"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 8156168 | Method and system for data security A method, system and apparatus that advantageously provide a security protocol for data security. The apparatus includes a random number generator for generating random numbers and a share calculator in communication with the random number generator, the share calcu... | 04/10/2012 |
| 8153436 | Assays for disease-associated crystals in biological samples Methods of assaying for disease-associated crystal species in biological samples are described. Such methods involve contacting a patient sample with an excess of a detectable crystal-tagging compound reactive with a plurality of crystal species under conditions tha... | 04/10/2012 |
| 8147825 | Topical co-enzyme Q10 formulations and methods of use Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing an... | 04/03/2012 |
| 8105632 | Cell-derived microparticles as hemostatic agents for control of hemorrhage and treatment of bleeding disorders Compositions comprising membrane-derived and synthetic microparticles that induce platelet aggregation and are useful for treating bleeding disorders, particularly those involving platelet dysfunction. Microparticles include endothelial derived microparticles (EMP),... | 01/31/2012 |
| 8099147 | Intraoperative monitoring of temperature-induced tissue changes with a high-resolution digital X-ray system during thermotherapy A method of thermally inducing and monitoring changes to localized regions of tissue illuminating a volume of tissue with a first beam of X-rays, detecting the portions of the first beam of X-rays that passed through the volume of tissue, generating a first X-ray im... | 01/17/2012 |
| 8088591 | Biomarkers for detection and diagnosis of head and neck squamous cell carcinoma Novel, sensitive and specific markers and methods for diagnostics and monitoring of head and neck squamous cell carcinoma (HNSCC) are provided. Kits and methods for the use of hyaluronic acid, hyaluronidase and CD44 to diagnose HNSCC are described. ... | 01/03/2012 |
| 7924429 | Enhanced optical coherence tomography for anatomical mapping A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma... | 04/12/2011 |
| 7910359 | Hybrid device for cell therapies A device for receiving implanted biological material includes a porous outer wall defining an inner space, a fluid manifold assembly for selectively infusing at least one of immunosuppressive and growth factor media to said space, and a pump structure operatively co... | 03/22/2011 |
| D616805 | Co-flow jet aircraft | 06/01/2010 |
| 7718177 | Antibodies directed to fragments of connective tissue growth factor (CTGF) polypeptide and methods and uses thereof The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis and myofibroblast differentiation. The present invention is further di... | 05/18/2010 |
| 7713686 | Organ preservation container and method An organ preservation container includes a gas impermeable housing for containing an organ. At least two liquids having different densities and forming a liquid-liquid interface are also contained in the housing. A closure for hermetically sealing the housing is pro... | 05/11/2010 |
| 7659990 | Enhanced optical coherence tomography for anatomical mapping A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma... | 02/09/2010 |
| 7655391 | Method for shipping items in an aircraft A container for shipping items in an aircraft includes a shipping compartment and an expandable chamber for receiving gas from the shipping compartment. At least one conduit connects the expandable chamber to the shipping department so as to permit the flow of gas t... | 02/02/2010 |
| 7505142 | Enhanced optical coherence tomography for anatomical mapping A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma... | 03/17/2009 |
| 7496226 | Multi-camera inspection of underwater structures A method, system and apparatus for viewing and imaging an underwater structure from a submersible platform, navigating along the structure and constructing a map of the structure in the forms of a photo-mosaic and a 3-D structural map. The system can include a subme... | 02/24/2009 |
| 7413874 | Nucleic acid encoding fluorescent proteins from aquatic species Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from | 08/19/2008 |
| 7384743 | BRCA1/BCRA2 screening panel A method for analyzing a biological sample is performed by analyzing a biological sample for the presence of one or more mutations or polymorphisms in the BCRA1 and/or BCRA2 genes. ... | 06/10/2008 |
| 7301644 | Enhanced optical coherence tomography for anatomical mapping A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral doma... | 11/27/2007 |
| 7291711 | Fluorescent proteins from aquatic species Provided are four new fluorescent proteins. The proteins were derived from two wild-type fluorescent proteins: a red fluorescent protein (RFP) that was isolated from Actinodiscus or Discosoma sp. 1 and a green fluorescent protein (GFP) isolated from | 11/06/2007 |
| 7285282 | Mucin peptide with immunoenhancing properties An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and ... | 10/23/2007 |
| 7262162 | Ubiquitin and ubiquitin related molecules for treatment and prevention of harmful activation of the immune system Compositions and methods for suppressing the immune system of a mammal using ubiquitin and derivatives and analogs thereof. ... | 08/28/2007 |
| 7219164 | Multimedia re-editor A method and system for processing a re-editable multimedia document. A method for processing a re-editable multimedia document can include the steps of loading an electronic text file; associating at least one external multimedia element with a selected portion of ... | 05/15/2007 |
| 7188994 | Orbital shaker for cell extraction A orbital shaker for cell extraction includes a digestion chamber and structure for translating the digestion chamber. Structure is also provided for rotating the digestion chamber. A method of performing cell extraction is also disclosed. ... | 03/13/2007 |
| 7186549 | Container for shipping items in aircraft A container for shipping items in an aircraft includes a shipping compartment and an expandable chamber for receiving gas from the shipping compartment. At least one conduit connects the expandable chamber to the shipping department so as to permit the flow of gas t... | 03/06/2007 |
| 7115390 | Connective tissue growth factor fragments and methods and uses thereof The present invention is directed to CTGF fragments comprising at least exon 4 or exon 5 of CTGF and having mitogenic activity. The present invention is further directed to methods using said CTGF fragments to identify compositions which modulate the mitogenic activ... | 10/03/2006 |
| 6897022 | Susceptability and resistance genes for bipolar affective disorder Chromosomal regions comprising loci associated with susceptibility and resistance to bipolar affective disorder have been identified. Methods and compositions are provided for determining the contribution of these chromosomal regions to bipolar affective disorder in... | 05/24/2005 |
| 6882702 | Intensity modulated radiotherapy inverse planning algorithm A method in a computer for optimizing a dosage of intensity modulated radiotherapy (IMRT) comprises the steps of: dividing a three dimensional (3D) volume into a grid of dose voxels, wherein each dose voxel receives a dose of radiation from at least one pencil beam ... | 04/19/2005 |
| 6872812 | Hepp, a novel gene with a role in hematopoietic and neural development The invention is directed to an isolated gene and protein product, designated Hepp, which has a role in mammalian hematopoiesis and neural function, and is further directed to a genetically modified non-human mammal that is homozygous or heterozygous for a disruptio... | 03/29/2005 |
| 6684097 | Intraoperative monitoring of temperature-induced tissue changes with a high-resolution digital x-ray system during thermotherapy A method of thermally inducing and monitoring changes to localized regions of tissue illuminating a volume of tissue with a first beam of X-rays, detecting portions of the first beam of X-rays, generating a first X-ray image signal from the detected X-ray... | 01/27/2004 |
| 6671529 | System and method for closed loop controlled inspired oxygen concentration A system and method for delivering fractionally inspired oxygen (FiO2) to a patient in response to receiving an arterial hemoglobin oxygen saturation signal (SpO2) are disclosed. The SpO2 is measured, for example, by using... | 12/30/2003 |
| 6608176 | Taste receptor for umami (monosodium glutamate) taste A metabotropic glutamate taste receptor having a molecular weight of approximately 68 kDa, encoded by a cDNA sequence having the mRNA sequence of SEQ ID NO:1 is disclosed, which functions as a umami taste receptor. Also disclosed are cells expressing the ... | 08/19/2003 |
| 6582465 | Integrated rigid fixation orbital expander An integrated rigid fixation orbital expander has a coupling tunnel, an injection port, and a substantially spherically shaped expansion chamber. The coupling tunnel is configured with opposing side walls, a top wall and a bottom wall. The top wall of the... | 06/24/2003 |
| 6536272 | Water monitoring, data collection, and transmission module A water sampling apparatus is disclosed having a water inlet and a water collecting scoop. A pump, in fluid communication with the water inlet, draws a water sample from a body of water through the water inlet. A plurality of testing units, in fluid commu... | 03/25/2003 |
| 6492129 | Fragments of connective tissue growth factor that induce extracellular matrix synthesis, collagen synthesis and/or myofibroblast differentiation The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis and myofibroblast differentiation. The present invention is... | 12/10/2002 |
| 6464983 | Methods and uses of connective tissue growth factor for differentiation of mesenchymal stem cells The present invention relates to novel methods and compositions related to the administration of connective tissue growth factor, alone or in combination with other growth factors, compositions or compounds, to induce the differentiation of mesenchymal st... | 10/15/2002 |
| 6429204 | Method of inhibiting cancer growth The invention is a method of inhibiting a sarcoma, such as Kaposi's sarcoma, in a mammal. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3.)... | 08/06/2002 |
| 6406695 | Treatment of hepatitis C by administration of anti-IL-2 receptor monoclonal antibody A novel method using anti-interleukin 2 receptor monoclonal antibodies for treating patients having severe viral hepatitis C is described. The inventive method may be used to treat recurrent hepatitis C following liver transplantation, thereby reducing co... | 06/18/2002 |
| 6358279 | Minicapsulorhexis valve A mini capsulorhexis valve device is composed of a curved, flexible discoid flap-valve member shaped to align with an ocular lens capsular bag inner surface, and a curved, flexible retainer member shaped to align with an ocular lens capsular bag outer sur... | 03/19/2002 |
| 6236459 | Thin film measuring device and method An interferometric thin film measuring device has a source of illumination light, a detector disposed in a return path of light reflected from a specimen of illumination light, a plurality of wavelength filters that filter light into image channels, a wei... | 05/22/2001 |
| 6207408 | High quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method A process and apparatus for rapid, continuous flow histological processing of tissues is disclosed. The steps of fixation, dehydration, clearing and impregnation are performed in less than one hour; this allows a pathologist to evaluate samples shortly af... | 03/27/2001 |