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William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Number | Title | Issue Date |
| 5876733 | High molecular weight surface proteins of non-typeable haemophilus High molecular weight surfaces proteins of non-typeable Haemophilus influenzae which exhibit immunogenic properties and genes encoding the same are described. Specifically, genes coding for two immunodominant high molecular weight proteins, HMW1 and HMW2,... | 03/02/1999 |
| 4995882 | Radiolucent breast implant A radiolucent breast implant is comprised of a silicon envelope filled with any biocompatible triglyceride such as peanut oil or sunflower seed oil, or any other material having an effective atomic number of 5.9 which is the effective atomic number of fat... | 02/26/1991 |
| 4855241 | Tumor diagnostic method An in vitro diagnostic method for determining the presence of nerve growth factor receptor bearing tumors is disclosed which comprises determining the presence of an elevated level of a truncated nerve growth factor receptor in a sample of a body fluid fr... | 08/08/1989 |
| 4192020 | Heart valve prosthesis A prosthesis for an inadequate or diseased heart valve, the prosthesis being formed of a porous fabric comprising multifilament synthetic yarns supported on a plural-lobed frame. The frame has generally parallel legs each comprising a pair of rod portions... | 03/11/1980 |
