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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8180458 | Method and apparatus for digital signal processing for radio frequency surgery measurements A method and apparatus for calculating current lost through a patient during a treatment of a patient using an electromagnetic energy delivery system is disclosed. The system generates electromagnetic energy, contacts a skin surface of the patient, transfers the ele... | 05/15/2012 |
| 8121704 | Leakage-resistant tissue treatment apparatus and methods of using same Apparatus and methods for treating skin conditions that deliver high frequency energy to a patient's tissue. The apparatus has a treatment tip configured to be removably coupled with a handpiece and a conduit inside the handpiece. The treatment tip includes an elect... | 02/21/2012 |
| 7957815 | Electrode assembly and handpiece with adjustable system impedance, and methods of operating an energy-based medical system to treat tissue Electrode assemblies and handpieces for energy-based treatment systems that utilize an impedance assembly to facilitate impedance matching between the system and a patient. The electrode assembly and/or handpiece may include one or more circuit elements configured t... | 06/07/2011 |
| 7481809 | Handpiece with RF electrode and non-volatile memory An RF device includes a support structure coupled to an RF electrode that has conductive and dielectric portions. A cooling member is coupled to the support structure and is configured to cool a back surface of the RF electrode. The cooling member is distanced from ... | 01/27/2009 |
| 7473251 | Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient A method of creating a tissue effect at a tissue site delivers electromagnetic energy through a skin surface from an electromagnetic energy delivery device coupled to an electromagnetic energy source. At least one of the electromagnetic energy delivery device or ele... | 01/06/2009 |
| 7452358 | RF electrode assembly for handpiece An RF device has a support structure. An RF electrode, coupled to the support structure, includes conductive and dielectric portions. A cooling member, coupled to the support structure, is configured to cool a back surface of the RF electrode. The cooling member is ... | 11/18/2008 |
| 7267675 | RF device with thermo-electric cooler An RF device includes a support structure. An RF electrode is coupled to the support structure and includes conductive and dielectric portions. A thermo-electric cooler is coupled to the support structure and is configured to cool a back surface of the RF electrode.... | 09/11/2007 |
| D544955 | Medical device tip | 06/19/2007 |
| 7229436 | Method and kit for treatment of tissue These and other objects of the present invention are achieved in a method for creating a desired tissue effect. An RF electrode is provided that includes a conductive portion. The RF electrode is coupled to a fluid delivery member that delivers a cooling fluidic med... | 06/12/2007 |
| 7189230 | Method for treating skin and underlying tissue A method for treating a tissue site couples an energy delivery surface of an electromagnetic energy delivery device with a skin surface. An underlying tissue area beneath the skin surface is created. The cooling creates a reverse thermal gradient, where a temperatur... | 03/13/2007 |
| 7141049 | Handpiece for treatment of tissue A handpiece that includes a handpiece assembly, a handpiece housing and a cooling fluidic medium valve member. An electrode assembly is coupled to the handpiece housing. The electrode assembly has a least one RF electrode that is capacitively coupled to a skin surfa... | 11/28/2006 |
| 7115123 | Handpiece with electrode and non-volatile memory An apparatus for cooling a skin surface includes an RF device that has an RF electrode with dielectric and conductive portions. The RF device is configured to be coupled to an RF energy source. A cooling member is coupled to the RF device. A memory is coupled to the... | 10/03/2006 |
| D527823 | Medical device pad | 09/05/2006 |
| 7022121 | Handpiece for treatment of tissue A handpiece has a handpiece assembly and includes a handpiece housing. An insert is detachably coupled to the handpiece housing. The insert includes an RF electrode with a conductive portion and a dielectric. ... | 04/04/2006 |
| 7006874 | Treatment apparatus with electromagnetic energy delivery device and non-volatile memory An apparatus for cooling a skin surface includes a support structure coupled to an electromagnetic energy delivery device. The electromagnetic energy delivery device is configured to be coupled to an electromagnetic energy source. A cooling member is coupled to the ... | 02/28/2006 |
| D506253 | Medical canister | 06/14/2005 |
| 6470216 | Method for smoothing contour irregularities of skin surface A method to modify a skin surface or a soft tissue structure underlying the skin surface includes a template with a mechanical force application surface and a receiving opening to receive a body structure. The mechanical force application surface is confi... | 10/22/2002 |
| 6461378 | Apparatus for smoothing contour irregularities of skin surface An apparatus to modify a skin surface or a soft tissue structure underlying the skin surface includes a template with a mechanical force application surface and a receiving opening to receive a body structure. The mechanical force application surface is c... | 10/08/2002 |
| 6453202 | Method and apparatus for controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and beco... | 09/17/2002 |
| 6438424 | Apparatus for tissue remodeling An apparatus to modify a skin surface or a soft tissue structure underlying the skin surface includes a template with a mechanical force application surface and a receiving opening to receive a body structure. The mechanical force application surface is c... | 08/20/2002 |
| 6430446 | Apparatus for tissue remodeling An apparatus to modify a skin surface or a soft tissue structure underlying the skin surface includes a template with a mechanical force application surface and a receiving opening to receive a body structure. The mechanical force application surface is c... | 08/06/2002 |
| 6425912 | Method and apparatus for modifying skin surface and soft tissue structure An apparatus is provided that modifies a skin surface or a soft tissue. The apparatus includes a skin surface conforming member and a hydration delivery device coupled to the conforming member. The hydration delivery device delivers a hydration agent to t... | 07/30/2002 |
| 6413255 | Apparatus and method for treatment of tissue An apparatus to treat the skin includes a template having a tissue interface surface and an energy delivery device coupled to the template. The energy delivery device is configured to be coupled to a power source and has a variable resistance portion. A s... | 07/02/2002 |
| 6405090 | Method and apparatus for tightening skin by controlled contraction of collagen tissue A method and apparatus for tightening a surface of a skin with an underlying collagen containing tissue applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epi... | 06/11/2002 |
| 6387380 | Apparatus for controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to an underlying subcutaneous layer or deeper soft tissue layers that includes loculations of fat with fibrous septae made of collagen tissue. This creates a desired contour effect without sub... | 05/14/2002 |
| 6381498 | Method and apparatus for controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane is adapted to receive an electrolytic solution and become infl... | 04/30/2002 |
| 6381497 | Method for smoothing contour irregularity of skin surface by controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane is adapted to receive an electrolytic solution and become infl... | 04/30/2002 |
| 6377855 | Method and apparatus for controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane is adapted to receive an electrolytic solution and become infl... | 04/23/2002 |
| 6377854 | Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane is adapted to receive an electrolytic solution and become infl... | 04/23/2002 |
| 6350276 | Tissue remodeling apparatus containing cooling fluid A fluid delivery apparatus for introducing a fluid cooling media to a skin surface includes a template with a skin interface surface. An energy delivery device is coupled to the template. A fluid cooling media introduction member is coupled to the templat... | 02/26/2002 |
| 6311090 | Method and apparatus for controlled contraction of collagen tissue A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and beco... | 10/30/2001 |
| 6241753 | Method for scar collagen formation and contraction A method is disclosed for forming and contracting scar collagen below a tissue surface in a selected tissue site. An electromagnetic energy apparatus is provided and includes an electromagnetic energy source and a delivery device. The delivery device is p... | 06/05/2001 |
