"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 6352862 | Analytical test device for imuno assays and methods of using same An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is fr... | 03/05/2002 |
| 6274324 | Specific binding reagent comprising a variable domain protein linked to a support or tracer Small specific binding molecules, such as single variable domain antibodies (Dabs) and Fv fragments, can be coupled to solid plastics surfaces or to tracers such as enzymes by means of linkers comprising polypeptides containing from 5 to 20 amino acids an... | 08/14/2001 |
| 6255115 | Agrobacterium mediated transformation of moulds, in particular those belonging to the genus Aspergillus The invention relates to Agrobacterium mediated transformation of moulds comprising species of the fungal sub-divisions Ascomycotina, Basidiomycotina, Deuteromycotina, Mastigomycotina, and Zygomycotina. Examples demonstrate the transformation of Aspergillus aw... | 07/03/2001 |
| 6204366 | Specific binding agents A reshaped human antibody or reshaped human antibody fragment having specificity for human polymorphic epithelial mucin (PEM) is produced by transferring the complementarity determining regions (CDRS) from a murine anti-HMFG hybridoma cell line HMFG1 into... | 03/20/2001 |
| 6159524 | Edible spread based on olive oil as the major fat component The present invention concerns the technical field of edible spreads. Consumers have exhibited a preference for fats which are relatively low in saturates, low in trans fatty acids, low in sixteen-carbon fatty acids and contain some polyunsaturated fats. ... | 12/12/2000 |
| 6140295 | Perfumed laundry detergents containing lipase The invention relates to laundry detergents containing lipase and new perfumes and to the new perfumes themselves. Such new perfumes counteract residual malodors of lipase treated laundry. They comprise at least 25% by weight of one or more fragrance mate... | 10/31/2000 |
| 6090574 | Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector A process is disclosed for preparing a protein by a eukaryote transformed by multicopy integration of an expression vector into the genome of a yeast, such as Saccharomyces, Hansenula, and Kluyveromyces, or of a mould such as Aspergillus, Rbizopus and Tri... | 07/18/2000 |
| 6004776 | Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector A process is disclosed for preparing a protein by a eukaryote transformed by multicopy integration of an expression vector into the genome of a yeast, such as Saccharomyces, Hansenula, and Kluyveromyces, or of a mould such as Aspergillus, Rhizopus and Tri... | 12/21/1999 |
| 5948894 | Immunoadsorbent reagents Improved affinity purification media are provided by the use of small specific binding agents, especially Fv antibody fragments or single domain antibody fragments, immobilised on porous carriers having pore sizes in the range 30-1000 angstroms, preferabl... | 09/07/1999 |
| 5804409 | Production of active Pseudomonas glumae lipase in homologous or heterologous hosts The production of an active Pseudomonas glumae lipase isolated from P. glumae PG1 (CBS 322.89) and other lipases suitable for application in detergent systems is described in homologous, but particularly in heterologous hosts, e.g. Bacillus subtilis. For ... | 09/08/1998 |
| 5801226 | Oral care compositions The present invention relates to novel monoclonal antibodies, raised against salivary pellicle, which are capable of recognising cryptitopes. They can be conjugated with a therapeutic or cosmetic active agent and can be targeted to the enamel pellicle or ... | 09/01/1998 |
| 5789010 | Malodors reduction The invention concerns a method of reducing the organoleptic effect of undesirable aldehydic components in a triglyceride or derivative thereof by addition of a reaction product of an amine and an organoleptically acceptable aldehyde. The triglyceride may... | 08/04/1998 |
| 5789212 | Process for producing gamma-lactomes The invention provides a process for producing gamma-lactones useful for incorporation in flavorings and fragrances, wherein a micro-organism which is acceptable for making food grade products and which does not metabolize gamma-lactones, is cultured aero... | 08/04/1998 |
| 5786442 | Polyester mixture, its preparation and use A polyester mixture is prepared composed of a diol, a dicarboxylic acid and optionally a monofunctional compound as a chain stopper, in which there is less than 3 wt. % of compounds having a molecular weight of up to 800. The process preferably involves s... | 07/28/1998 |
| 5783244 | Flavoring composition containing gamma-jasmolacton The invention relates to flavoring compositions characterized by an effective amount of gamma-jasmolactone having the formula ##STR1## as well as the use of these flavorings or gamma-jasmolactone per se for imparting, enhancing or improving the flavo... | 07/21/1998 |
| 5766656 | Fresh, renneted cast cheese and a method of manufacturing A fresh renneted cheese having a pH value of 6.7 or below and in particular between 6.0 and 5.0 having a hydrocolloid structure which has not developed before the casein network of the cheese has developed. A method of preparing this cheese comprises addi... | 06/16/1998 |
| 5711941 | Perfumed underarm hygiene products The invention concerns perfumed underarm hygiene products containing perfume encapsulated in a film forming encapsulation material showing improved re-encapsulating properties as evidenced by the "perfume re-encapsulation test. The underarm hygiene produc... | 01/27/1998 |
| 5698254 | Coconut cream alternative and method of preparing same The invention concerns coconut cream alternatives, being water continuous fat emulsions, comprising: 0.1-30wt. % vegetable fat, 0.1-5 wt. % protein compound, 0-2 wt. % emulsifier, 0-10 wt % sweetener, 0.01-5 wt. % thickener, 0.01-2 wt. % flavor, 0-1,500 p... | 12/16/1997 |
| 5696278 | Degumming of crude glyceride oils not exposed to prior enzymatic activity The present invention relates to a process for the preparation of degummed glyceride oils, which comprises applying an acid degumming treatment to a crude glyceride oil which has not substantially been exposed to enzymatic activity. Preferably such crude ... | 12/09/1997 |
| 5657762 | Method for monitoring ovulation A method of monitoring the ovulation cycle of a female mammal, involving regular measurement of basal body temperature throughout a current ovulation cycle and occasional measurement of the level of at least one urinary component of significance in the cy... | 08/19/1997 |
| 5643624 | Amorphous silicas An amorphous silica has a pore volume in the range of from about 1.6 to about 2.5 cc g-1, a mean pore diameter in the range of from about 8.0 to about 20 nm, a surface area in the range from about 450 to about 1100 m2 g-1 ... | 07/01/1997 |
| 5641671 | Production of active Pseudomonas glumae lipase in homologous or heterologous hosts The production of an active Pseudomonas glumae lipase isolated from P. glumae PG1 (CBS 322.89) and other lipases suitable for application in detergent systems is described in homologous, but particularly in heterologous hosts, e.g. Bacillus subtilis. For ... | 06/24/1997 |
| 5610077 | Processes and apparatus for carrying out specific binding assays A process for carrying out a specific binding assay by reacting (a) a sample under assay for the possible presence of a substance being tested for, (b) a specific binding partner for the substance being tested for, immobilised on a solid support, and (c) ... | 03/11/1997 |
| 5534341 | Emulsion binders Lofted non-woven materials are formed by bonding fibres and used for, e.g. furniture filing and heat insulation. The flammability of these materials is an important characteristic. The use of copolymer emulsions having defined Tg, molecular weight and sol... | 07/09/1996 |
| 5525709 | Process for the preparation of ceramides The invention relates to the preparation of ceramides by a two step process involving conversion of a 2-hydroximino-3-oxo-alkanoate into a 2-alkanoylamido-3-oxo-alkanoate intermediate by acylation of the oxime and reduction of the oxime ester group to an ... | 06/11/1996 |
| 5512266 | Aluminosilicates and detergent composition Aluminosilicates in the form of P type zeolites are used as detergency builders and have a silicon to aluminium ratio not greater than 1.33, preferably above 0.9. These zeolites will usually have a calcium binding capacity of at least 150 mg CaO per gram ... | 04/30/1996 |
| 5500223 | Encapsulating method and products containing encapsulated material An encapsulation process employs an aqueous dispersion of silica having a particle size not substantially greater than 100 nm. An emulsion is formed by high shear mixing of the silica dispersion with the material to be encapsulated and the emulsion is gel... | 03/19/1996 |
| 5447704 | Amorphous silica An amorphous silica, especially precipitated silica, suitable for use in toothpastes, has a high abrasivity represented by a perspex abrasion value in the range from about 23 to about 35.... | 09/05/1995 |
| 5420021 | Process for the preparation of -acetolactic acid The invention relates to a process for the production of -acetolactate and/or diacetyl, wherein a recombinant micro-organism containing an -acetolactate synthase-encoding sequence is incubated in a medium containing an -acetolactate p... | 05/30/1995 |
| 5405626 | Puff pastry laminates A baked composite dough product comprising a puff pastry dough sheet having attached thereto, at least at one side, a sheet of pastry dough which acts as an anchoring layer for a moisture-barrier coating which is applied on to the pastry layer after bakin... | 04/11/1995 |
| 5403741 | Apparatus and methods for microorganism culture and testing Processes and apparatus are provided for selectively culturing motile bacteria such as Salmonella, Camplylobacter, and others. One embodiment entails providing a carrier partly dipping into the liquid nutrient medium but projecting above a surface of the ... | 04/04/1995 |
| 5401527 | Process for preparing improved hydrolyzed protein The invention provides a process for improving HCl-hydrolysed protein by subjecting an aqueous solution thereof to hydrolysis (of monochloropropanediols and dichloropropanols) at a pH between 5.5 and 8.0 at a temperature between 20° and 180° C. for a pe... | 03/28/1995 |
| 5393507 | Silicate products The characteristics of compacted sodium silicate, in particular the bulk density, are improved by heating the material at an elevated temperature in an agitated bed. Bulk density in the region of 1 kg/liter can be obtained.... | 02/28/1995 |
| 5387511 | Extraction procedure for Chlamydia and Neisseria antigens Enhanced extraction of solubilized antigens is obtained from bacteria such as Chlamydia and Neisseri by the use of a buffer containing a zwitterionic surface active agent, especially CHAPS or CHAPSO, in the absence of divalent cations. The extraction is c... | 02/07/1995 |
| 5374370 | Type B aluminosilicates with low Si:Al ratio for detergent use Aluminosilicates in the form of P type zeolites are used as detergency builders and have a silicon to aluminium ratio not greater than 1.33, preferably above 0.9. These zeolites will usually have a calcium binding capacity of at least 150 mg CaO per gram ... | 12/20/1994 |
| 5366654 | Rinse aid compositions containing alkyl polycycloside and a ketone antifoaming agent Rinse aid compositions based on alkyl polyglycoside surfactants attack plastics, in particular polycarbonate, to a much lesser degree than rinse aid compositions based on other types of nonionic surfactants. It is preferred that the compositions also comp... | 11/22/1994 |
| 5364904 | Emulsion polymerization A copolymer emulsion suitable for use as a sizing agent for glass fibre is formed by microfluidising an emulsion containing at least 90% by weight of C1 to C10 alkyl(meth)acrylate monomer and stabilised by a protective colloid, e.g. polyvinyl alcohol, pri... | 11/15/1994 |
| 5364640 | Process for producing alkyl-methyl ketones The invention relates to a process for producing methyl-alkyl ketones using micro-organisms which convert fatty acids or their esters into the corresponding methyl ketones having one carbon atom less. Suitable micro-organisms are those which produce at le... | 11/15/1994 |
| 5360144 | Dispensing means for simultaneously dispensing two liquids Dispenser for dispensing simultaneously two liquids held in respective flexible containers, one within the other. Concentric tubular passages are provided for flows of the liquids from their containers when pressure is applied to the outer container. The ... | 11/01/1994 |
| 5358714 | Cosmetic composition A preserved composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical activator of protein kinase C enzymes chosen from diacylglycerols having the structure (1): ##... | 10/25/1994 |