...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 8183241 | 2-oxo-1-pyrrolidine derivatives The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. ... | 05/22/2012 |
| D660419 | Needle tip cap for a medication administration device | 05/22/2012 |
| 8178533 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. ... | 05/15/2012 |
| D657866 | Device for administering medication | 04/17/2012 |
| D653336 | Needle tip cap connector | 01/31/2012 |
| 8084638 | Sulfanyl derivatives and their use as synthesis intermediates The present application relates to sulfanyl derivatives of formula (I) and to their use as synthesis intermediates, especially for the preparation of the pharmaceutically active compound mesna. Formula (I), wherein X is O or N—C(NH)NH2; M+ is hydrogen, ... | 12/27/2011 |
| 8076493 | 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses The present invention relates to 3-carboxy-2-oxo-1-pyrrolidine derivatives of formula (I), geometrical isomers, enantiomers, diastereoisomers, pharmaceutically acceptable salts and all possible mixtures thereof, and processes using them. | 12/13/2011 |
| D649632 | Handle for a medication administration device | 11/29/2011 |
| D641078 | Medical syringe with needle tip cap | 07/05/2011 |
| 7964593 | Indolone-acetamide derivatives, processes for preparing them and their uses The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion. ... | 06/21/2011 |
| 7863450 | Compounds comprising an oxazoline or thiazoline moiety, processes for making them, and their uses The present invention relates to compounds comprising an oxazoline or thiazoline moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, (I), wherein A1 is CH C(CH3... | 01/04/2011 |
| 7790720 | Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses The present invention relates to compounds comprising an oxazole or thiazole moiety of formula (I), processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, Formula (I), wherein, A1 | 09/07/2010 |
| 7763644 | Imidazole derivatives, processes for preparing them and their uses The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. ... | 07/27/2010 |
| 7692028 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particul... | 04/06/2010 |
| 7645887 | Indolone-acetamide derivatives, processes for preparing them and their uses The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion. ... | 01/12/2010 |
| 7632856 | Indolone derivatives, processes for preparing them and their uses The present invention relates to indolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. ... | 12/15/2009 |
| 7619085 | Pyroglutamate salts and their use in the optical resolution of intermediates for the synthesis of dextrocetirizine and levocetirizine The present invention relates to (S)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide-(S)-pyrrolidone-5-carboxylic acid salt; (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide-(S)-pyrrolidone-5-carboxylic acid salt; (S)-2-[4-(4-chlorobenzhydryl)pi... | 11/17/2009 |
| 7612215 | Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation The present invention relates to a new process for preparing 2-oxo-1-pyrrolidine derivatives of general formula (I), comprising the cyclisation of an intermediate of general formula (II) wherein the substituents are as defined in the specification. | 11/03/2009 |
| 7563912 | Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues The present invention relates to an improved process for the preparation of (S)-(−)-α-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R | 07/21/2009 |
| 7531549 | Phenylalanine enamide derivatives Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted ... | 05/12/2009 |
| 7501437 | Phenylalanine enamide derivatives Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk—in which: Ar1 is an optionally substituted... | 03/10/2009 |
| 7488741 | 4-Aminopiperidine derivatives, processes for their preparation and their use as medicaments 4-Aminopiperidine derivatives, pharmaceutical compositions containing the same, and methods for their preparation are provided herein for the treatment of disorders of the central and/or peripheral nervous systems. In particular, the potent antidepressant activity s... | 02/10/2009 |