Assignee: Wakamoto Pharmaceutical Co., Ltd.

Location: Tokyo, JP
No. of patents: 29

Number	Title	Issue Date
8153601	Azithromycin-containing aqueous pharmaceutical composition and a method for the preparation of the same The invention provides an azithromycin-containing aqueous pharmaceutical composition, which comprises at least one member selected from the group consisting of azithromycin, and pharmaceutically acceptable salts thereof, and at least one member selected from the gro...	04/10/2012
7612115	Aqueous pharmaceutical compositions The present invention has an object to provide an antibacterial aqueous pharmaceutical composition and an aqueous pharmaceutical composition which have a sufficiently low gelation temperature even when new quinolone antibacterial agents such as ofloxacin as the acti...	11/03/2009
7225949	Liquid drug container A liquid drug container comprises a container body 1; a nozzle member 2 liquid-tightly mounted on the container body 1; and a nozzle cap 6 fitted on the nozzle member 2. A nozzle hole 231 of the nozzle member 2 is cov...	06/05/2007
7150986	Lactic acid bacteria-containing probiotics products The present invention provides a probiotics product comprising, as an effective component, lactic acid bacteria belonging to Lactobacillus salivarius possessing high adhesiveness to mucous membrane, a high proliferation ability and a high resistance to acids,...	12/19/2006
7105512	Ophthalmic aqueous pharmaceutical preparation The present invention provides an ophthalmic aqueous pharmaceutical preparation, which is excellent in anti-inflammatory effect, which is less stimulative and which has high safety and excellent storage stability. The ophthalmic aqueous pharmaceutical preparation co...	09/12/2006
6849419	Monoclonal antibody hybridoma immunoassay method and diagnosis kit The object of the present invention is to provide a diagnostic method by which Helicobacter pylori infection can be diagnosed at low cost without causing pain on subjects and without requiring particular equipment and which is free of cross reactivity and exc...	02/01/2005
6777197	Method and test kit for measuring immunoglobulins reactive with amylase as indication of crohn's disease A method for diagnosing Crohn's disease by detecting the presence of immunoglobulins, reactive with an amylase, in a specimen by an immunologic or enzymologic method using the amylase, and a test kit for this method. ...	08/17/2004
6495603	Anti-inflammatory eye drop The present invention relates to an anti-inflammatory eye drop comprising a drug selectively inhibiting COX-2, selected from the group consisting of etodolac, N-(2-(cyclohexyloxy)-4-nitrophenyl) methane-sulfonamide and meloxicam, which only slightly damag...	12/17/2002
6432439	O/W emulsion composition An O/W emulsion composition comprising fluorometholone or clobetasone butyrate, a phospholipid, an oil, a nonionic water-soluble cellulose derivative, and water. The O/W composition has advantages that fluorometholone or clobetasone butyrate contained the...	08/13/2002
6225306	Biphenyl derivatives and drug composition A biphenyl derivative represented by the following general formula (1) and a pharmaceutically acceptable salt thereof: ##STR1## [In the formula (1), A represents a single bond, --CH2 --, --CO--, --CS-- or --SO2 --; B represents a sin...	05/01/2001
6132751	O/W emulsion composition for eye drops An O/W emulsion composition for eye drops comprises a drug selected from the group consisting of fluorometholone, clobetasone butyrate and clobetasol propionate; a phospholipid; liquid paraffine; and water. The O/W emulsion composition is excellent in sol...	10/17/2000
5929115	Anti-inflammatory eye drop An anti-inflammatory eye drop comprises (a) 0.05 to 0.7 weight/volume % of diclofenac sodium; (b) 1 to 10 weight/volume % of γ-cyclodextrin; (c) 1 to 20 weight/volume % of polyvinyl pyrrolidone; and (d) 0.002 to 0.01 weight/volume % of benzethonium chloride or 0.002 to...	07/27/1999
5756552	Lyophilized pharmaceutical preparations capable of providing aqueous drug composition having property of reversible thermosetting gelation Herein disclosed is a lyophilized pharmaceutical preparation obtained by lyophilizing an aqueous composition having property of reversible thermosetting gelation and comprising an effective amount of a drug, 0.2 to 2.1 (W/V)% of methylcellulose (the conte...	05/26/1998
5693337	Stable lipid emulsion A lipid emulsion which comprises (A) an oil component, (B) an emulsifying agent containing yolk lecithin and/or soybean lecithin, and (C) water, wherein the lipid emulsion further comprises citric acid or a pharmaceutically acceptable salt thereof and at ...	12/02/1997
5648455	Antibiotic WAP-8294A, method for preparing the same and antibacterial composition Antibiotics WAP-8294A, A1, A2, A4, AX, AX-8, AX-9 and AX-13 or pharmeceutically acceptable salts thereof produced by a strain belonging to the genus Lysobacter; a method for producing the foregoing antibiotic WAP-8294A com...	07/15/1997
5624962	Aqueous drug composition having property of reversible thermosetting gelation An aqueous drug composition having property of reversible thermosetting gelation for ophthalmic, dermatological and body cavitical use which comprises effective amount of drugs used for pharmaceutical therapy or diagnosis, methylcellulose, citric acid and...	04/29/1997
5602161	Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component The tetrazolylphenyl pivalate of the the following general formula or a pharmaceutically acceptable salt thereof: ##STR1## wherein R1 and R2 each represents a hydrogen atom, a lower alkyl group or other substituents; an elastase...	02/11/1997
5569464	Stable aqueous dispersions containing liposomes An aqueous dispersion containing liposomes comprising yolk lecithin and/or soybean lecithin as lipids for forming liposomes wherein the dispersion contains a hydroxy acid and an amino acid, which hardly shows coloration, shows little leak of drugs encapsu...	10/29/1996
5356916	1,2,4-oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity A 1,2,4-oxadiazole derivative is represented by the following general formula (I): ##STR1## wherein R1 represents a lower alkyl or cycloalkyl group, a lower alkyl group substituted with a halogen atom, a lower alkylamino group or a ph...	10/18/1994
5262433	Tetrazoleacetic acid derivatives and method of aldose reductase inhibition therewith A tetrazoleacetic acid derivative represented by the following general formula I: ##STR1## wherein in the formula I, R represents a hydrogen atom or a lower alkyl group; A is an alkylene group having 2 to 5 carbon atoms; Ar is selected from the ...	11/16/1993
5252592	Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity A tetrazoleacetic acid derivative represented by the following general formula (I): ##STR1## [in Formula (I), R1 represents a hydrogen atom or a lower alkyl group; R2, R3 and R4 are the same or different fr...	10/12/1993
5246835	Method of diagnosing renal diseases A method of diagnosing renal diseases by detecting fragments of albumin in human urine. The detection of the fragments is carried out by, for example, immunological methods or liquid chromatography techniques....	09/21/1993
5068239	Tetrazoleacetic acid derivatives and use for aldose reductase inhibitory activity A tetrazoleacetic acid derivative represented by the following general formula (I): ##STR1## [in Formula (I), R1 represents a hydrogen atom or an alkyl group; R2 represents a hydrogen atom, an alkyl group, an aralkyl group, a ...	11/26/1991
5055481	Tetrazole derivatives and aldose reductase inhibition therewith The present invention relates to an aldose reductase inhibitor having the following formula: ##STR1## R1 is a hydrogen atom or --A--COOR5 (A is an alkylene group having 1 to 4 carbon atoms and R5 is a hydrogen atom or...	10/08/1991
4861718	Gene coding for thermostable beta-galactosidase, bacillus subtilis having the gene, enzyme coded by the gene and a process for the production thereof A novel gene coding for thermostable ଲ-galactosidase, novel recombinant DNA in which a DNA fragment containing the above gene is inserted, novel Bacillus subtilis in which the above recombinant DNA is introduced, and novel thermostable ଲ-galac...	08/29/1989
4795754	3-(1H-tetrazol-5-y1)oxanilic acid and salts thereof and pharmaceutical compositions containing them A new compound, 3-(1H-tetrazol-5-yl)oxanilic acid and pharmaceutically acceptable salts thereof are herein disclosed, which can be prepared by reacting 3-(1H-tetrazol-5-yl)aniline with a compound represented by the general formula: A--CO--CO--B (wherein A...	01/03/1989
4778816	Anti-asthmatic composition and process for preparing the same 5-(3-n-Butyloxalylaminophenyl) tetrazole having an excellent SRS-A release-inhibiting effect is used as an effective component for an anti-asthmatic agent, and a pharmaceutical preparation obtained by mixing the tetrazole with a specific dispersant such a...	10/18/1988
4587254	1,3,4-thiadiazole derivatives, process for the production thereof and use thereof as antiulcer agent New 1,3,4-thiadiazole derivatives of the general formula (I): ##STR1## wherein R1 represents a group of the formula: ##STR2## and R2 represents an amino, lower alkylamino, cyclohexylamino, benzoylamino, mercapto or lower al...	05/06/1986
4537967	1-Oxo-1,2,3,4-tetrahydro-3-isoquinoline carboxylic acid derivatives The following new isocarbostyryl derivatives represented by the general formula [I]: ##STR1## wherein R1 is a hydrogen atom or a lower alkyl group, are provided, said derivatives having excellent angiotensin converting enzyme inhibitory ...	08/27/1985

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Assignee: Wakamoto Pharmaceutical Co., Ltd.