Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 7371857 | Synthesis for hydroxyalkylated heterocyclic bases A hydroxyalkylated heterocyclic base is prepared by reacting a heterocyclic base with an alkylene carbonate in dimethylacetamide as a solvent, wherein the hydroxyalkylated heterocyclic base is isolated from the solvent using isopropanol or tert-butylmethylether.... | 05/13/2008 |
| 7247621 | Antiviral phosphonate compounds and methods therefor Pharmaceutical compositions comprise a nucleotide analog with a phosphonate group at a concentration effective to act as a substrate and/or inhibitor of a viral polymerase, and especially of the HCV RNA dependent RNA polymerase. ... | 07/24/2007 |
| 7189724 | Quinoxaline derivatives having antiviral activity The invention provides substituted quinoxalines having the general formulas where R1, R2, R3, and R4 are, inter alia, alkyl, aryl, or heteroaryl groups; Z is NH or O; a... | 03/13/2007 |
| 7081449 | Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides A purine nucleoside analog includes a pyrido[2,3-d]pyrimidine or a pyrimido[4,5-d]pyrimidine and further has a sugar moiety that is optionally modified at the C2′, C3′, C4′ and/or C5′ position. Particularly contemplated compounds also include prodrug forms o... | 07/25/2006 |
| 6994959 | G-rich oligo aptamers and methods of modulating an immune response Aptamer oligonucleotides specifically bind to the DNA binding site of proteins such as Sp1 and Sp1-related proteins which regulate the genes which encode costimulatory molecules such as CD28 and cytokines such as IL-2 and GMCSF. The oligonucleotides compete with the... | 02/07/2006 |
| 6989451 | Heterocyclic compounds and uses thereof Substituted isothiazole compounds and compositions are provided, wherein particularly preferred compositions and methods are directed towards inhibition of various protein kinases (especially MEK and/or ERK). Consequently, particularly preferred methods include trea... | 01/24/2006 |
| 6930093 | Use of ribofuranose derivatives against inflammatory bowel diseases A method for the prophylaxis or treatment of an inflammatory bowel disease is provided, comprising administering to a patient having or at risk of developing an inflammatory bowel disease a therapeutically or preventatively effective amount of one or more ribofurano... | 08/16/2005 |
