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| Number | Title | Issue Date |
| 7850958 | Recombinant double stranded RNA nucleocapsid and use of the same A recombinant double stranded RNA (dsRNA) nucleocapsid useful for the expression of dsRNA expression cassettes encoding passenger genes, such as, but not restricted to, vaccine antigens, bioactive proteins, immunoregulatory proteins, antisense RNAs, and catalytic RN... | 12/14/2010 |
| 7732215 | Cyanide sensing compounds and uses thereof The present invention relates to a cyanide detection method using fluorescence and cyanide sensitive boronic acid containing fluorophores, wherein a change in a measured fluorescent property correlates to the concentration of the cyanide compound in a biological or ... | 06/08/2010 |
| 7728106 | HIV-1 glycopeptides and derivatives; preparation and applications thereof A method of making a synthetic glycopeptide, by addition of a synthetic oligosaccharide oxazoline to a GlcNAc-containing peptide precursor in the presence of an enzyme selected from among Endo-A and Endo-M. In a specific implementation, the method is utilized to syn... | 06/01/2010 |
| 7718804 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes, such as aqueous chloride and iodide, and a method of using the compounds.... | 05/18/2010 |
| 7632634 | Method and assay for early diagnosis of prostate cancer A method and assay are described for determining prostate cancer and the general stage of progression of such cancer by quantifying levels of expression of different galectin isoforms and/or different levels of promoter methylation of such galectin isoforms. ... | 12/15/2009 |
| 7604804 | Enhancing anti-HIV efficiency through multivalent inhibitors targeting oligomeric gp120 The present invention relates to multivalent HIV inhibitors that bind to multiple sites on a trimeric gp120 complex thereby blocking the CD4 binding site on the trimeric gp120 complex and inhibiting the attachment and entry of HIV through gp120-CD4 interactions.... | 10/20/2009 |
| 7569219 | Recombinant double-stranded RNA phage, and use of the same A recombinant double stranded RNA (dsRNA) phage expresses dsRNA-encoded genes in eukaryote cells. Recombinant dsRNA phage are useful for the expression of dsRNA expression cassettes encoding passenger genes, such as, but not restricted to, vaccine antigens, bioactiv... | 08/04/2009 |
| 7556806 | Carbohydrate-based synthetic vaccines for HIV The present invention relates to a constructed oligosaccharide cluster, optionally bonded to an immunogenic protein, that can be administered to a subject to induce an immune response for increasing production of 2G12 and/or used in assays as reactive sites for dete... | 07/07/2009 |
| 7524821 | Scaffolded maleimide clusters for multivalent peptide assembly Disclosed are scaffolded maleimide clusters, methods of making said clusters and use of said clusters as templates for multivalent peptide assembly. Multiple maleimide functionalities were introduced onto a scaffold molecule by the reaction of a core-centered polyam... | 04/28/2009 |
| 7491399 | In Ovo vaccine against infectious bursal disease The present invention relates to a non pathogenic vaccine comprising a recombinant Infectious Bursal Disease virus that includes a recombinant Segment A, designated as rD78GLSNSĪ, that includes sequences from D78 and GLS strains and wherein the NS protein is not ex... | 02/17/2009 |
| 7462480 | Stimulation of microbial dechlorination of polychorinated biphenyls with halogenated ethenes Disclosed is a method for the anaerobic microbial dechlorination of polychlorinated biphenyls (PCBs). Polyhalogenated ethenes are used to stimulate the growth and dechlorinating activity of PCB dechlorinating bacteria in a contaminated soil or sediment. This method ... | 12/09/2008 |
| 7462284 | Dissimilatory sulfate reduction as a process to promote denitrification in marine recirculating aquaculture systems The present invention relates to a novel approach for nitrate removal from a marine recirculating system (10) wherein high concentrations of sulfate found in seawater is used in combination with sludge (20) collected from fish growing tanks (12)... | 12/09/2008 |
| 7407790 | Recombinant double-stranded RNA phages and uses thereof The present invention provides recombinant double stranded RNA phages (rdsRP) that express dsRNA-encoded genes in eukaryote cells. Recombinant dsRNA phages are useful for the expression of dsRNA expression cassettes encoding passenger genes, such as, but not restric... | 08/05/2008 |
| 7399473 | Virus coat protein/receptor chimeras and method of use The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can inter-act with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties charac... | 07/15/2008 |
| 7384641 | Immuno-modulating effects of chemokines in DNA vaccination The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine. ... | 06/10/2008 |
| 7375404 | Fabrication and integration of polymeric bioMEMS A micro-electro-mechanical system (MEMS) device is provided, along with means for its fabrication and operation for microfluidic and/or biomicrofluidic applications. The MEMS device includes a substrate, optional electrodes on the substrate, a patterned structure on... | 05/20/2008 |
| 7314741 | Anaerobic ammonium oxidation for water treatment in recirculating aquaculture Disclosed herein are planctomycetes sp. which convert ammonia to nitrogen under anaerobic conditions, filtration and aquaculture systems comprising said bacteria, filtration media comprising said bacteria, and methods of filtration using said bacteria. ... | 01/01/2008 |
| 7311920 | Virus coat protein/receptor chimeras and methods of use The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can interact with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties charact... | 12/25/2007 |
| 7247432 | Enhanced protein thermostability and temperature resistance Small heat shock proteins, e.g., Pyrococcus fuiosus (Pfu-sHSP and/or Pfu-tsHSP), confer thermotolerance on cellular cultures and on proteins in cellular extracts during prolonged incubation at elevated temperature, demonstrating the ability to protect cellula... | 07/24/2007 |
| 7244432 | Infectious bursal disease virus (IBDV) variant from Georgia A VP2 protein isolated from a variant Georgia strain of Infectious Bursal Disease Virus (IBDV) and method of generating such VP2 protein and variant strain for use to reduce or prevent infection in poultry by IBDV. ... | 07/17/2007 |
| 7194978 | Inducing sterility in fish by disrupting the development of the GnRH system The present invention provides for a method for inducing sterility in fish by administering at least one compound that disrupts the establishment of the gonadotropin-releasing hormone system during early development thereby inhibiting sexual maturity in the treated ... | 03/27/2007 |
| 7138373 | Polysaccharide-based polymers and methods of making the same Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine residues. Specific polysaccharides include, but are not limited to, chitosan. ... | 11/21/2006 |
| 7125718 | Method for introducing and expressing genes in animal cells, and bacterial blebs for use in same A method for introducing and expressing genes in animal cells, in which the animal cells are transfected with bacterial blebs containing a eukaryotic expression cassette encoding the gene. Bacterial blebs comprising a eukaryotic expression cassette, wherein the bact... | 10/24/2006 |
| RE39270 | Process for continuous optimized protein production in insect larvae The present invention provides for a recombinant insect larvae and a process of manufacturing proteins utilizing insect larvae that allows for the selection of individual larvae for harvest at the point of their optimal expression of a protein of interest. This inve... | 09/05/2006 |
| 7082893 | Aquaculture nitrogen waste removal The present invention relates to a two-stage biofilter reactor system for removing nitrogenous compounds from a recirculating aquaculture system. The system includes a aerobic nitrification unit and a downstream anaerobic denitrification unit, wherein both units hav... | 08/01/2006 |
| 7067145 | Use of arachidonic acid for enhanced culturing of fish larvae and broodstock A method of enhancing a culturing characteristic of fish larvae, including administering to said larvae in a nutritional diet essential fatty acids including DHA and AA in a ratio effective to enhance the culturing characteristic of such fish larvae relative to a co... | 06/27/2006 |
| 7033767 | Genes regulating programmed cell death The present invention to amino acid sequences of proteins that are associated with apoptosis and the use of these proteins in the diagnosis, prevention and treatment of disorders associated with abnormal cell proliferation and apoptosis. The invention relates as wel... | 04/25/2006 |
| 6936256 | Sub-unit vaccine for infectious pancreatic necrosis virus The present invention relates to sub-unit vaccines comprising structural polypeptides of Infectious Pancreatic Necrosis Virus (IPNV) comprising structural proteins VP2 and VP3 folded as an empty IPNV viral capsid that approximates the size and structural conformatio... | 08/30/2005 |
| 6919319 | Immuno-modulating effects of chemokines in DNA vaccination The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine. ... | 07/19/2005 |
| 6908612 | Virus coat protein/receptor chimeras and methods of use The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can inter-act with each other to form a complex that is capable of binding a co-receptor. Such chimeric molecules therefore exhibit functional properties charac... | 06/21/2005 |
| 6841345 | Treatment and prevention of immunodeficiency virus infection by administration of non-pyrogenic derivatives of lipid A The present inventors have found that certain preparations containing LPS and/or lipid A variants, derivatives, and/or analogs demonstrate non-pyrogenic properties and exhibit anti-viral activities. In particular, non-pyrogenic preparations of LPS, lipid A, LPS anta... | 01/11/2005 |
| 6805882 | Therapeutic fractions of sources of HCG The present invention relates to fractions of sources and or preparations of human chorionic gonadotropin, such as fractions of human early pregnancy urine, which fractions have anti-HIV activity. The present invention further relates to pharmaceutical compositions ... | 10/19/2004 |
| 6803479 | Reagents and method for spatio-temporal control of gene expression by illumination A caged non-steroidal ecdysome memetic (NSE) compound and a method for producing free NSE by subjecting the charged NSE to UV irradiation. ... | 10/12/2004 |
| 6759195 | Method of differential display of prokaryotic messenger RNA by RTPCR The present invention provides a method of differential display of prokaryotic messages RNA by RTPCR, the method comprising the steps of: adding a first primer mixture to a first nucleic acid sample including a first mixture of mRNA to form a first primer/first nucl... | 07/06/2004 |
| 6759241 | Adjuvant comprising a lipopolysaccharide antagonist LPS preparations, isolated from gram negative bacterial strains that contain at least one mutation in at least one of the htrB and msbB genes, and methods and therapeutics related thereto. The LPS preparations display both LPS antagonist and adjuvant activities.... | 07/06/2004 |
| 6699656 | Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin The present invention relates to ଲ-hCG, particularly ଲ-hCG proteins having a sequence of amino acids 41-54, 45-54, 47-53, 45-57 and 45-58 and analogs and derivatives thereof. The invention further relates to methods of treatment and prevention... | 03/02/2004 |
| 6699834 | Method for treating cancer The present invention relates to peptides of one or more portions of the human chorionic gonadotropin ଲ-chain as well as methods for treatment of cancer, using human chorionic gonadotropin, employing the ଲ-chain of human chorionic gonadotropin... | 03/02/2004 |
| 6660904 | HIV and CD4 transgenic animals and uses therefor The invention provides transgenic animals comprising a lentiviral transgene, such as an HIV transgene. Also within the scope of the invention are cells and eggs from the transgenic animal. Further included are methods for identifying therapeutic compounds... | 12/09/2003 |
| 6620985 | PAD4 nucleic acid compositions from Arabidopsis and methods therefor PAD4 compositions from Arabidopsis, including genomic and cDNA nucleic acid sequences, and methods for using said compositions in plants are provided. PAD4 from Arabidopsis is demonstrated to be regulatory and is required upstream from salicylic acid in t... | 09/16/2003 |
| 6620416 | Method for treating HIV The present invention relates to peptides of one or more portions of the human chorionic gonadotropin ଲ-chain as well as methods for treatment and prevention of diseases, including HIV infection, using human chorionic gonadotropin, employing the ... | 09/16/2003 |