Assignee: University Technology Corporation

Location: Boulder, CO
No. of patents: 84

Number	Title	Issue Date
7105852	High speed electron tunneling devices A detector includes a voltage source for providing a bias voltage and first and second non-insulating layers, which are spaced apart such that the bias voltage can be applied therebetween and form an antenna for receiving electromagnetic radiation and directing it t...	09/12/2006
6927285	Genes for human telomerase reverse transcriptase and telomerase variants The present invention is directed to novel telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa and 43 kDa t...	08/09/2005
6677309	Anti-cancer drug aldehyde conjugate drugs with enhanced cytotoxicity compounds, compositions and methods Monomeric and dimeric anti-cancer drug aldehyde conjugate compounds and pharmaceutically acceptable salts thereof. Specifically, monomeric and dimeric aldehyde conjugates of 1-2, dihetero-substituted anti-cancer drugs, including monomeric and dimeric alde...	01/13/2004
6565820	Low temperature oxidation using support molten salt catalysts Molten salt reactions are performed by supporting the molten salt on a particulate support and forming a fluidized bed of the supported salt particles. The method is particularly suitable for combusting hydrocarbon fuels at reduced temperatures, so that t...	05/20/2003
6501848	Method and apparatus for three-dimensional reconstruction of coronary vessels from angiographic images and analytical techniques applied thereto A method for in-room computer reconstruction of a three-dimensional (3-D) coronary vascular tree from routine biplane angiograms acquired at arbitrary angles and without using calibration objects. The method includes seven major steps: (1) acquisition of ...	12/31/2002
6497877	Plasminogen activator as an anti-inflammatory agent Plasminogen activator acts as an anti-inflammatory agent by inhibiting generation of superoxide anion by a mechanism that is not related to L-arginine, is not dependent on thrombolytic activity, and is not a function of oxygen free radical scavenging. Mor...	12/24/2002
6489450	High pressure refolding of protein aggregates and inclusion bodies The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield. The refolding takes place at pressures between about 0.25 ...	12/03/2002
6482435	Temperature sensitive gel for sustained delivery of protein drugs Pharmaceutical compositions for the delivery of pharmacologically active proteins are provided by the present invention. The compositions of the present invention comprise a polymeric matrix having thermal gelation properties in which is incorporated a di...	11/19/2002
6479007	Apparatus and method for controlling pore size in polymeric membranes and thin films An apparatus and method for controlling the pore structure of thin polymeric sheets, such as porous membranes and thin films, during solvent casting or interfacial polymerization. The invention may be used to reduce or eliminate macrovoid pore defects fro...	11/12/2002
6480299	Color printer characterization using optimization theory and neural networks A color management method/apparatus generates image color matching and International Color Consortium (ICC) color printer profiles using a reduced number of color patch measurements. Color printer characterization, and the generation of ICC profiles usual...	11/12/2002
6475789	Human telomerase catalytic subunit: diagnostic and therapeutic methods The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis, and tre...	11/05/2002
6444650	Antisense compositions for detecting and inhibiting telomerase reverse transcriptase The present invention provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions...	09/03/2002
6436636	Methods for identifying pharmacologicals for the treatment of heart failure Methods are disclosed for treating heart failure. Methods are disclosed for screening pharmacologicals that inhibit the down-regulatory activity of AUF1 or AUF1-related polypeptide for ଲ-adrenergic activity. Methods are disclosed for treating a pati...	08/20/2002
6417950	Three-color imaging on each pixel for increased resolution Apparatus for increasing color resolution and quality in digital imaging systems temporally modulates red, green and blue light, detects all three colors at each pixel, and band pass filters the detected light to extract values for red, green and blue at ...	07/09/2002
6403672	Preparation and use of photopolymerized microparticles Methods of forming polymer particles in situ from polymer precursors such as monomers or oligomers, comprising exposing a composition comprising at least one polymer precursor, a solvent or solvent mixture, and an antisolvent or antisolvent mixture to pho...	06/11/2002
6377202	Icing hazard avoidance system and method using dual-polarization airborne radar An icing hazard avoidance system and method utilizes a forward-looking, single frequency, dual-polarization pulse radar system as well as temperature sensing means to determine if supercooled liquid water (SLW) drops are present in an aircraft's flight pa...	04/23/2002
6377341	Refractive index based detector system for liquid chromatography An apparatus and method for on-column analysis in flash chromatography. The detection scheme utilizes refractive index changes as analytes move through an illuminated region of a chromatography column. The column packing material is a diffuse scattering m...	04/23/2002
6365164	Use of neurotoxin therapy for treatment of urologic and related disorders The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin....	04/02/2002
6356864	Methods for analysis and evaluation of the semantic content of a writing based on vector length The present invention is a methodology for analyzing and evaluating a sample text, such as essay(s), or document(s). This methodology compares sample text to a reference essay(s), document(s), or text segment(s) within a reference essay or document. The m...	03/12/2002
6353151	Transgenic model for heart failure The present invention discloses a transgenic mouse that is a model for congestive heart failure. The disclosed mouse is a subset of a transgenic mouse line that is a model for hypertrophic cardiomyopathy. Also disclosed are a recombinant nucleic acid mole...	03/05/2002
6325999	Use of Fas ligand to suppress T-lymphocyte-mediated immune responses A method for inhibiting T-lymphocyte-mediated immune responses, including those directed against autologous and/or heterologous tissues, e.g., by a recipient mammal of a transplanted tissue, said method comprising providing the recipient mammal with Fas l...	12/04/2001
6319521	Microparticles of lactide-co-glycolide copolymers and methods of making and using the same The present invention relates to the formation of microparticles from copolymers during a process involving precipitation with compressed antisolvents. The family of suitable copolymers have a semi-crystalline structure that above their glass transition t...	11/20/2001
6310673	Transmissive optical polarizing filters designed to maximize a desired portion of a spectral output This invention provides a complementary color polarizer using a single polarizing film followed by a stack of two or more retarders. In a preferred embodiment, the color polarizers of this invention produce orthogonally polarized complementary primary col...	10/30/2001
6309867	Telomerase The present invention is directed to novel telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa a...	10/30/2001
6268176	TRC8, a gene related to the hedgehog receptor, patched The present invention provides the sequence for a novel gene called TRC8 which is located on chromosome 8. Various types of alterations in the gene have been shown to be associated with renal and thyroid tumors. One such alteration involves a 3;8 transloc...	07/31/2001
6261836	Telomerase The present invention is directed to telomerase nucleic acids and amino acids. In particular, the present invention is directed to nucleic acid and amino acid sequences encoding various telomerase protein subunits and motifs, including the 123 kDa and 43 ...	07/17/2001
6254865	Method of treating huntington's disease using HNT neurons The present invention relates to methods and compositions for transplantation of neurons. The methods and compositions of the present invention provide a renewable supply of safe and effective therapeutic transplantable tissue. In particular, the present ...	07/03/2001
6245966	Adenoviral mediated gene transfer into lymphocytes The present application shows that the expression of Coxsackievirus and/or Adenovirus (CAR) in various lymphocyte cell lines is sufficient to facilitate the efficient transduction of these cells by adenoviruses. This property of CAR does not require its c...	06/12/2001
6232119	Immortalized human fetal neuronal cell line An immortalized line of human fetal brain cells capable of synthesizing dopamine has been developed. No tumor formation or rejection at 30 days post-transplantation has been detected. The cells are useful for transplantation therapy of a neurological defi...	05/15/2001
6228843	Method of using PKC inhibiting compounds to treat vascular disease A method for treating pulmonary and systemic vascular diseases associated with cardiac hypotrophy, dysfunction or failure that involves the administration of an effective amount of a PKC antagonist to a patient suffering from one of such diseases is discl...	05/08/2001
6225063	RNA channels in biological membranes The present invention provides nucleic acid molecules capable of binding phospholipid membranes, and more particularly RNA molecules capable of binding and forming channels in biological membranes. In this regard the present invention provides methods for...	05/01/2001
6225456	Ras suppressor SUR-5 The present invention relates to Ras suppressors, in particular the Ras suppressor SUR-5. The present invention provides isolated nucleotide sequence encoding SUR-5, isolated SUR-5 peptides, antibodies that specifically bind SUR-5, methods for the detecti...	05/01/2001
6224893	Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering Compositions for tissue engineering and drug delivery have been developed based on solutions of two or more polymers which form semi-interpenetrating or interpenetrating polymer networks upon exposure to active species following injection at a site in a p...	05/01/2001
6218597	Transgenic model and treatment for heart disease The invention provides a transgenic mouse that is a model for heart muscle disease and heart failure. Also provided are methods of using the transgenic mouse model to study heart muscle disease and heart failure and conditions and treatments related there...	04/17/2001
6219341	Method for bandwidth efficient multiple access wireless communication A method for wireless communication utilizes available channel bandwidth when multiplexing a plurality of user signals over a communication channel. The method utilizes signal power characteristics as a signature to multiplex and de-multiplex the pluralit...	04/17/2001
6203776	Method for identifying adrenergic receptor antagonists having good tolerability Disclosed are methods to identify adrenergic receptor antagonists having good tolerability. These methods include measuring the inverse agonist activity and/or the intrinsic sympathomimetic activity of an adrenergic receptor antagonist. Also disclosed are...	03/20/2001
6201638	Comb generating optical cavity that includes an optical amplifier and an optical modulator A low-loss comb-generating optical cavity including an optical amplifier and a microwave-driven electro-optic modulator crystal, produces a comb of optical frequency sidebands having spectral lines equally spaced around the frequency of an input laser bea...	03/13/2001
6169397	Damped superconducting coil system having a multiturn, planar geometry superconducting coil and shunt resistors electrically connecting successive coil turns The operation of a planar geometry superconducting coil used in conjunction with a ground plane is improved by intracoil damping. This damping reduces coil resonances. The improvement consists of an intracoil shunt, which damps the resonances of the coil ...	01/02/2001
6166178	Telomerase catalytic subunit The invention provides compositions and methods related to telomerase reverse transcriptase, the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of huma...	12/26/2000
6161435	Method and apparatus for determining the state of fouling/cleaning of membrane modules The fouling state of a polymeric membrane within the high pressure housing of a spiral wound or a hollow fiber membrane module is determined. An ultra sonic transducer positioned with its emitting face in physical engagement with the outer surface of the ...	12/19/2000

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Assignee: University Technology Corporation