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| Number | Title | Issue Date |
| 7666581 | Methods for preparing compositions comprising heat shock proteins useful for the treatment of cancer and infectious disease The present invention relates to methods and compositions for the prevention and treatment of infectious diseases, and cancers. The methods of the invention comprises complexing a population of antigenic proteins or antigenic peptides derived from antigenic cells or... | 02/23/2010 |
| 7449557 | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy The present invention relates to complexes of alpha (2) macroglobulin associated with antigenic molecules for use in immunotherapy. The invention relates to methods for using such compositions in the diagnosis and treatment of immune disorders, proliferative disorde... | 11/11/2008 |
| 7186515 | Alpha(2) macroglobulin receptor as a heat shock protein receptor and uses thereof The present invention relates to the use of alpha (2) macroglobulin (“α2M”) receptor as a heat shock protein receptor, cells that express the α2M receptor bound to an HSP, and antibodies and other molecules that bind the α2M receptor-HSP complex. The inventio... | 03/06/2007 |
| 7179462 | α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof The present invention relates to the use of alpha (2) macroglobulin (“α2M”) receptor as a heat shock protein receptor, cells that express the α2M receptor bound to an HSP, and antibodies and other molecules that bind the α2M receptor-HSP complex. The inventio... | 02/20/2007 |
| 7132109 | Using heat shock proteins to increase immune response The present invention provides for a method of using heat shock proteins (HSPs) to amplify the immune response initiated by a vaccine. HSPs can be introduced into a subject before, concurrently, or after the administration of a vaccine. The HSPs can also be used to ... | 11/07/2006 |
| 6984389 | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M ... | 01/10/2006 |
| 6797480 | Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents The present invention relates to receptors for heat shock proteins (HSPs), such as gp96, Hsp70 and Hsp90. The heat shock receptor is associated with the cell membranes of a subset of antigen presenting cells, such as macrophages and dendritic cells. The present inve... | 09/28/2004 |
| 6451316 | Methods for generating antigen-reactive T cells in vitro The present invention provides methods for generating antigen-reactive T cells in vitro comprising priming immune cells and incubating the primed immune cells in vitro with a non-covalent complex of an heat shock protein and an antigenic molecule. The pre... | 09/17/2002 |
