Assignee: Tsumura & Co.

Location: Tokyo, JP
No. of patents: 36

Number	Title	Issue Date
8182845	Ghrelin production promoter The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical i...	05/22/2012
8129192	Method for analyzing dithiocarbamate pesticide using microwave-assisted thermal digestion and extraction A method for analyzing a dithiocarbamate pesticide is provided. The method includes the steps of: adding a crude drug, a preparation containing the same, or a treated product thereof, an aqueous acid catalyst solution, L-cysteine or a salt thereof, and an organic so...	03/06/2012
7326427	Tablet composition containing Kampo medicinal extract and its manufacturing process A Kampo medicinal extract-containing tablet composition contains a Kampo medicinal extract powder, cellulose glycolate and sodium hydrogen carbonate. It preferably further contains silicic anhydride. A process to manufacture a Kampo medicinal extract-containing tabl...	02/05/2008
6313153	Compositions and methods for treating nephritis and inhibiting TGF -ଲ related conditions using pyridylacrylamide derivatives The present invention relates to an agent for treating nephritis and a TGF-ଲ inhibiting agent comprising as an effective ingredient a pyridylacrylamide derivative represented by the following formula (I): ##STR1## wherein Ar1 is a substit...	11/06/2001
6225478	Iridoid derivatives and neovascularization inhibitors containing the same as active ingredient Novel iridoid derivatives represented by general formula (I): ##STR1## and a vascularization inhibitor having for its active ingredient said derivative are disclosed. This vascularization inhibitor has remarkable vascularization inhibitory effects unaccom...	05/01/2001
6127519	Calcitonin derivatives Peptides useful in the regulation of calcium metabolism are disclosed. Also disclosed are pharmaceutical compositions of matter containing such peptides as well as a method for the regulation of calcium metabolism in a patient in need of such treatment. T...	10/03/2000
6054484	Transparent aqueous solution of diclofenac sodium and medicinal compositions with the use of the same Disclosed are a clear aqueous solution of diclofenac sodium dissolved in a mixed solvent of a fatty acid dialkylolamide and water; an anti-inflammatory analgesic composition excellent in percutaneous absorption, which comprises the clear aqueous solution ...	04/25/2000
6022888	Iridoid derivatives and neovascularization inhibitors containing the same as active ingredient Novel iridoid derivatives represented by general formula (I): and a vascularization inhibitor having for its active ingredient said derivative are disclosed. This vascularization inhibitor has remarkable vascularization inhibitory effects unaccompanied by...	02/08/2000
5968899	Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption Disclosed is a medicinal composition, which comprises a peptide as an effective ingredient and as bases, epsilon aminocaproic acid or tranexamic acid and an ethylene oxide-propylene oxide block copolymer represented by the following formula (I): HO(C...	10/19/1999
5795916	Composition of external preparation Disclosed herein is an external preparation composition, in a liquid preparation, cream, ointment or cataplasm plaster, characterized in that the composition contains a water-soluble salt of diclofenac, such as diclofenac sodium, water, and a fatty acid d...	08/18/1998
5734014	Elafin derivative Disclosed herein are elafin derivatives represented by an amino acid sequence of the following formula (I): ##STR1## wherein X represents leucine, isoleucine or valine, or represented by an amino acid sequence having homology to the first-mentioned a...	03/31/1998
5675023	Chromone derivative, and aldose reductase inhibitor comprising said compound as active component The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R1 and R2 each represent a ...	10/07/1997
5658265	Adaptor for connecting tubes to an animal Coaxial infusion pipes are disposed in a fixed shaft body and the ends of the pipes pass into a rotary shaft body. The fixed shaft body and the rotary shaft body are rotatably joined by bearings. Packings are provided inside the rotary shaft body in corre...	08/19/1997
5521216	Chromone derivative, and aldose reductase inhibitor comprising said compound as active ingredient The present invention relates to a chromone derivative of formula (1): ##STR1## (wherein R1 and R2 are the same or different and independently represent a hydrogen atom or a lower alkyl group) as well as a synthetic intermediate...	05/28/1996
5484595	Process for preparation of dibenzocyclooctadiene type lignan A dibenzocyclooctadiene type lignan can be efficiently prepared by extracting a plant containing a dibenzocyclooctadiene type lignan with a low polar solvent, subjecting the resulting extract to partition extraction with a water-insoluble low polar solven...	01/16/1996
5455267	Chromone derivative, and aldose reductase inhibitor comprising said compound as active component The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R1 and R2 each represent a ...	10/03/1995
5447719	ଲ-glucuronidase inhibitor A ଲ-glucuronidase inhibitor comprising at least one compound selected from the group consisting of baicalin, oroxylin A-7-O-glucuronide and luteolin-3'-glucuronide; an extract of scutellaria root (baikal skullcap; Scutellariae Radix) and/or schizone...	09/05/1995
5393740	Neurotensin Hexapeptides A hexapeptide represented by formula (II): A-B-Pro-C-D-E (I) where A represents an L- or D- form of arginine or lysine whose N-terminal amino group is alkylated or acylated, B represents an L- or D- form of argine, ...	02/28/1995
5374653	Iridoid derivatives and the use thereof as a drug Iridoid derivatives synthesized using genipin, which is an aglycon of geniposide, as the starting material are useful as an anti-hyperlipemia agent and as a cholagogue....	12/20/1994
5344845	Compound and use of the same as medicine Disclosed herein is a specific cinnamic acid derivative such as methyl 4-(4-acetoxy-3-methoxycinnamanide)-1-cyclohexanecarboxylate, or a pharmaceutically acceptable salt thereof. These compounds are useful as IV-type allergic reaction-suppressive drugs....	09/06/1994
5321135	Process for the preparation of polycyclic compounds using ferric perchlorate and acid trifluoroacidic Polycyclic compounds (I) can be prepared in accordance with the following reaction formula: ##STR1## wherein R1 -R8 each represents a hydrogen atom, a hydroxyl group, an alkoxyl group or a substituted or unsubstituted benzyloxy ...	06/14/1994
5318798	Process for producing kampo medicine hard capsules When a powdered extract of Kampo medicine is encapsulated as such in hard capsules, the pharmaceutical effects of the Kampo medicine cannot be fully achieved, since the dissolution of the content of the hard capsules requires a long period of time. Theref...	06/07/1994
5272172	Iridoid derivatives and the use thereof as a drug Iridoid derivatives synthesized using genipin, which is an aglycon of geniposide, as the starting material are useful as an anti-hyperlipemia agent and as a cholagogue....	12/21/1993
5264594	Biphenyl derivative and preparation and use thereof The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action and effective as a remedy for acute hepatitis and chronic hepatitis, a process for the preparation of this biphenyl derivative and a liver ailment-modera...	11/23/1993
5227398	Benzodioxole derivatives and hepatopathy improvers comprising the same Hepatopathy improvers contain as an effective ingredient one or more of benzodioxole derivatives represented by the following formula: ##STR1## wherein A means a particular N- or S-containing group. Most of these benzodioxole derivatives are novel....	07/13/1993
5214174	Platinum complex and anti-tumor agent comprising said complex as active ingredient Disclosed are a novel platinum complex represented by the following formula I or a steric isomer thereof, an anti-tumor agent comprising this complex as the effective ingredient, and a method of curing a tumor by using this complex: ##STR1## Thi...	05/25/1993
5106859	Certain 1,3,4-thiadiazole derivatives and anti-ulcer agent comprising said derivatives as active ingredient A novel thiadiazole derivative represented by the following formula I: ##STR1## wherein when n is 0, m is 0, and when n is 1, m is 0 or 1, and the preparation of this derivative and the use of this derivative as an anti-ulcer agent....	04/21/1992
5106871	Anti-ulcer agent comprising chalcone derivative as effective ingredient and novel chalcone derivative The present invention relates to an anti-ulcer agent comprising a compound represented by the following general formula I as the effective ingredient, and a novel chalcone derivative included in the compound represented by this general formula I: ##S...	04/21/1992
5041580	Novel binuclear platinum complex and antitumor agent comprising this complex as active ingredient Disclosed are a binuclear platinum complex including di-μ-sulfoacetato-bis[1,2-diaminocyclohexane-platinum (II)] and isomers thereof, and an antitumor agent comprising this complex as an effective ingredient. This complex has a high antitumor activity an...	08/20/1991
5026733	Brain function-improving medicine A brain function-improving medicine comprising, as an effective ingredient, a compound represented by the following formula: ##STR1## This medicine is effectively used for curing a disease caused by reduction of the central acetylcholinergic function...	06/25/1991
4996331	Novel biphenyl derivative and preparation and use thereof The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action and effective as a remedy for acute hepatitis and chronic hepatitis, a process for the preparation of this biphenyl derivative and a liver ailment-modera...	02/26/1991
4987240	Novel biphenyl derivative and production and use thereof The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action, which is effective for the remedy of liver diseases such as acute hepatitis and chronic hepatitis, a process for the preparation of this derivative and ...	01/22/1991
4962211	Novel biphenyl derivative and production and use thereof The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action, which is effective for the remedy of liver diseases such as acute hepatitis and chronic hepatitis, a process for the preparation of this derivative and ...	10/09/1990
4925872	Biphenyl derivative useful as a liver ailment moderating agent The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action and effective as a remedy for acute hepatitis and chronic hepatitis, a process for the preparation of this biphenyl derivative and a liver ailment-modera...	05/15/1990
4918107	Glutamate receptor inhibitor and insecticidal composition A compound of the formula ##STR1## wherein R' is hydrogen atom or an alkyl group, m is an integer of 1 to 3, p is 1 or 2, x is an integer of 2 to 6, and y is an integer of 1 to 3, or a salt thereof, which has glutamate receptor inhibitor activity, a ...	04/17/1990
4904694	Biphenyl derivative useful in the treatment of liver diseases The present invention relates to a novel biphenyl derivative having a liver ailment-moderating action, which is effective for the remedy of liver diseases such as acute hepatitis and chronic hepatitis, a process for the preparation of this derivative and ...	02/27/1990

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Assignee: Tsumura & Co.