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Assignee: Wallac Oy


Location: Turku, FI
No. of patents: 81

1      
NumberTitleIssue Date
8158782Biomolecule labeling reactants based on azacycloalkanes and conjugates derived thereof
This invention concerns novel labeling reactants based on azacycloalkanes, wherein a suitable group is linked to the molecule allowing introduction of the said molecules to bioactive molecules in solution or on solid phase. ...
04/17/2012
8143057Chelating agents and highly luminescent and stable chelates and their use
This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relat...
03/27/2012
8071626Chelating agents and highly luminescent and stable chelates and their use
This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relat...
12/06/2011
8012101Punching tool for taking biological samples
The invention relates to a punching tool for taking a biological sample from a filter using punching, the punching tool comprising a punch and a die provided with a punching channel for conveying the sample from the upper surface of the die towards the lower end of ...
09/06/2011
7846658Homogeneous time-resolved energy transfer assay
The invention relates to a method for improving the detection sensitivity in homogenous TR-FRET based bioaffinity assays. The sensitivity is improved by the use of long lifetime donors together with a high energy transfer efficiency and by carrying out the detection...
12/07/2010
7843568Enhanced instrumentation and method for optical measurement of samples
The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by p...
11/30/2010
7776530Integrated nucleic acid analysis
The present invention relates to an integrated method of nucleic acid analysis, and more particularly to a simplified sample pre-treatment, which renders the method more easily automated, where the sample is provided on or applied onto a solid matrix and the subsequ...
08/17/2010
7729582Fibre optic cable and method for producing the same
The present technology relates generally to fibre optic cables their manufacture and uses in the field of optical measurements including biochemical laboratory instrumentation for measuring properties of samples on microtitration plates and corresponding sample supp...
06/01/2010
7544513Hemoglobin assay for neonatal screening
The present invention provides an assay, suitable for neonatal screening of hemoglobinopathies by quantitatively determining the presence of at least one pair of hemoglobin (Hb) variants, determining the ratio between the signals obtained from each variant; and, bas...
06/09/2009
7524458Screen plate of an imaging measuring instrument
Screen plate (10) of an imaging measuring instrument, intended for use in absorption measurement of samples relating to the fields of biochemistry and medicine. The screen plate comprises a plate (11) made of light-absorbing material, such as darkened ...
04/28/2009
7482444Terminating substrates for DNA polymerases
This invention concerns novel terminating substrates for DNA polymerases. The substrates are nucleoside triphosphates labeled with lanthanide chelates. ...
01/27/2009
7381567Dissociative fluorescence enhancement assay
The invention relates to an enhancement solution for an assay technology using lanthanide ions or their chelates as labels and dissociative fluorescence enhancement as a tool for detection, wherein said enhancement solution comprises a β-diketone of formula I
06/03/2008
7381420Labeling reactant
This invention concerns novel labeling reactants suitable for labeling of a biospecific binding reactant using solid-phase synthesis. The novel reactants are derivatives of diethylenetriaminepentaacetic acid (DTPA), wherein a suitable group is linked to the DTPA mol...
06/03/2008
7282581Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof
The invention relates to a labeling reactant of formula (I) useful for labeling an oligonucleotide wherein: R is a temporary protecting group. A is either a phosphorylating moiety or a solid support tethered to Z...
10/16/2007
7211440Dissociative fluorescence enhancement assay
The invention relates to an enhancement solution for an assay technology using lanthanide ions or their chelates as labels and dissociative fluorescence enhancement as a tool for detection, wherein said enhancement solution comprises a β-diketone of formula I
05/01/2007
7205518Method and arrangement for focusing in an optical measurement
A method and arrangement for focus detection in an optical measuring apparatus. The invention is applicable to focus detection for measuring biological or chemical samples or for compiling an image. The position of a focus for an objective lens in a microscope can b...
04/17/2007
7199879Versatile instrumentation for optical measurement of samples
The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by p...
04/03/2007
7192786Biospecific assay method
This invention relates to a biospecific assay method, in which microparticles coated with the bioaffinity reactant A binding the analyte to be assayed; the sample to be analyzed, and the labelled bioaffinity reactant B are mixed. After the binding reaction the signa...
03/20/2007
7068313Method and arrangement for processing measurement data
The invention applies to the binning procedure of data, which is measured with a CCD (Charge-Coupled Device) sensor unit. There is created a solution for measurement of radiation, in which a good signal-to-noise value is achieved, and still it is possible to exploit...
06/27/2006
7023553Intelligent instrumentation with changeable optical components
The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to more reliable, intelligent instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invent...
04/04/2006
6949639Oligonucleotide labeling reactants and their use
The invention relates to a novel labeling reactant of formula (I) suitable for labeling an oligonucleotide wherein: R is a temporary protecting group. A is either a phosphorylating moiety or a solid support t...
09/27/2005
6891618Optical instrument and process for measurement of samples
The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more accurate instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the in...
05/10/2005
6842241Method for checking the operation of an optical measuring device and checking device
A method for checking the operation of a laboratory instrument used in biochemistry by means of an individual test plate (10) by comparing measured values of sample units (20, 21) placed in the wells (12) of the frame plate (11) to previo...
01/11/2005
6841130Pipetting method and multichannel pipetting apparatus
A method and a multichannel pipetting apparatus (40) for simultaneous pipetting of a plurality of sample wells (44) or containers. The pipetting channels (12) of the apparatus have been divided into groups, which are connected via an adapter (
01/11/2005
6784926Method and arrangement for processing CCD pixel data
This invention relates generally to the processing of measured data. Especially the invention applies to the binning procedure of data which is measured with a CCD (Charge-Coupled Device) sensor unit. The invention is preferably used in photometrics for measuring ra...
08/31/2004
6770460Fusion protein and its use in an immunoassay for the simultaneous detection of autoantibodies related to insulin-dependent diabetes mellitus
The invention relates to a fusion protein having epitopes of at least two of the autoantigens glutamic acid decarboxylase (GAD65), islet cell antigen (IA2) and preproinsulin (PPINS) wherenin said epitopes are connected with a linker peptide. The fusion protein must ...
08/03/2004
6377346Sample imaging device
An imaging device for biochemical or medical samples, the pulse mode light source of which incorporates flash lamps and a rotating mirror in an inclined position, the said mirror reflecting the light emitted by each flash lamp in turn along the same optic...
04/23/2002
6244119Multichannel pipette system and pipette tips therefor
The present invention relates generally to a multichannel pipetting system that can be used with a plurality of well plates used for medical, biological or biochemical research involving liquid materials. The system includes a multichannel pipettor and no...
06/12/2001
6127529Metal-chelating 2,6-disubstituted pyridine compounds and their use
Bifuncitonal chelating pyridine compound and its use for conferring chelating properties on organic compounds. The pyridine compound has the structure ##STR1## where (i) n is an integer 1 or 2, (ii) R1, R2 and R3 repr...
10/03/2000
6112603Method and a device for handling sample plates
A method for handling a microplate, in which liquid (22) is dosed into a sample well (21) and the liquid is removed and, if necessary, the sample wells are further washed and/or rinsed. According to the invention, the liquid to be dosed is dosed into the ...
09/05/2000
6080839Labeling reactants and their use
The invention relates to a novel labeling reactant, suitable for labeling of a biospecific binding reactant using solid-phase synthesis. The invention further concerns new labeling methods. The novel labeling reactant has the formula (I) ##STR1## ...
06/27/2000
6051191Microplates
There is disclosed a microplate affording an array of discrete, separate sample wells in which each sample well consists of a well of a first polymer composition, the well having side walls and a base, and being located in a matrix of a second polymer com...
04/18/2000
6042785Multilabel measurement instrument
A compact optical instrument for performing various laboratory measurements utilizing different technologies of spectroscopy, i.e., photoluminescence, absorption and chemical luminescence, from liquid and solid samples. The measuring head of the instrumen...
03/28/2000
5998146Homogeneous luminescence assay method based on energy transfer
The invention is a luminescence energy transfer based bioaffinity assay comprising a first group labeled with an energy donating compound (donor) and a second group labeled with an energy accepting compound (acceptor), wherein the donor is a luminescent l...
12/07/1999
5859215Biospecific binding reactants labelled with luminescent lanthanide chelates and their use
This invention relates to a detectable molecule comprising a biospecific binding reactant attached to a luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of the formula ##STR1## wherein --A-- is a bivalent aromatic str...
01/12/1999
5780857Apparatus for imaging biochemical samples on substrates
A multi-purpose optical scanner that is provided for performing different type of high sensitivity imaging of planar biochemical samples. These types of samples include stimulable phosphor image plates, fluorescently labelled samples like electrophoretic ...
07/14/1998
5637509Modulated homogeneous fluorescence biospecific affinity assay employing fluorescing lanthanide chelates as covalent labels
Method for a homogeneous biospecific affinity assay for determining the content of a substance (analyte) in a biological sample. The assay is carried out in an aqueous reaction medium by means of time-resolved fluorescence spectroscopy and with a biospeci...
06/10/1997
5571897Luminescent lanthanide chelates
Lanthanide chelates which contain three heterocyclic rings covalently coupled to each other (either one 2,6-pyridylene and two five-membered unsaturated heterocyclic ring moieties or two 2,6-pyridylene and one five-membered unsaturated heterocyclic ring m...
11/05/1996
5548111Photomultiplier having gain stabilization means
A gain stabilization system for photomultiplier tubes using a pulsed light source, preferably a light emitting diode (LED), the signal of which is detected at the cathode and at the anode. The gain of photomultiplier tube is stabilized by keeping the rati...
08/20/1996
5460057Method and apparatus for handling samples and sample collection system
Method for handling blood samples (32) wherein a blood sample is absorbed into a filter paper (30) and a sample piece (36) is taken from the filter paper from the opposite side of the absorption side. The sample piece is placed in a sample well of an unco...
10/24/1995
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