a mixture of antioxidants in the form of a Vitamins C ester and Vitamin E. Also preferably dissolved in the adhesive are glycerine and a... | 01/30/2001 |
| 6153223 | Stabilized pharmaceutical compositions The present invention pertains to a stabilized pharmaceutical composition which comprises a mixture of (a) a pharmaceutical agent unstable at a pH above about 3.5; and (b) a stabilizing amount of an acidic pharmaceutically acceptable carrier to stabilize ... | 11/28/2000 |
