Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 8182872 | Method of fabricating a porous elastomer A method is provided for fabricating a porous elastomer, the method comprising the steps of: providing a predetermined amount of a liquid elastomer and a predetermined amount of a porogen; mixing the liquid elastomer and the porogen in vacuum until a homogenous emul... | 05/22/2012 |
| 8170388 | Method for effective refractive index trimming of optical waveguiding structures and optical waveguiding structures A method for trimming an effective refractive index of optical waveguiding structures made for example in a high refractive index contrast material system. By compaction of cladding material in a compaction area next to patterns or ridges that are formed in the core... | 05/01/2012 |
| 8150272 | Systems and methods for transferring single-ended burst signal onto differential lines, especially for use in burst-mode receiver Systems and methods for transferring incoming single-ended burst signals of which at least one characteristic varies widely from burst to burst onto a pair of differential lines. The systems comprise an input for receiving an incoming burst signal, a signal adaptati... | 04/03/2012 |
| 8132218 | Access/edge node supporting multiple video streaming services using a single request protocol An access/edge network node (300) according to the invention includes a single proxy function (301) to terminate on the subscriber side a single requesting protocol for a plurality of streaming video services. ... | 03/06/2012 |
| 8039501 | Synephrine derivatives useful as anti-inflammatory agents This invention provides compounds having the structural formula: wherein: R1 is an acyl or sulfonyl group, R2 is an acyl group selected from the grou... | 10/18/2011 |
| 8026083 | and HAC1 nucleic acids Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metaboli... | 09/27/2011 |
| 7998485 | Sialoadhesin-related compositions and methods Methods of delivering a cargo moiety to a cell is provided according to embodiments of the present invention which includes contacting a cell expressing sialoadhesin with a conjugate including a sialoadhesin binding moiety and a cargo moiety. The sialoadhesin bindin... | 08/16/2011 |
| 7993822 | Aging biomarker The present invention relates to a marker that can be used as aging biomarker. More specifically, the present invention relates to the analysis of N-glycans in serum and its relation to the virtual age of the subject. This aging biomarker can be used to study the ef... | 08/09/2011 |
| 7893026 | Treatment of EGFR-dependent tumors by ABIN (a20 -binding inhibitor of NF kappab) The present invention relates to the treatment of epidermal growth factor-family receptor- (ErbB-) dependent tumors. More specifically, the present invention relates to the use of ABIN for the preparation of a medicament to inhibit epidermal growth factor- (EGF-) in... | 02/22/2011 |
| 7884125 | Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invent... | 02/08/2011 |
| 7846478 | Bioadhesive composition The invention provides bioadhesive composition having increased bioadhesive properties, decreased irritation, and the capacity for higher drug loading. The compositions of the invention comprise intimate mixtures of a polysaccharide and a polycarboxylated polymer, a... | 12/07/2010 |
| 7867490 | Treatment of liver cirrhosis and its complications The present invention relates to the field of liver diseases, more particularly to the field of portal hypertension and liver cirrhosis. The invention relates to the use of molecules which can inhibit the binding of placental growth factor (PIGF) to its receptor (VE... | 01/11/2011 |
| 7829758 | Modulation of plant cell number The present invention relates to the use of the ANG4 gene, or a variant thereof, to modulate the cell number of a plant organ. Said modulation can be used to increase the plant biomass, or to adapt the plant architecture. ... | 11/09/2010 |
| 7790143 | Vaccines for immunization against helicobacter The invention relates to the immunization of pigs against Candidatus Helicobacter suis using antigens of species related to Candidatus Helicobacter suis. ... | 09/07/2010 |
| 7569668 | Method to control tumor progression and invasiveness Described is a method of modulating E-cadherin mediated cell adhesion. More specifically, described is the use of hECRep1a and homologues thereof to modulate and/or control tumor cell invasiveness. ... | 08/04/2009 |
| 7566562 | Culturing circular ssDNA viruses for the production of vaccines The present invention relates to the use of interferon in the in vitro cultivation of animal circular ssDNA virus such as Porcine Circovirus 2 or human TT virus in an animal cell line. Increased titres of animal circular ssDNA virus are obtained by addition of inter... | 07/28/2009 |
| 7563881 | Nucleic acid encoding polypeptide involved in cellular entrance of the PRRS virus The present invention relates to a new polynucleotide that encodes a polypeptide involved in cellular entrance of PRRSV, to a recombinant vector comprising said polynucleotide, to a cell capable of expressing said polypeptide, a method of producing said polypeptide ... | 07/21/2009 |
| 7487587 | Methods of producing a composite substrate Methods of producing a composite substrate and devices made by the methods are disclosed. One of the methods comprises providing a flexible sacrificial layer, producing one or more patterned conducting layers on the flexible sacrificial layer, bending the sacrificia... | 02/10/2009 |
| 7432308 | Therapeutic compositions for the treatment of a respiratory tract disease The equilibrium between G actin and F actin is shifted towards the F actin confirmation with compounds such as the ionic form of magnesium or potassium. The higher amount of F actin decreases the inhibition of nucleases such as DNAse I by monomeric G actin. The incr... | 10/07/2008 |
| 7423113 | Leptin antagonist The present invention relates to an antagonist or inhibitor of leptin signaling via the leptin receptor. The leptin antagonist binds to the leptin receptor, but is unable to induce JAK-STAT signal transduction via the leptin receptor. By binding to the leptin recept... | 09/09/2008 |
| 7354412 | Orthopedic arm and shoulder brace The present invention relates to a portable device for providing continuous passive motion of a limb comprising a brace for supporting said limb. A programmable motor, mechanically connected to the brace, provides continuous passive motion of a limb. The movement of... | 04/08/2008 |
| 7347557 | Projector system comprising pulsed light sources A projection system comprising a light source is disclosed, wherein the light source comprises at least two light emitters arranged to be optically positionable alternately in a first position and a second position by an optical positioning means wherein said optica... | 03/25/2008 |
| 7335512 | Marker for measuring liver cirrhosis The invention provides methods and kits to detect liver cirrhosis in mammals. The diagnostic test is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. ... | 02/26/2008 |
| 7300785 | Culturing circular ssDNA viruses for the production of vaccines The present invention relates to the use of interferon in the in vitro cultivation of animal circular ssDNA virus such as Porcine Circovirus 2 or human TT virus in an animal cell line. Increased titres of animal circular ssDNA virus are obtained by addition of inter... | 11/27/2007 |
| 7264812 | vaccine The present invention relates to nucleic acid sequences encoding Ostertagia ostertagi proteins and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant ... | 09/04/2007 |
| 7244619 | Serum marker for measuring liver fibrosis The invention provides methods and kits to detect liver fibrosis or a change in the gradation of liver fibrosis in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. | 07/17/2007 |
| 7241611 | Methods for synthesis of holo-photoactive yellow protein The present invention is generally related to recombinant DNA technology and more particularly to DNA strands useful for the production of parahydroxycinnamic acid and photoactive yellow protein in a suitable host expression system. ... | 07/10/2007 |
| 7122656 | Splice variant of MyD88 and uses thereof The present invention relates to the field of infection and inflammation and, more specifically, to the field of pathogen-induced nuclear factor kappa B activation. More specifically, a novel splice variant of MyD88, (MyD88S), which has been identified en... | 10/17/2006 |
| 7056279 | Device and method for artificial insemination of bovines and other animals An artificial insemination (AI) device for the insemination of bovines and other animals including three hollow and essentially cylindrical tubular elements. Each element is provided with an open proximal and an open distal end, the three elements being: an outer pr... | 06/06/2006 |
| 7005123 | Functional poly-α-amino-acid derivatives useful for the modification of biologically active materials and their application A linear poly-α-amino-acid derivative has at least glutamic or aspartic or serinic repeating units and additionally having a functional group at one or both ends of the polymer backbone and/or only a single functional group as a side group on the polymer backbone, ... | 02/28/2006 |
| 6933328 | Composition of crosslinkable prepolymers for biodegradable implants A composition suitable for preparing a biodegradable implant, comprising a crosslinkable multifunctional prepolymer having at least two polymerizable end groups, the said composition having a viscosity such that it is deformable at a temperature of 0° to 60° C. in... | 08/23/2005 |
| 6930098 | Use of polysulphated cyclodextrins for treating osteoarthritis The present invention relates to the method of using polysulphated cyclodextrins or addition salts thereof for use in the treatment of arthrosis, and pharmaceutical compositions thereof. ... | 08/16/2005 |
| 6923984 | Cushioning wax beads for making solid shaped articles Biologically inactive cushioning beads comprise at least one compressible cushioning component consisting essentially of a microcrystalline hydrocarbon wax or a natural wax, the said wax being at least 30% by weight of the biologically inactive cushioning beads. Suc... | 08/02/2005 |
| 6824792 | Bioadhesive composition This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at least one natural or synthetic polycarboxylated polymer and at least on... | 11/30/2004 |
| 6731151 | Method and apparatus for level shifting A level-shifter architecture with high-voltage driving capability and extremely low power consumption, exploiting dynamic control of the charge on the gate electrodes of the high-voltage output transistors, is provided. The architecture can be integrated in CMOS tec... | 05/04/2004 |
| 6603605 | System for guiding a beam of electromagnetic radiation A system and method for guiding a beam of electromagnetic radiation is disclosed. The system includes at least a first stack of dielectric layers, the first stack comprising at least a first substack, a second substack and a third substack, the third subs... | 08/05/2003 |
| 6585557 | Beeswax mimetic substances and methods of operating beehives A beeswax mimetic substance is described which comprises or consists essentially of a synthetic or semisynthetic wax, in particular a microcrystalline wax. The wax preferably has a relatively narrow range of mean carbon chain length. An apiculture accesso... | 07/01/2003 |
| 6548327 | Low cost electroless plating process for single chips and wafer parts and products obtained thereof The present invention is related to a method for electroless plating Nickel/Gold on aluminium bonding pads of single chips or wafer parts. This method result in uniformly plated singulated chips, single dice or wafer parts in a much more simple and cost-e... | 04/15/2003 |
| 6436630 | Method for testing the toxicity of chemical substances using gastropods An in vivo and an in vitro toxicity test method is described using an organisim or part of an organism from the class Gastropoda. The method is particularly useful for toxicity testing of chemical substances intended for application to human or animal muc... | 08/20/2002 |
| 6132769 | Pharmaceutical matrix pellets, tablets and composition for the preparation thereof The present invention relates to pharmaceutical matrix pellet formulations providing an adequate drug release profile. The matrix of said pellets is formed from: (a) a hydrophilic compound selected among the group consisting of starch, a starch derivative... | 10/17/2000 |
