...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 8177084 | Container assembly and pressure-responsive penetrable cap for the same A pressure-responsive container assembly and elastically-deformable penetrable cap is provided. Embodiments of the penetrable cap of the present invention include, but are not limited to: an annular sealing portion for engaging an inner surface of a container, a sub... | 05/15/2012 |
| 8076093 | Monoclonal antibodies and methods for their use in the detection of cervical disease Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM2. Monoclonal antibodies having the binding c... | 12/13/2011 |
| 8058404 | MCM6 and MCM7 monoclonal antibodies and methods for their use in the detection of cervical disease Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM6 or MCM7. Monoclonal antibodies having the b... | 11/15/2011 |
| 7989209 | Methods of chromogen separation-based image analysis Methods for chromogen separation-based image analysis are provided, with such methods being directed to quantitative video-microscopy techniques in cellular biology and pathology applications. ... | 08/02/2011 |
| 7940998 | System and method for re-locating an object in a sample on a slide with a microscope imaging device A method of re-locating an object in a sample is provided for a previously-scanned slide having determined objects each with corresponding stored coordinates and a stored image, the objects being mapped relative to each other. The slide is positioned on a microscope... | 05/10/2011 |
| 7899623 | Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis Methods and computer program products for evaluating and optimizing one or more markers for use in establishing a prognosis for a patient suffering from a disease are provided. More particularly, the methods include steps for systematically evaluating a number of fe... | 03/01/2011 |
| 7846692 | HE4 monoclonal antibodies and methods for their use Compositions and methods for diagnosing ovarian cancer in a patient and for identifying patients with an increased likelihood of having ovarian cancer are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specif... | 12/07/2010 |
| 7826650 | Method for quantitative video-microscopy and associated system and computer software program product A method of determining an amount of at least one molecular species in a sample from an image of the sample captured by an image acquisition device is provided, each molecular species being indicated by a dye. A dye space representation of a plurality of dyes is for... | 11/02/2010 |
| 7772535 | Method of capturing a focused image via an objective of a microscopy device A method of capturing a focused image of a continuously moving slide/objective arrangement is provided. A frame grabber device is triggered to capture an image of the slide through an objective at a first focus level as the slide continuously moves laterally relativ... | 08/10/2010 |
| 7632498 | MCM6 and MCM7 monoclonal antibodies and methods for their use in the detection of cervical disease Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM6 or MCM7. Monoclonal antibodies having the b... | 12/15/2009 |
| 7605356 | Apparatus and method for rapid microscopic image focusing A method of capturing a focused image of a continuously moving slide/objective arrangement is provided. A frame grabber device is triggered to capture an image of the slide through an objective at a first focus level as the slide continuously moves laterally relativ... | 10/20/2009 |
| 7602954 | Method for quantitative video-microscopy and associated system and computer software program product A method of determining an amount of at least one molecular species in a sample from an image of the sample captured by an image acquisition device is provided, each molecular species being indicated by a dye. A dye space representation of a plurality of dyes is for... | 10/13/2009 |
| 7595380 | Monoclonal antibodies and methods for their use in the detection of cervical disease Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM2. Monoclonal antibodies having the binding c... | 09/29/2009 |
| 7510838 | Methods and compositions for the detection of cervical disease Methods and compositions for identifying high-grade cervical disease in a patient sample are provided. The methods of the invention comprise detecting overexpression of at least one biomarker in a body sample, wherein the biomarker is selectively overexpressed in hi... | 03/31/2009 |
| 7455973 | Methods and compositions for the detection of cervical disease Methods and compositions for identifying high-grade cervical disease in a patient sample are provided. The methods of the invention comprise detecting overexpression of at least one biomarker in a body sample, wherein the biomarker is selectively overexpressed in hi... | 11/25/2008 |
| 7417213 | Apparatus and method for rapid microscopic image focusing having a movable objective A method of capturing a focused image of a continuously moving slide/objective arrangement is provided. A frame grabber device is triggered to capture an image of the slide through an objective at a first focus level as the slide continuously moves laterally relativ... | 08/26/2008 |
| 7157233 | Methods and compositions for the detection of cervical disease Methods and compositions for identifying high-grade cervical disease in a patient sample are provided. The methods of the invention comprise detecting overexpression of at least one biomarker in a body sample, wherein the biomarker is selectively overexpressed in hi... | 01/02/2007 |
| 7133547 | Method for quantitative video-microscopy and associated system and computer software program product A method of determining an amount of at least one molecular species in a sample from an image of the sample captured by an image acquisition device is provided, each molecular species being indicated by a dye. A dye space representation of a plurality of dyes is for... | 11/07/2006 |
| 7065236 | Method for quantitative video-microscopy and associated system and computer software program product A method of determining an amount of at least one molecular specie comprising a sample is provided, each molecular specie being indicated by a dye. The amount of the molecular specie is determined from an image of the sample captured as image data by a color image a... | 06/20/2006 |
| 6657003 | Cell adhesion solution A cell adhesion solution of a cross-linked polymer for substrates includes an amino acid polymer, a buffered cross-linking agent, and deionized water (DI H2 O). In one example, the amino acid polymer is selected from a neutral or basic amino ac... | 12/02/2003 |
| 6252979 | Interactive method and apparatus for sorting biological specimens An interactive process for sorting biological specimens includes the steps of processing a biological specimen to provide an analysis score, sorting the biological specimens according to the analysis score into categories including: clearly normal, intera... | 06/26/2001 |
| 6198839 | Dynamic control and decision making method and apparatus Dynamic control of the processing flow of an image analyzer such as a biological specimen analyzer as processing proceeds. Data collected and processed from a specimen under analysis, such as a biological specimen on a microscope slide, determines the fat... | 03/06/2001 |