Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education

Location: Pittsburgh, PA
No. of patents: 36

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Number	Title	Issue Date
8184885	System and method for visualizing a structure of interest A system. The system includes a computing device configured for communication with an imaging system and with a display device. The computing device includes a contour modeling module. The contour modeling module is configured for superimposing reference anchors on ...	05/22/2012
8158110	Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease The present invention relates to methods and compositions for prevention of graft rejection in lung transplant recipients and for treatment of subjects with pulmonary disorders. Specifically, the methods and compositions of the invention provide a means for inhibiti...	04/17/2012
8126654	Identification and monitoring of systemic lupus erythematosus A method for identifying or monitoring SLE in an individual is provided. The method includes quantitating complement component C4d on the surfaces of platelets and comparing the amounts of C4d to reference levels of C4d on platelets of individuals without SLE and/or...	02/28/2012
8091790	Security for blister packs Various RFID based blister pack embodiments are provided for improving the ability to detect and prevent tampering and counterfeiting of blister packs and/or facilitating the chain of custody tracking of blister packs during manufacture. Some embodiments employ an R...	01/10/2012
8080382	Monitoring immunologic, hematologic and inflammatory diseases This invention relates to the diagnosis and/or monitoring of patients with inflammatory diseases or conditions, e.g., immunologic, hematologic, vascular, or infectious diseases or conditions, by determining levels of complement pathway components on erythrocytes. Me...	12/20/2011
8043411	Devices, systems and methods for reducing the concentration of a chemical entity in fluids A device for removal of at least a portion of carbon dioxide from an aqueous fluid includes at least one membrane through which carbon dioxide can pass to be removed from the fluid and immobilized carbonic anhydrase on or in the vicinity of a first surface of the me...	10/25/2011
7992999	Automated assessment of optic nerve head with spectral domain optical coherence tomography A fully automated optic nerve head assessment system, based on spectral domain optical coherence tomography, provides essential disc parameters for clinical analysis, early detection, and monitoring of progression. ...	08/09/2011
7981038	Sensor guided catheter navigation system A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D sur...	07/19/2011
7933861	Process data warehouse Systems and/or methods are presented that can efficiently analyze and summarize large collections of data. A summarization component can employ mapping rules to map received data into specified states and observations of interest, which can be utilized to facilitate...	04/26/2011
7907769	Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell colonies, individual cells, and/or cellular structures. ...	03/15/2011
7887792	Muscle-derived cells (MDCs) for treating muscle- or bone-related injury or dysfunction The present invention provides muscle-derived cells, preferably myoblasts and muscle-derived stem cells, genetically engineered to contain and express one or more heterologous genes or functional segments of such genes, for delivery of the encoded gene products at o...	02/15/2011
7876225	Methods and apparatus for switching a transponder to an active state, and asset management systems employing same A transponder that may be used as an RFID tag includes a passive circuit to eliminate the need for an “always on” active RF receiving element to anticipate a wake-up signal for the balance of the transponder electronics. This solution allows the entire active tr...	01/25/2011
7872027	Low molecular weight Myc-max inhibitors Compounds and compositions for interfering with the association of Myc and Max are described herein. These compounds and compositions are useful in methods inhibiting growth or proliferation of a cell. Methods of inhibiting growth or proliferation of a cell are prov...	01/18/2011
7858657	Wortmannin analogs and methods of using same in combination with chemotherapeutic agents Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic a...	12/28/2010
7829097	Use of HMGB1 for protection against ischemia reperfusion injury Methods and compositions are disclosed for protecting an organ or tissue from inflammation and organ injury following ischemia, reperfusion, and trauma through the administration of an HMGB1 protein within a time period sufficient to protect the organ or tiss...	11/09/2010
7825807	Transponder networks and transponder systems employing a touch probe reader device Transponder networks and transponder systems are provided which help to overcome the issues presented to transponders systems by FCC power limitations. One embodiment provides a transponder network that includes a plurality of RFID straps in order to increase the am...	11/02/2010
7791557	Multiple antenna energy harvesting Energy harvesting circuits and associated methods are provided that employ multiple antennas to optimize the amount of energy that is harvested while at the same time making efficient use of tag space. In some embodiments, matching networks are chosen in a manner th...	09/07/2010
7781164	Method for diagnosing renal diseases or predispositions The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a mutation in the UMOD supports a diagnosis of a disease or a predispos...	08/24/2010
7750632	Method for producing a magnetic resonance image of an object having a short Trelaxation time A method for producing a magnetic resonance image using an ultra-short echo time. The method includes applying a pulse sequence to an object, detecting a spirally encoded and phase encoded magnetic resonance signal associated with the object, and reconstructing the ...	07/06/2010
7747274	Method and system for securely communicating information using multiple RF carriers Amplitude modulation of multiple carriers provides a pulse width modulated train resulting in a novel and effective communication mechanism to overcome difficulties in certain RF applications, particularly in the area of Radio Frequency Identification (RFID). A nove...	06/29/2010
7734077	Method of assessing localized shape and temperature of the human body A method of objectively quantifying assessments of joints having arthritis for purposes of assessment, diagnosis and treatment. The objective measurements utilize known imaging modalities including 3D scanning, thermal imaging, visible and near-infrared imaging and ...	06/08/2010
7704507	Anticancer vaccine and diagnostic methods and reagents The invention provides a method for vaccinating a patient against a malignancy comprising introducing a protein or peptide comprising of all or an immunogenic fragment of a cyclin protein into the patient. The invention further provides a method of identifying tumor...	04/27/2010
7700794	Fluorous tagging compounds and methods of increasing the fluorous nature of compounds A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having the formula: wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m ...	04/20/2010
7678057	Device and system that identifies cardiovascular insufficiency In an embodiment, the present invention provides a device that identifies cardiovascular dysfunction of a subject. The claimed device comprises a controller, a transducer, and a processor. The controller initiates collection of a plurality of data related to a physi...	03/16/2010
7672732	Portable apparatus that delivers power and information to implantable devices An apparatus for powering an implant includes first energy interface elements, a removeably attachable holding device and a first energy source, such as a battery. An energy conversion circuit converts first energy into second energy which is transmitted within the ...	03/02/2010
7655640	Camptothecin analogs and methods of preparation thereof A method of inhibiting topoisomerase I mediated DNA cleavage including administering a pharmaceutically effective amount of a compound having the following formula or a pharmaceutically acceptable salt thereof: wherein R	02/02/2010
7612162	Peptide analogs capable of enhancing stimulation of a glioma-specific CTL response The invention provides a peptide derived from the interleukin-13 receptor α2, which serves as a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope. The invention can be used as a vaccine for glioma and can be formulated into compositions for medical or veterina...	11/03/2009
7588905	Identification and monitoring of systemic lupus erythematosus A method for identifying or monitoring SLE in an individual is provided. The method includes quantitating complement component C4d on the surfaces of platelets and comparing the amounts of C4d to reference levels of C4d on platelets of individuals without SLE and/or...	09/15/2009
7550568	Monoclonal antibodies to human high molecular weight-melanoma associated antigen The present invention provides monoclonal antibodies that react against high molecular weight melanoma-associated antigen. These antibodies may be used for diagnostic and/or therapeutic purposes. ...	06/23/2009
7547472	Polymer and method for using the polymer for noncovalently functionalizing nanotubes A new, non-wrapping approach to functionalizing nanotubes, such as carbon nanotubes, in organic and inorganic solvents is provided. In accordance with certain embodiments, carbon nanotube surfaces are functionalized in a non-wrapping fashion by functional conjugated...	06/16/2009
7538220	Intermediates in the preparation of homocamptothecin analogs A compound having the formula in racemic form, enantiomerically enriched form or enantiomerically pure form; wherein X is a radical precursor; R5 is a C1-10 alkyl group, an alkenyl group, an alkynyl gr...	05/26/2009
7531167	Herpes simplex virus vector The invention provides a herpes simplex virus vector comprising deletions in ICP4, ICP27, and UL55. ...	05/12/2009
7524653	Small interfering RNA libraries and methods of synthesis and use In one aspect, the invention provides a random or semirandom siRNA (encoding) library. Another aspect of the invention pertains to methods for construction of random or semirandom siRNA (encoding) libraries. Another aspect of the invention is vector systems for use ...	04/28/2009
7494566	Composition for increasing cellulosic product strength and method of increasing cellulosic product strength A composition includes water; at least one hydrophilic polymer containing at least two groups which are independently the same or different a primary amine group or a secondary amine group and at least one saccharide containing a reducible function as described abov...	02/24/2009
7480876	Method and software tool for designing an integrated circuit A method of designing an integrated circuit for an application having standards having a plurality of primitives, each of the primitives having a corresponding response. The method includes generating a macros description of each of the primitives and the response c...	01/20/2009
7469390	Method and software tool for automatic generation of software for integrated circuit processors A method of generating software code for a processor of an IC based on a simple input description of the IC's standards. The method includes generating a macros description of each of the primitives from the standards and the response corresponding to each of the pr...	12/23/2008

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Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education