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| Number | Title | Issue Date |
| 8183236 | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics Pharmacophore models to be used in drug design and discovery are provided. An in silico protocol and in vitro assays are presented. Compounds and their pharmaceutically acceptable salts with HIV-1 integrase inhibitory and anti-HIV activity and use thereof in the tre... | 05/22/2012 |
| 8181540 | Measurement of sliding friction-induced vibrations for biomimetic tactile sensing Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. The deformable properties of t... | 05/22/2012 |
| 8164484 | Detection and classification of running vehicles based on acoustic signatures A method and apparatus for identifying running vehicles in an area to be monitored using acoustic signature recognition. The apparatus includes an input sensor for capturing an acoustic waveform produced by a vehicle source, and a processing system. The waveform is ... | 04/24/2012 |
| 8163502 | Method for predicting the risk of disease based on lectin binding Provided are methods, test devices, and diagnostic kits for predicting, assessing, and diagnosing the risk of a disease using salivary analysis. The methods comprise providing a whole (unfractionated) saliva sample from a subject; contacting an aliquot of the saliva... | 04/24/2012 |
| 8148509 | Transgene delivering retrovirus targeting collagen exposed at site of tissue injury A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds to an extracellular matrix component. Such vector particles are usefu... | 04/03/2012 |
| 8148124 | Regulation of gene expression by protein methylation The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine... | 04/03/2012 |
| 8139846 | Verification of integrated circuits against malicious circuit insertions and modifications using non-destructive X-ray microscopy A method and system for verifying the integrity of integrated circuits (ICs) by detecting the presence of unauthorized circuit insertions or modifications using non-destructive x-ray microscopy is disclosed. A reference image based on a trusted IC or a trusted desig... | 03/20/2012 |
| 8138380 | Electrolysis of carbon dioxide in aqueous media to carbon monoxide and hydrogen for production of methanol An environmentally beneficial method of producing methanol from varied sources of carbon dioxide including flue gases of fossil fuel burning power plants, industrial exhaust gases or the atmosphere itself. Converting carbon dioxide by an electrochemical reduction of... | 03/20/2012 |
| 8134555 | Acquisition of surface normal maps from spherical gradient illumination An apparatus for generating a surface normal map of an object may include a plurality of light sources having intensities that are controllable so as to generate one or more gradient illumination patterns. The light sources are configured and arranged to illuminate ... | 03/13/2012 |
| 8133926 | Conversion of carbon dioxide to dimethyl ether using bi-reforming of methane or natural gas The invention provides for a method of forming dimethyl ether by bimolecular dehydration of methanol produced from a mixture of hydrogen and carbon dioxide obtained by reforming of methane, water and carbon dioxide in a ratio of about 3:2:1. Subsequent use of water ... | 03/13/2012 |
| 8131011 | Human detection and tracking system A human tracking system for tracking a plurality of humans in motion, in a video of the humans in motion, includes a human detection subsystem, and a combined tracker. The human detection subsystem is configured to generate a detection output by detecting the plural... | 03/06/2012 |
| 8126261 | 3D face reconstruction from 2D images A 3D face reconstruction technique using 2D images, such as photographs of a face, is described. Prior face knowledge or a generic face is used to extract sparse 3D information from the images and to identify image pairs. Bundle adjustment is carried out to determin... | 02/28/2012 |
| 8124066 | Methods of using interleukin-2 mutants with reduced toxicity Interleukin-2 (IL-2) mutants having reduced toxicity, which include full-length IL-2, truncated forms of IL-2 and forms of IL-2 that are linked to another molecule are disclosed herein. Particular substitutions within IL-2, particularly within the permeability enhan... | 02/28/2012 |
| 8123706 | Frequency-based methods, system and apparatus for cavity reconstruction via area-distance profiles A method, system and apparatus for Resonance-Based Acoustic Reflectometry that uses a hybrid approach. A method of manufacture, system and apparatus for a modified circle system that allows for the connection of extra devices like exemplary embodiments of the presen... | 02/28/2012 |
| 8120207 | Nanosecond pulse generator with a protector circuit This invention relates to a pulse generator circuit for delivering a short high current pulse to a load. This pulse generator comprises a junction recovery diode, a switch, a first resonant circuit and a second resonant circuit. The diode may be configured to store ... | 02/21/2012 |
| 8115343 | Nanosecond pulse generator This invention relates to a pulse generator circuit for delivering a short high current pulse to a load. This pulse generator comprises a junction recovery diode, a switch, a first resonant circuit and a second resonant circuit. The diode may be configured to store ... | 02/14/2012 |
| 8115023 | Benzo lipoxin analogues Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of various diseases, including, inflammation, autoimmune disease and abnormal... | 02/14/2012 |
| 8114289 | Method and apparatus for microfiltration to perform cell separation A microfiltration apparatus and method for separating cells, such as circulating tumor cells, from a sample using a microfiltration device having a top porous membrane and a bottom porous membrane. The porous membranes are formed from parylene and assembled using mi... | 02/14/2012 |
| 8111402 | Optical sensing based on overlapping optical modes in optical resonator sensors and interferometric sensors Techniques and devices based on transverse magnetic (TM) and transverse electric (TE) modes in an optical resonator or interferometer to provide sensitive optical detection with insensitivity to a change in temperature. A shift in a difference between a first resona... | 02/07/2012 |
| 8111174 | Acoustic signature recognition of running vehicles using spectro-temporal dynamic neural network A method and apparatus for identifying running vehicles in an area to be monitored using acoustic signature recognition. The apparatus includes an input sensor for capturing an acoustic waveform produced by a vehicle source, and a processing system. The waveform is ... | 02/07/2012 |
| 8110542 | Methods of expressing proteins with disulfide bridges This invention relates to methods of expressing eukaryotic proteins in prokaryotic hosts, particularly eukaryotic proteins that require formation of disulfide bridges for biological activity. Various approaches are used including fusion to thioredoxin, cytoplasmic e... | 02/07/2012 |
| 8100184 | Collection and lift modules for use in a wellbore A system for a gas-producing wellbore comprises a collection module disposed about a gas-production conduit in the wellbore, the collection module comprising a collection chamber disposed about the gas-production conduit. The system further comprises one or more lif... | 01/24/2012 |
| 8099380 | Blind evaluation of nearest neighbor queries wherein locations of users are transformed into a transformed space using a plurality of keys Systems and techniques are described for blind evaluation of nearest neighbor queries. Locations of multiple users in an original space are received. The locations in the original space are encoded into encoded locations in a transformed space. A relative proximity ... | 01/17/2012 |
| 8094118 | Dynamic backlight scaling for power minimization in a backlit TFT-LCD An embodiment of the present invention is directed to a method for determining a pixel transformation function that maximizes backlight dimming while maintaining a pre-specified distortion level. The method includes determining a minimum dynamic range of pixel value... | 01/10/2012 |
| 8093417 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 01/10/2012 |
| 8090730 | Methods for fast progressive evaluation of polynomial range-sum queries on real-time datacubes Provided are methods, computer programs and systems that optimize database queries using a wavelet transform of the query. Also provided are methods and systems for optimal disk placement for wavelet data. ... | 01/03/2012 |
| 8086975 | Power aware asynchronous circuits Techniques are described for converting netlists for synchronous circuits such as combinational modules, flip flops (or latches), and clock gating modules, to netlist of asynchronous modules. Processes including algorithms are described that bundle multiple modules ... | 12/27/2011 |
| 8084438 | Compositions and methods of sphingosine kinase inhibitors in radiation therapy of various cancers The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention further relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and potentiate... | 12/27/2011 |
| 8082870 | Multiplex-thruster systems for delivering thrusting flow Designs and techniques for fluid thrusters and vehicles that are powered by propelling fluids with fluid thrusters. Multiplex-thruster (MT) systems are disclosed that include a single thruster and a flow multiplexer with multiple channels to deliver thrusting flow i... | 12/27/2011 |
| 8080652 | Gene silencing using mRNA-cDNA hybrids The present invention provides novel compositions and methods for suppressing the expression of a targeted gene using mRNA-cDNA duplexes. The invention further provides novel methods and compositions for generating amplified mRNA-cDNA hybrids, whose quantity is high... | 12/20/2011 |
| 8080593 | Reversible thermoresponsive adhesives for implants The present invention relates to thermoresponsive adhesives. The invention further relates to methods for the reversible attachment of retinal implants, other implants, and drug delivery devices. ... | 12/20/2011 |
| 8077036 | Systems and methods for security breach detection A system for detecting and classifying a security breach may include at least one sensor configured to detect seismic vibration from a source, and to generate an output signal that represents the detected seismic vibration. The system may further include a controlle... | 12/13/2011 |
| 8076070 | Genome-wide chromosome conformation capture The invention relates to the use of GCC (Genome Conformation Capture) technology in determining the three dimensional arrangement of an entire genome. ... | 12/13/2011 |
| 8073196 | Detection and tracking of moving objects from a moving platform in presence of strong parallax Among other things, methods, systems and computer program products are described for detecting and tracking a moving object in a scene. One or more residual pixels are identified from video data. At least two geometric constraints are applied to the identified one o... | 12/06/2011 |
| 8052966 | Methods and compositions for treating metastatic cancer Methods and compositions for producing targeted delivery vectors are provided. Such vectors are useful for treating neoplastic disorders. Also provided are protocols for administering targeted delivery vectors in a clinical setting such that a therapeutic effect is ... | 11/08/2011 |
| 8047251 | Reduction of powder waste in selective inhibition of sintering Disclosed are methods and systems for selective inhibition of sintering in 3D fabrication. The disclosure provides methods and systems that use selective heating arrangements to selectively sinter areas during fabrication thereby reducing waste improving efficiency.... | 11/01/2011 |
| 8041417 | Method and system for dynamical systems modeling of electrocardiogram data Electrocardiogram data is received in association with a subject, the electrocardiogram data comprising a series of RR intervals and a series of QT intervals. A first value which indicates an amount by which uncertainty associated with the QT intervals is reduced gi... | 10/18/2011 |
| 8032356 | Spoken translation system using meta information strings Spoken translation system which detects both speech from the information and also detects meta information streams from the information. A first aspect produces an enriched training corpus of information for use in the machine translation. A second aspect uses two d... | 10/04/2011 |
| 8032355 | Socially cognizant translation by detecting and transforming elements of politeness and respect A socially-cognizant translation system that takes social state between speaker and listener into account when making the translation. The translation may be more formal or less formal based on the social relationship between speaker and listener. Profanities in the... | 10/04/2011 |
| 8029710 | Gantry robotics system and related material transport for contour crafting Apparatus and methods are disclosed that are useful for robotic gantry systems that are lightweight while at the same time offering rigidity or stiffness for implementation in Contour Crafting construction and material delivery techniques. The present disclosure is ... | 10/04/2011 |
