Assignee: University of Pittsburgh of the Commonwealth System of Higher Education

Location: Pittsburgh, PA
No. of patents: 124

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Number	Title	Issue Date
8162925	Robot for minimally invasive interventions Rather than trying to immobilize a living, moving organ to place the organ in the fixed frame of reference of a table-mounted robotic device, the present disclosure teaches mounting a robot in the moving frame of reference of the organ. That task can be accomplished...	04/24/2012
8085406	Ultrafast microscopy of surface electromagnetic fields System(s) and method(s) to probe electromagnetic fields at the surface of a solid-state material are provided. The technique combines ultrafast (e.g., less than 10 fs) optical excitation and electron microscopy to generate electronic excitations and image the ensuin...	12/27/2011
8007504	Device and method of use for functional isolation of animal or human tissues A method and apparatus for functionally occluding the lumen of the left atrial appendage (LAA) is provided. Access to the LAA is through an epicardial approach. The devices function to capture the LAA through various non-invasive means. After capturing the LAA with ...	08/30/2011
7897569	Use of HMGB fragments as anti-inflammatory agents Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise a vertebrate HMGB A box, and an antibody preparation t...	03/01/2011
7829536	Method of treating lymphedema comprising administering VEGF-D The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects. ...	11/09/2010
7732180	Porcine Forssman synthetase protein, cDNA, genomic organization, and regulatory region The present invention provides porcine Forssman synthetase (FSM synthase) (Globoside α-N-acetylgalactosaminyltransferase) protein, cDNA, and genomic DNA sequence. Furthermore, the present invention includes porcine animals, tissue and organs as well as cells and ce...	06/08/2010
7711174	Methods and systems for imaging cells The invention generally provides methods and systems for determining characteristics of cellular structures. The methods include non-invasive, non-perturbing, automatable, and quantitative methods and may be applied to the examination of cells such as stem cells, em...	05/04/2010
7704503	Use of IL-17F in diagnosis and therapy of airway inflammation The invention is related to findings that IL-17F-mediated inflammation of airway passages may be mediated via signaling through IL-17R on the basolateral surface of human respiratory epithelial cells. Thus, the present invention provides isolated and purified IL-17F...	04/27/2010
7691416	Methods of treating vascular disease The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient. ...	04/06/2010
7662793	Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from a Pol III promoter A nucleic acid is provided comprising an expression cassette which includes transcription control sequences of a member of a class of Pol III-transcribed genes in which no transcribed portion of the Pol III gene is required for transcription of the gene. In the expr...	02/16/2010
7629315	Compositions for blocking the inhibitory effect of human CRP on human leptin Leptin controls the production of C-Reactive Protein (CRP), which, in turn, interacts with leptin to diminish its ability to signal satiety and reduce food intake. The interactions between leptin and CRP can be exploited to screen for agents capable of disrupting th...	12/08/2009
7598042	Early prostate cancer antigens (EPCA), polynucleotide sequences encoding them, and their use A novel prostate cancer marker is described that is found in cancerous and normal prostate cells of individuals that have prostate cancer but is not found in the prostate of individuals without prostate cancer. The marker also is present in normal tissue adjacent to...	10/06/2009
7597695	Posterior oblique lumbar arthrodesis Instruments and methods for spinal stabilization are disclosed. In preferred embodiments, the invention provides greater stabilization of vertebral bodies through methods including combinations of external fixation systems and intervertebral implants to provide grea...	10/06/2009
7572596	Modulation of the neuroendoctrine system as a therapy for motor neuron disease The invention provides a method for treating amyotrophic lateral sclerosis (ALS) in a subject. The method comprises administering to the nervous system of the subject a composition comprising a thyroxine protein or a therapeutic fragment or pharmacologic mimic there...	08/11/2009
7444179	Devices, systems and methods for characterization of ventricular fibrillation and for treatment of ventricular fibrillation A method of determining a state of ventricular fibrillation, includes: measuring the rhythm of the heart during ventricular fibrillation for a period of time; creating a lagged phase space reconstruction of the measured rhythm; determining a first value related to t...	10/28/2008
7440780	Recharging method and apparatus The present invention provides apparatus and an associated method for remotely energizing power storage devices. Energization may preferably be effected through the use of RF energy from a base station, ambient energy or ultra-wide band energy. The remote station pr...	10/21/2008
7403803	Recharging method and associated apparatus The present invention provides apparatus and an associated method for remotely energizing power storage devices. Energization may preferably be effected through the use of RF energy within frequencies of the wireless fidelity standards. The remote station preferably...	07/22/2008
7390631	Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma Methods for diagnosing and monitoring systemic lupus erythematosus (SLE) or scleroderma by determining, in a blood sample from the individual being diagnosed or monitored, complement component C4d deposited on surfaces of red blood cells in the sample, and optionall...	06/24/2008
7383064	Recharging method and associated apparatus The present invention provides apparatus and an associated method for remotely energizing power storage devices. Energization may preferably be effected through the use of RF energy within frequencies of the wireless fidelity standards. The remote station preferably...	06/03/2008
7373133	Recharging method and apparatus The present invention provides apparatus and an associated method for remotely energizing power storage devices. Energization may preferably be effected through the use of RF energy from a base station, ambient energy or ultra-wide band energy. The remote station pr...	05/13/2008
7364757	Methods of treating vascular disease The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient. ...	04/29/2008
7364908	Separation of fluorous compounds A method of separating at least a first non-fluorous compound from a mixture of compounds including at least the first non-fluorous compound and a second fluorous compound includes: charging the of compounds to a non-fluorous solid (stationary) phase and eluting wit...	04/29/2008
7349600	Active in-fiber optic components powered by in-fiber light An optical fiber system that includes an in-fiber optic component powered by in-fiber light includes an optical fiber having a core, wherein the optical fiber propagates a sensing/signal light and a power light, with the sensing/signal light being propagated in the ...	03/25/2008
7332479	Extracellular NAD and cADPR as potent anti-inflammatory agents A method of prophylaxis or treatment of inflammatory conditions, including, but not limited to, intestinal epithelial inflammation due to intestine-specific conditions (e.g., Crohn's disease or ulcerative colitis) or systemic causes of inflammation (e.g., endotoxemi...	02/19/2008
7304034	Use of HMGB fragments as anti-inflammatory agents Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise a vertebrate HMGB A box, and an antibody preparation t...	12/04/2007
7297337	EphA2 T-cell epitopes and uses therefor EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as...	11/20/2007
7283053	RFID radio frequency identification or property monitoring method and associated apparatus A method of identifying an article of interest includes providing one of a plurality of RF antennas each having a non-linear element which may be a rectifying diode and being resident at a different frequency on the article of interest. One RF antenna is interrogate...	10/16/2007
7258444	Method and apparatus for screening for retinopathy A method of screening for retinal disease including directing a first light at a first portion of the retina, directing a second light at a second portion of the retina, measuring a first pupillary response of the eye as a result of the first light and a second pupi...	08/21/2007
7239778	Active in-fiber optic components powered by in-fiber light An optical fiber system that includes an in-fiber optic component powered by in-fiber light includes an optical fiber having a core, wherein the optical fiber propagates a sensing/signal light and a power light, with the sensing/signal light being propagated in the ...	07/03/2007
7228183	Method of data communication with implanted device and associated apparatus Apparatus and method of communicating data employing current pulses transmitted by an implanted device through living biological tissue to an external device. The method also contemplates transmission of current pulses from the external device through living biologi...	06/05/2007
7105494	Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies The present invention relates to a method for treating bone pathologies comprising delivering a viral or non-viral delivery vehicle comprising genetic information (e.g. a transgene) encoding a therapeutic osteoinductive factor to target cells in vivo enabling the ce...	09/12/2006
7078029	Herpes simplex virus strains The present invention provides an HSV having a genome with a mutation of a TAATGARAT sequence such that, in the presence of a ICP4 gene product, a native immediate early gene is expressed from the genome with delayed kinetics, the genome having a further inactivatin...	07/18/2006
7057514	Antenna on a wireless untethered device such as a chip or printed circuit board for harvesting energy from space A wireless untethered device which may be an integrated circuit chip or printed circuit board having at least one integrated antenna and circuitry operatively associated with the antenna for receipt of energy harvested from space by the antenna. The antenna has an e...	06/06/2006
7037492	Gene transfer for studying and treating a connective tissue of a mammalian host Methods for introducing at least one gene encoding a product into at least one target cell of a mammalian host for use in treating the mammalian host are disclosed. These methods include employing recombinant techniques to produce a vector molecule that contains the...	05/02/2006
6847844	Method of data communication with implanted device and associated apparatus Apparatus and method of communicating data employing current pulses transmitted by an implanted device through living biological tissue to an external device. The method also contemplates transmission of current pulses from the external device through living biologi...	01/25/2005
6776764	Use of aortic pulse pressure and flow in bedside hemodynamic management A treatment algorithm for managing hemodynamically unstable patients is provided. Specifically, measurements of arterial pressure and stroke volume can be used to calculate pulse pressure variation, stroke volume variation, mean arterial pressure, elastance and card...	08/17/2004
6737270	Long-term three dimensional tissue culture system A method is provided for long term culture of proliferating hepatocytes that retain hepatic function to produce a hepatic cell culture. Hepatocytes and nonparenchymal cells are co-cultured ex vivo on a matrix coated with a molecule that promotes cell adhesion, proli...	05/18/2004
6734880	User interface for a medical informatics systems A user interface for a medical informatics system, which permits a physician to work with digitized medical images in a manner that the physician is accustomed to working with traditional analog film, is disclosed. The user interface includes a through a patient bro...	05/11/2004
6712990	Magnetorheological fluids and related method of preparation Magnetorheological (MR) fluids, dispersions of magnetically soft particles in fluids (gases, liquids, or semi-solids such as greases), are disclosed. The present invention uses the initial steps of a sol-gel process to assist in preparation of MR fluids that have si...	03/30/2004
6615074	Apparatus for energizing a remote station and related method Apparatus for remote interaction with an object of interest includes a remote station for obtaining information from the object of interest, a base station for transmitting energy in space to and communicating with the remote station and the remote statio...	09/02/2003

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Assignee: University of Pittsburgh of the Commonwealth System of Higher Education