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Assignee: University of Miami


Location: Miami, FL
No. of patents: 80

1    
NumberTitleIssue Date
8156168Method and system for data security
A method, system and apparatus that advantageously provide a security protocol for data security. The apparatus includes a random number generator for generating random numbers and a share calculator in communication with the random number generator, the share calcu...
04/10/2012
8153436Assays for disease-associated crystals in biological samples
Methods of assaying for disease-associated crystal species in biological samples are described. Such methods involve contacting a patient sample with an excess of a detectable crystal-tagging compound reactive with a plurality of crystal species under conditions tha...
04/10/2012
8147825Topical co-enzyme Q10 formulations and methods of use
Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing an...
04/03/2012
8105632Cell-derived microparticles as hemostatic agents for control of hemorrhage and treatment of bleeding disorders
Compositions comprising membrane-derived and synthetic microparticles that induce platelet aggregation and are useful for treating bleeding disorders, particularly those involving platelet dysfunction. Microparticles include endothelial derived microparticles (EMP),...
01/31/2012
8099147Intraoperative monitoring of temperature-induced tissue changes with a high-resolution digital X-ray system during thermotherapy
A method of thermally inducing and monitoring changes to localized regions of tissue illuminating a volume of tissue with a first beam of X-rays, detecting the portions of the first beam of X-rays that passed through the volume of tissue, generating a first X-ray im...
01/17/2012
8088591Biomarkers for detection and diagnosis of head and neck squamous cell carcinoma
Novel, sensitive and specific markers and methods for diagnostics and monitoring of head and neck squamous cell carcinoma (HNSCC) are provided. Kits and methods for the use of hyaluronic acid, hyaluronidase and CD44 to diagnose HNSCC are described. ...
01/03/2012
7924429Enhanced optical coherence tomography for anatomical mapping
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma...
04/12/2011
7910359Hybrid device for cell therapies
A device for receiving implanted biological material includes a porous outer wall defining an inner space, a fluid manifold assembly for selectively infusing at least one of immunosuppressive and growth factor media to said space, and a pump structure operatively co...
03/22/2011
D616805Co-flow jet aircraft
06/01/2010
7718177Antibodies directed to fragments of connective tissue growth factor (CTGF) polypeptide and methods and uses thereof
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis and myofibroblast differentiation. The present invention is further di...
05/18/2010
7713686Organ preservation container and method
An organ preservation container includes a gas impermeable housing for containing an organ. At least two liquids having different densities and forming a liquid-liquid interface are also contained in the housing. A closure for hermetically sealing the housing is pro...
05/11/2010
7659990Enhanced optical coherence tomography for anatomical mapping
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma...
02/09/2010
7655391Method for shipping items in an aircraft
A container for shipping items in an aircraft includes a shipping compartment and an expandable chamber for receiving gas from the shipping compartment. At least one conduit connects the expandable chamber to the shipping department so as to permit the flow of gas t...
02/02/2010
7505142Enhanced optical coherence tomography for anatomical mapping
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma...
03/17/2009
7496226Multi-camera inspection of underwater structures
A method, system and apparatus for viewing and imaging an underwater structure from a submersible platform, navigating along the structure and constructing a map of the structure in the forms of a photo-mosaic and a 3-D structural map. The system can include a subme...
02/24/2009
7413874Nucleic acid encoding fluorescent proteins from aquatic species
Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from
08/19/2008
7384743BRCA1/BCRA2 screening panel
A method for analyzing a biological sample is performed by analyzing a biological sample for the presence of one or more mutations or polymorphisms in the BCRA1 and/or BCRA2 genes. ...
06/10/2008
7301644Enhanced optical coherence tomography for anatomical mapping
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma...
11/27/2007
7291711Fluorescent proteins from aquatic species
Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from
11/06/2007
7285282Mucin peptide with immunoenhancing properties
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and ...
10/23/2007
7262162Ubiquitin and ubiquitin related molecules for treatment and prevention of harmful activation of the immune system
Compositions and methods for suppressing the immune system of a mammal using ubiquitin and derivatives and analogs thereof. ...
08/28/2007
7219164Multimedia re-editor
A method and system for processing a re-editable multimedia document. A method for processing a re-editable multimedia document can include the steps of loading an electronic text file; associating at least one external multimedia element with a selected portion of ...
05/15/2007
7188994Orbital shaker for cell extraction
A orbital shaker for cell extraction includes a digestion chamber and structure for translating the digestion chamber. Structure is also provided for rotating the digestion chamber. A method of performing cell extraction is also disclosed. ...
03/13/2007
7186549Container for shipping items in aircraft
A container for shipping items in an aircraft includes a shipping compartment and an expandable chamber for receiving gas from the shipping compartment. At least one conduit connects the expandable chamber to the shipping department so as to permit the flow of gas t...
03/06/2007
7115390Connective tissue growth factor fragments and methods and uses thereof
The present invention is directed to CTGF fragments comprising at least exon 4 or exon 5 of CTGF and having mitogenic activity. The present invention is further directed to methods using said CTGF fragments to identify compositions which modulate the mitogenic activ...
10/03/2006
6897022Susceptability and resistance genes for bipolar affective disorder
Chromosomal regions comprising loci associated with susceptibility and resistance to bipolar affective disorder have been identified. Methods and compositions are provided for determining the contribution of these chromosomal regions to bipolar affective disorder in...
05/24/2005
6882702Intensity modulated radiotherapy inverse planning algorithm
A method in a computer for optimizing a dosage of intensity modulated radiotherapy (IMRT) comprises the steps of: dividing a three dimensional (3D) volume into a grid of dose voxels, wherein each dose voxel receives a dose of radiation from at least one pencil beam ...
04/19/2005
6872812Hepp, a novel gene with a role in hematopoietic and neural development
The invention is directed to an isolated gene and protein product, designated Hepp, which has a role in mammalian hematopoiesis and neural function, and is further directed to a genetically modified non-human mammal that is homozygous or heterozygous for a disruptio...
03/29/2005
6684097Intraoperative monitoring of temperature-induced tissue changes with a high-resolution digital x-ray system during thermotherapy
A method of thermally inducing and monitoring changes to localized regions of tissue illuminating a volume of tissue with a first beam of X-rays, detecting portions of the first beam of X-rays, generating a first X-ray image signal from the detected X-ray...
01/27/2004
6671529System and method for closed loop controlled inspired oxygen concentration
A system and method for delivering fractionally inspired oxygen (FiO2) to a patient in response to receiving an arterial hemoglobin oxygen saturation signal (SpO2) are disclosed. The SpO2 is measured, for example, by using...
12/30/2003
6608176Taste receptor for umami (monosodium glutamate) taste
A metabotropic glutamate taste receptor having a molecular weight of approximately 68 kDa, encoded by a cDNA sequence having the mRNA sequence of SEQ ID NO:1 is disclosed, which functions as a umami taste receptor. Also disclosed are cells expressing the ...
08/19/2003
6582465Integrated rigid fixation orbital expander
An integrated rigid fixation orbital expander has a coupling tunnel, an injection port, and a substantially spherically shaped expansion chamber. The coupling tunnel is configured with opposing side walls, a top wall and a bottom wall. The top wall of the...
06/24/2003
6536272Water monitoring, data collection, and transmission module
A water sampling apparatus is disclosed having a water inlet and a water collecting scoop. A pump, in fluid communication with the water inlet, draws a water sample from a body of water through the water inlet. A plurality of testing units, in fluid commu...
03/25/2003
6492129Fragments of connective tissue growth factor that induce extracellular matrix synthesis, collagen synthesis and/or myofibroblast differentiation
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis and myofibroblast differentiation. The present invention is...
12/10/2002
6464983Methods and uses of connective tissue growth factor for differentiation of mesenchymal stem cells
The present invention relates to novel methods and compositions related to the administration of connective tissue growth factor, alone or in combination with other growth factors, compositions or compounds, to induce the differentiation of mesenchymal st...
10/15/2002
6429204Method of inhibiting cancer growth
The invention is a method of inhibiting a sarcoma, such as Kaposi's sarcoma, in a mammal. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3.)...
08/06/2002
6406695Treatment of hepatitis C by administration of anti-IL-2 receptor monoclonal antibody
A novel method using anti-interleukin 2 receptor monoclonal antibodies for treating patients having severe viral hepatitis C is described. The inventive method may be used to treat recurrent hepatitis C following liver transplantation, thereby reducing co...
06/18/2002
6358279Minicapsulorhexis valve
A mini capsulorhexis valve device is composed of a curved, flexible discoid flap-valve member shaped to align with an ocular lens capsular bag inner surface, and a curved, flexible retainer member shaped to align with an ocular lens capsular bag outer sur...
03/19/2002
6236459Thin film measuring device and method
An interferometric thin film measuring device has a source of illumination light, a detector disposed in a return path of light reflected from a specimen of illumination light, a plurality of wavelength filters that filter light into image channels, a wei...
05/22/2001
6207408High quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
A process and apparatus for rapid, continuous flow histological processing of tissues is disclosed. The steps of fixation, dehydration, clearing and impregnation are performed in less than one hour; this allows a pathologist to evaluate samples shortly af...
03/27/2001
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