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| Number | Title | Issue Date |
| 7795182 | Method for making biochips A method for immobilizing biological polymers such as DNA or proteins, on a solid support, by ionocovalent bond, for making biochips, and the resulting chips obtained by the method. ... | 09/14/2010 |
| 7691864 | Anti-hypertensive composition and methods of treatment Pharmaceutical compositions for the treatment of hypertension comprising an effective anti-hypertensive amount of at least one compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, the compound having one of the fo... | 04/06/2010 |
| 7595023 | Spatiotemporal and geometric optimization of sensor arrays for detecting analytes in fluids Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array.... | 09/29/2009 |
| 7588773 | Methods and compositions for diagnosing and preventing a group B streptococcal infection The present invention provides a group B streptococcal (GBS) surface antigen, designated epsilon antigen, that is co-expressed with the delta antigen on a subset of serotype III GBS. Epsilon is expressed on more pathogenic Restriction Digest Pattern (RDP) III... | 09/15/2009 |
| 7572781 | Prodrugs for use as ophthalmic agents The subject invention provides a mechanism by which steroidal quinol compounds confer beneficial ophthalmic effects. The subject compounds possess a lipophilic-hydrophilic balance for transcorneal penetration and are readily reduced into parent phenolic A-ring stero... | 08/11/2009 |
| 7563613 | Detoxification and decontamination using nanotechnology therapy A method of removing a toxic compound comprising contacting the toxic compound with a particle having two regions, the first region containing a detoxifying enzyme and the second region containing a material selected to partition the toxic compound into the second r... | 07/21/2009 |
| 7534779 | Quinol compound and pharmaceutical composition The subject invention provides a mechanism by which steroidal quinol compounds confer beneficial ophthalmic effects. The subject compounds possess a lipophilic-hydrophilic balance for transcorneal penetration and are readily reduced into parent phenolic A-ring stero... | 05/19/2009 |
| 7423182 | Aminated polyamines An aminated polyamine having the formula: or its possible stereoisomers or a salt thereof with a pharmaceutically acceptable acid wherein: R1 and R4 may be the same o... | 09/09/2008 |
| 7202282 | Microemulsions for selective molecular separation The subject invention provides microemulsions having, as one component thereof, electron-deficient aromatic rings, e.g.. di(trifluoromethyi) benzene, for efficient separation and/or isolation of target molecules, e.g., bupivacaine. ... | 04/10/2007 |
| 7195780 | Nanoparticle delivery system The invention relates to the nanotubes of various sizes and composed of a wide variety of materials, or combination of materials. The invention also describes the use of such nanotubes for the delivery of various payloads and, in particular, for the in vivo delivery... | 03/27/2007 |
| 7186707 | Prodrugs for use as ophthalmic agents The subject invention provides a mechanism by which steroidal quinol compounds confer beneficial ophthalmic effects. The subject compounds possess a lipophilic-hydrophilic balance for transcorneal penetration and are readily reduced into parent phenolic A-ring stero... | 03/06/2007 |
| 7150125 | Insect attraction and capture device An apparatus particularly adapted for capturing target insect species comprising a bottom portion for attracting the target insects and directing them toward and into a top portion for the capture thereof. The bottom portion comprises a plurality of elements coopera... | 12/19/2006 |
| 7135674 | Method and apparatus for FAIMS with a laser-based ionization source A method of separating ions comprises applying a spot of a sample material to a target plate. The target plate is mounted in fluid communication with an ion inlet orifice of a FAIMS analyzer region and externally to the FAIMS analyzer region. Using a laser light sou... | 11/14/2006 |
| 7129343 | Bi-directional dual promoter complex with enhanced promoter activity for transgene expression in eukaryotes The present invention is directed to bidirectional promoter complexes that are effective for enhancing transcriptional activity of transgenes. The bidirectional promoters of the invention include a modified enhancer region with at least two core promoters on either ... | 10/31/2006 |
| 7122152 | Spatiotemporal and geometric optimization of sensor arrays for detecting analytes fluids Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array.... | 10/17/2006 |
| 7115566 | Compounds and method for the prevention and treatment of diabetic retinopathy The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridine⇄pyridinium salt-typ... | 10/03/2006 |
| 7090868 | Materials and methods for drug delivery and uptake The subject invention pertains to novel materials and methods for use in delivering and sequestering substances, such as pharmacological agents, within a patient. One aspect of the invention is directed towards core-shell particles having a core encapsulated within ... | 08/15/2006 |
| 7093179 | Method and coding means for error-correction utilizing concatenated parity and turbo codes A method and apparatus for encoding and decoding data using an overall code comprising an outer parity-check and an inner parallel concatenated convolutional, or turbo code. The overall code provides error probabilities that are significantly lower than can be achie... | 08/15/2006 |
| 7087106 | Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments The subject invention provides materials and methods for inhibiting the biofouling of surfaces exposed to aquatic environments. In one embodiment, the subject invention provides additives for marine paints and surface treatments. The subject invention further provid... | 08/08/2006 |
| 7051736 | Endotracheal tube pressure monitoring system and method of controlling same An endotracheal tube pressure monitoring system for an endotracheal tube having at least pressure sensor in communication with a major lumen of the endotracheal tube, and a pressure monitoring subsystem in operative communication with the pressure sensor. The system... | 05/30/2006 |
| 7049069 | Detecting and treating reproductive tract disorders Methods for detecting and treating a female reproductive tract disorder relate to the discovery that IL-13 and IL-15 are differentially expressed in biological samples from subjects suffering from a reproductive tract disorder compared to samples from healthy subjec... | 05/23/2006 |
| 7033815 | Biosynthesis of S-adenosylmethionine in a recombinant yeast strain The present invention makes use of a chimeric gene that, when incorporated into an appropriate host, results in the overproduction of S-adenosylmethionine without the need to supply the host with a source of untransformed methionine. The need for the methionine sour... | 04/25/2006 |
| 7034004 | Peptides and methods for the control of obesity The subject invention provides novel peptides for use in treating mammals to control appetite and obesity. Disclosed is a peptide derivative having the formula: X1-Z-Q-arg-trp-NH12 wherein: X1 | 04/25/2006 |
| 7024826 | Device for impeding a route of travel of crawling arthropods A barrier implement intended for obstructing a route of travel of crawling arthropods along a passageway comprises a sheet configured to circumscribe a passageway along which arthropods crawl. A dimension of the sheet is sized or molded relative to said passageway. ... | 04/11/2006 |
| 7018641 | Materials and methods for the control of plant pathogens The subject invention provides compositions useful for the control of plant pathogens. Specifically exemplified are essential oil compositions which are effective in the control of fungal and bacterial plant pathogens. ... | 03/28/2006 |
| 7012165 | Oxidative fluorination of aromatic and chloroaromatic derivatives The subject invention provides methods of fluorinating an aromatic or chloroaromatic compound comprising combining an aromatic compound, a chloroaromatic compound, a mixture of aromatic compounds, a mixture of chloroaromatic compounds, or a mixture of chloroaromatic... | 03/14/2006 |
| 7001616 | Microspheres for use in the treatment of cancer The subject invention pertains to novel materials and methods for use in treating patients afflicted with oncological disorders, such as tumors. One aspect of the invention concerns methods for treating tumors comprising the administration of drug loaded pH-sensitiv... | 02/21/2006 |
| 7001791 | GaN growth on Si using ZnO buffer layer A method for forming group III-N articles includes the steps of providing a single crystal silicon substrate, depositing a zinc oxide (ZnO) layer on the substrate, and depositing a single crystal group III-N layer on the ZnO layer. At least a portion of the group II... | 02/21/2006 |
| 6995015 | Pathogen-resistant grape plants The invention features a method of producing a grape somatic embryo having resistance to a plant pathogen, the method including the steps of (a) culturing a grape somatic embryo in a first liquid culture medium that includes a plant growth regulator and a phytotoxin... | 02/07/2006 |
| 6987564 | Automatic correction for continuum background in laser induced breakdown and Raman spectroscopy The approximation of a spectral continuum by determining a plurality of minima in the spectral data; splitting the spectral data into a predetermined number of groups N; for each group of spectral data, determining major minima for the group, and calculating an aver... | 01/17/2006 |
| 6979732 | Polynucleotide compositions encoding S-adenosyl-L-methionine:phosphoethanolamine N-methyltransferase and methods for modulating lipid biosynthesis in plants Disclosed are compositions and methods for increasing the nutritional value of plants and plant parts. In illustrative embodiments PEAMT and ΔPEAMT polynucleotide and polypeptide compositions are disclosed as well as their use in modulating the levels of lipid comp... | 12/27/2005 |
| 6977171 | Detoxification and decontamination using nanotechnology therapy A particle with two regions, the first region contains a detoxifying enzyme and a second region that partitions toxic compounds. The particle may be a nanoparticle. ... | 12/20/2005 |
| 6967084 | Kit for rapidly diagnosing upper respiratory conditions A kit for detecting upper respiratory conditions. The kit includes a container for collecting nasal secretions. The kit further comprises a means for providing a differential readout upon contact with the nasal secretions. ... | 11/22/2005 |
| 6960574 | Antagonists of RF-amide neuropeptides Disclosed are compounds having the formula: where R1=H, C1-C6 alkyl, cycloalkyl, R2... | 11/01/2005 |
| 6956023 | Materials and methods for providing nutrition to neonates The subject invention provides methods for reducing or preventing villous atrophy and feeding intolerance in infants, particularly low birth weight and/or preterm infants, by enterally administering granulocyte-colony stimulating factor (G-CSF), erythropoietin (Epo)... | 10/18/2005 |
| 6943145 | Compounds and method for the prevention and treatment of diabetic retinopathy The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridine pyridiniu... | 09/13/2005 |
| 6942854 | Orally-administered interferon-tau compositions and methods The present invention includes interferon-tau (IFNτ) pharmaceutical compositions useful for oral administration to treat cancers, autoimmune disorders (particularly multiple sclerosis), cell proliferative disorders and viral disease. ... | 09/13/2005 |
| 6924116 | Method for identifying cells Disclosed are silica-coated nanoparticles and a process for producing silica-coated nanoparticles. Silica-coated nanoparticles are prepared by precipitating nano-sized cores from reagents dissolved in the aqueous compartment of a water-in-oil microemulsion. A reacti... | 08/02/2005 |
| 6919484 | Method for incorporation of pentafluorosulfanyl (SF5) substituents into aliphatic and aromatic compounds The subject invention provides convenient, regiospecific and highly stereoselective addition of SF5Cl in high yield to a variety of alkenes and alkynes. ... | 07/19/2005 |
| 6919000 | Diffusion driven desalination apparatus and process A diffusion driven desalination apparatus and related method includes structure for receiving a heated water stream and creating at least one region having a thin film of water and structure for forcing a low humidity air stream over the thin film of water, wherein ... | 07/19/2005 |
