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Vladimir Zworykin, television pioneer ; Talking about an invention in which he played a critical role.
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| Number | Title | Issue Date |
| 8178678 | -quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of c... | 05/15/2012 |
| 8138309 | Modified rubisco large subunit n-methyltransferase useful for targeting molecules to the active-site vicinity of ribulose-1,5-bisphosphate The present invention generally relates to a modified Rubisco large subunit εN-Methyltransferase (Rubisco LSMT, or RLSMT). The present invention also relates to a modified RLSMT-carbonic anhydrase (RLSMT-CA). This modified RLSMT-CA improves the efficienc... | 03/20/2012 |
| 8124851 | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involv... | 02/28/2012 |
| 8115059 | Gene expression modulation system for use in plants and method for modulating gene expression in plants An EcR-based gene expression modulation system for use in plants includes an EcR gene expression cassette, a modified RXR gene expression cassette, and a gene-of-interest expression cassette, which can be expressed in a host plant cell. ... | 02/14/2012 |
| 8110184 | Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells and/or differentiated cells of the blood lineage. The present methods en... | 02/07/2012 |
| 8101779 | Enantioselective synthesis of (+) and (–)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene Methods for the enantioselective synthesis of (+) and (−) lofexidine or 2-[1-(2,6)-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene involve converting (+) or (−) 1-methyl-1-[2,6-dichlorophenoxy]ethanamide to an (+) or (−) imino-ether intermediate by electrophi... | 01/24/2012 |
| 8101354 | Method for screening for a tobiano coat color genotype A method for screening for a Tobiano genotype includes obtaining a nucleic acid from an equine animal, and analyzing the nucleic acid for the presence of an inversion in a chromosome ECA3q which is indicative of the genotype for Tobiano. The method includes detectin... | 01/24/2012 |
| 8067432 | Liposomal, ring-opened camptothecins with prolonged, site-specific delivery of active drug to solid tumors A method for preparing a stable dispersion of a camptothecin, camptothecin prodrug, or analog thereof for administration to a patient in need thereof includes preparing a solution of the camptothecin, wherein the solution has a pH which places substantially an entir... | 11/29/2011 |
| 8066883 | Removing aluminum from solution using chelating compounds and immobilized tethered chelators Methods are described for removing aluminum from a solution using novel di- and tripodal compounds as chelators. ... | 11/29/2011 |
| 8053633 | Fungal desaturases and related methods The presently-disclosed subject matter provides isolated nucleic acid and amino acid sequences encoding mushroom desaturase polypeptides that are active with both palmitic and stearic acid, as well as vectors and transgenic plant cells comprising nucleic acids of th... | 11/08/2011 |
| 8042405 | Method and apparatus for characterizing microscale formability of thin sheet materials A method of predicting sheet formability at a microscale level includes the steps of providing a grid pattern on a test sheet, bulging the test sheet to a hemispherical shape until a crack is initiated on the surface of the test sheet, detecting the initiation of th... | 10/25/2011 |
| 8030358 | Methods and pharmaceutical compositions for decorporation of radioactive compounds A composition for removing a radioactive element or compound such as systemic transuranic compounds, from mammals comprises a pharmaceutical carrier and a decorporation agent comprising ester and amide derivatives of DTPA. A method of treating a mammal to remove sys... | 10/04/2011 |
| 8017835 | Transformed plants accumulating terpenes The present invention relates to transformed plants with an altered terpene content, preferably over-accumulating a mono- or sesqui-terpene. By transformation of plants with genes encoding terpene synthases (TS), and prenyl transferases (PRT), plants accumulating at... | 09/13/2011 |
| 8012735 | Infectious cDNA clone of the modified live virus vaccine strain of virus An isolated polynucleotide molecule includes a DNA sequence encoding an infectious RNA molecule encoding a modified live viral strain of an Equine arteritis virus, wherein the DNA sequence is SEQ ID NO:1 or a degenerate variant thereof. Also provided are transformed... | 09/06/2011 |
| 8008092 | CCR3 inhibition for ocular angiogenesis and macular degeneration Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of inhibitors of the CCR3 receptor or its ligands eotaxin (CCL11), eotaxin-2 (CCL24) or eotaxin-3 (CCL26) inhibits ocular angiogenesis... | 08/30/2011 |
| 7985568 | triterpene synthase proteins and nucleic acid molecules, and methods for their use This application relates to the functional identification and characterization of a nucleic acid molecule encoding a triterpene synthase, in particular botryococcene synthase. Also described are host cells comprising the nucleic acid molecules of this invention, pro... | 07/26/2011 |
| 7982041 | Camptothecin analogs and methods of preparation thereof A compound having the formula in racemic form, enantiomerically enriched form or enantiomerically pure form, and pharmaceutically acceptable salts thereof. ... | 07/19/2011 |
| 7964223 | Berry preparations and extracts A method for deriving compositions having antioxidant and anti-inflammatory activity from berries is provided. The method results in a berry extract compositions having stable anthocyanin content. In one aspect, the method comprises exposing a berry to a solvent com... | 06/21/2011 |
| 7963398 | Method for hydraulically separating carbon and classifying coal combustion ash A method for selective separation of particles from a particle-containing material includes preparing a slurry of the particle-containing material and a dispersant, passing the slurry through a hydraulic classifier in a first direction, establishing a particle flow ... | 06/21/2011 |
| 7538194 | Genes encoding several poly (ADP-ribose) glycohydrolase (PARG) enzymes, the proteins and fragments thereof, and antibodies immunoreactive therewith The isolation and characterization of cDNAs encoding poly(ADP-ribose) glycohydrolase (PARG) enzymes and the amino acid sequences of PARGs from several species are described. PARG is involved in the cellular response to DNA damage and its proper function is associate... | 05/26/2009 |
| 7524946 | Nucleic acids encoding antigen and uses thereof The present invention provides novel isolated nucleic acids encoding antigenic proteins derived from Sarcocystis neurona, or unique fragments thereof. In particular, the invention provides novel isolated nucleic acids encoding membrane-associated polypeptides... | 04/28/2009 |
| 7521198 | Compositions and methods for detecting and treating atherosclerosis Methods for detecting atherosclerotic plaque and quantifying the amount of Group V sPLA2 in plasma are disclosed. These methods can be used to assess the risk of cardiovascular pathology in a patient. ... | 04/21/2009 |
| 7517967 | Monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma The present invention relates to monoclonal antibody 1A7. This is an anti-idiotype produced by immunizing with an antibody specific for ganglioside GD2, and identifying a hybridoma secreting antibody with immunogenic potential in a multi-step screening process. Also... | 04/14/2009 |
| 7517679 | Recombinant watermelon () hydroperoxide lyase and uses thereof Recombinant watermelon (Citrullus lanatus)hydroperoxide lyase protein, DNA sequences encoding the protein, vectors containing the DNA sequences and hosts containing the vectors are provided, together with methods for recombinantly producing watermelon hydrope... | 04/14/2009 |
| 7504078 | Continuous production of aligned carbon nanotubes An apparatus for continuous production of aligned carbon nanotubes is disclosed. The apparatus includes a reactor, an injector for delivering a feed solution into the reactor, and a conveyor for passing through the reactor a substrate on which nanotubes may be forme... | 03/17/2009 |
| 7501557 | Method utilizing the tobacco phylloplanin promoter for expression of nucleic acids as gene products directed to aerial surfaces of plants A method and system is provided for generating excreted gene products in a plant which includes generating a nucleic acid fusion construct comprising a phylloplanin promoter and a selected non-phylloplanin nucleic acid sequence whose transcription product is to be e... | 03/10/2009 |
| 7445923 | Crystallization and structure of a plant peptide deformylase This invention relates to the crystal structure of a plant peptide deformylase polypeptide and methods of using the structure to design compounds that modulate the activity of the polypeptide. ... | 11/04/2008 |
| 7440590 | System and technique for retrieving depth information about a surface by projecting a composite image of modulated light patterns A technique, associated system and program code, for retrieving depth information about at least one surface of an object. Core features include: projecting a composite image comprising a plurality of modulated structured light patterns, at the object; capturing an ... | 10/21/2008 |
| 7438904 | High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same A novel computational method and generation of mutant butyrylcholinesterase for cocaine hydrolysis is provided. The method includes molecular modeling a possible BChE mutant and conducting molecular dynamics simulations and hybrid quantum mechanical/molecular mechan... | 10/21/2008 |
| 7425319 | Method for enhancing protective cellular responses to genotoxic stress in skin The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses... | 09/16/2008 |
| 7423008 | Derivatives of mithramycin and methods of making and uses thereof The invention, in one aspect, generally relates to mithramycin derivatives from mutated Streptomyces argillaceus and their production. The invention also relates using the derivatives for the treatment of various diseases. Finally, the invention relates to a ... | 09/09/2008 |
| 7419604 | Use of boron compounds to precipitate uranium from water A method is provided for removing uranium from water. The method includes the mixing of a boron reagent with water contaminated with uranyl dication ions, leading to removal of the uranium from that water. ... | 09/02/2008 |
| 7419815 | Inhibitors of plant peptide deformylase for use as broad-spectrum herbicides and methods for identifying the same The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides. ... | 09/02/2008 |
| 7399849 | Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof The present invention provides a monoclonal anti-Idiotype antibody 11D10 that elicits an immune response against a specific epitope of a high molecular weight mucin of human milk fat globule (HMFG) and a hybridoma that produces 11D10. The hybridoma that produces 11D... | 07/15/2008 |
| 7385221 | Silylethynylated heteroacenes and electronic devices made therewith Novel silylethynylated heteroacenes and electronic devices made with those compounds are disclosed. ... | 06/10/2008 |
| 7385027 | Membrane-permeable peptide capable of calpain inhibition 5-mer peptides that can inhibit calpain I and calpain II are disclosed. The peptide sequence is as follows: Leu or Ala)-(Xaa)-(Asp or Glu)-(Xaa)-(Leu or Met), where Xaa can be any amino acid. ... | 06/10/2008 |
| 7368443 | 2,6-disubstituted piperidines and piperazine compounds The present invention is directed to 2,6-disubstituted piperidine and piperazine analogs having the following general formula: which are used to treat diseases of the central nervous system, drug abuse, and withdrawal there... | 05/06/2008 |
| 7364901 | Recombinant Stokesia epoxygenase gene A chimeric gene comprising an isolated nucleic acid molecule encoding a delta 12-fatty acid epoxygenase enzyme and transgenic plants containing the chimeric gene are described. Expression of the chimeric delta 12-epoxygenase gene leads to altered levels of fatty aci... | 04/29/2008 |
| 7345160 | Aequorin and obelin mutants with differing wavelengths and bioluminescence The invention relates to aequorin and obelin mutants whose emission is shifted with respect to wild type. The shift in emission is accomplished using a combination of mutations of amino acids within aequorin or obelin that affect bioluminescence; use of different ty... | 03/18/2008 |
| 7342100 | Hpr6 mutants and uses thereof Methods and agents that interfere with Hpr6 function in non-sarcoma tumor cells are disclosed. Anti-Hpr6 agents are used to enhance the killing effect of anti-cancer agents in non-sarcoma tumor cells and to teat non-sarcoma tumors. ... | 03/11/2008 |
