Celebrity Inventors
Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 7456203 | Muscarinic receptor antagonists Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscarinic recepto... | 11/25/2008 |
| 7456199 | Biphenyl compounds useful as muscarinic receptor antagonists This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined in t... | 11/25/2008 |
| 7452995 | Aryl aniline βadrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 11/18/2008 |
| 7452861 | Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent This invention is directed to methods of administering an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent having a substituent comprising at least about 8 carbon atoms. The invention is also directed to methods of using an echino... | 11/18/2008 |
| 7446114 | Quinolinone compounds as 5-HTreceptor agonists The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 re... | 11/04/2008 |
| 7427639 | β2-adrenergic receptor agonists Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.... | 09/23/2008 |
| 7419989 | Indazole-carboxamide compounds The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 recep... | 09/02/2008 |
| 7405199 | Cross-linked glycopeptide-cephalosporin antibiotics This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacteria... | 07/29/2008 |
| 7402673 | Diamine βadrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 07/22/2008 |
| 7399863 | Amino-substituted ethylamino βadrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 07/15/2008 |
| 7399862 | 5-HTreceptor agonist compounds The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 re... | 07/15/2008 |
| 7396933 | Quinolinone-carboxamide compounds The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 re... | 07/08/2008 |
| 7375181 | Process for purifying glycopeptide phosphonate derivatives Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a... | 05/20/2008 |
| 7375114 | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 re... | 05/20/2008 |
| 7368463 | Substituted 4-amino-1-benzylpiperidine compounds This invention provides 4-amino-1-benzylpiperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes ... | 05/06/2008 |
| 7358244 | Azabicycloalkane compounds This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, or a pharmaceutically acc... | 04/15/2008 |
| 7355046 | Biphenyl derivatives This invention provides biphenyl derivatives of formula I: wherein R1, R2, R3, R4, R5, R6, R7, W, a, b and c are as defin... | 04/08/2008 |
| 7351704 | Indazole-carboxamide compounds as 5-HTreceptor agonists The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 recep... | 04/01/2008 |
| 7351691 | Glycopeptide phosphonate derivatives Disclosed are glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial ... | 04/01/2008 |
| 7351791 | Intermediate for preparing glycopeptide derivatives This invention provides 9-fluorenylmethoxycarbonyl compounds that are useful as intermediates for preparing glycopeptide antibiotics. ... | 04/01/2008 |
| 7351718 | Substituted pyrrolidine and related compounds This invention is directed to compounds of formula I: wherein R1-R5 and a-e are as defined in the specification; or pharmaceutically-acceptable salt or solvate or stereoisomer ... | 04/01/2008 |
| 7351717 | Substituted pyrrolidine and related compounds This invention is directed to compounds of formula I: wherein R1-R5 and a-e are as defined in the specification; or pharmaceutically-acceptable salt or solvate or stereoisomer ... | 04/01/2008 |
| 7345060 | Compounds having βadrenergic receptor agonist and muscarinic receptor antagonist activity The invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7a, R7b, W, G1 | 03/18/2008 |
| 7345175 | Biphenyl derivatives This invention provides biphenyl derivatives of formula I: wherein R1, R2, R3, R4, R5, R6, R7, W, a, b and c are as defin... | 03/18/2008 |
| 7341993 | Cross-linked glycopeptide—cephalosporin antibiotics This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacteria... | 03/11/2008 |
| 7332471 | Cross-linked glycopeptide-cephalosporin antibiotics This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacter... | 02/19/2008 |
| 7329752 | Carbamate compounds as 5-HTreceptor agonists The invention provides novel benzoimidazolone-carboxamide-derived carbamate 5-HT4 receptor agonist compounds of formula (I): wherein R1, R2, R3, R4, a, and b... | 02/12/2008 |
| 7320990 | Crystalline form of a biphenyl compound The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of biphenyl-2-ylcarbamic acid 1-{9-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-quinolin-5 -yl)ethylamino]nonyl}piperidin-4-yl ester or a solvate thereof. This invention also provides pharmac... | 01/22/2008 |
| 7317023 | Diaryl ether β2 adrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 01/08/2008 |
| 7317022 | Benzoimidazolone-carboxamide compounds as 5-HTreceptors agonists The invention provides novel benzoimidazolone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 | 01/08/2008 |
| 7317102 | Diarylmethyl and related compounds This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, Ar1, Ar2, E, a, b, c and z are ... | 01/08/2008 |
| 7301004 | Process for preparing glycopeptide phosphonate derivatives Disclosed are processes for preparing glycopeptide phosphonate derivatives having an amino-containing side chain. Several of the process steps are conducted in a single reaction vessel without isolation of intermediate reaction products, thereby generating less wast... | 11/27/2007 |
| 7288657 | Biphenyl compounds useful as muscarinic receptor antagonists This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 ar... | 10/30/2007 |
| 7285564 | Substituted 4-amino-1-(pyridylmethyl)piperidine and related compounds This invention provides 4-amino-1-(pyridylmethyl)piperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; p... | 10/23/2007 |
| 7279458 | Cross-linked glycopeptide-cephalosporin antibiotics This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacter... | 10/09/2007 |
| 7265133 | Biphenyl compounds useful as muscarinic receptor antagonists This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as d... | 09/04/2007 |
| 7265086 | Glycopeptide carboxy-saccharide derivatives Disclosed are glycopeptide derivatives substituted at the C-terminus and/or the R-terminus with a substituent that comprises one or more saccharide groups and a carboxy group; and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed gl... | 09/04/2007 |
| 7262205 | Biphenyl compounds useful as muscarinic receptor antagonists This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, r, R1, R2, R3, R4, R5, R6, R7, and W are as defined in the... | 08/28/2007 |
| 7256294 | Crystalline form of a benzimidazole-carboxamide medicinal compound The invention provides crystalline forms of the novel benzimidazole-carboxamide 5-HT4 receptor agonist compound, 4-(4-{[(2-isopropyl-1H-benzoimidazole-4-carbonyl)amino]methyl}-piperidin-1-ylmethyl)piperidine-1-carboxylic acid methyl ester. The invention a... | 08/14/2007 |
| 7250414 | Diphenylmethyl compounds useful as muscarinic receptor antagonists This invention provides compounds of formula I: wherein a, b, c, e, m, n, Ar1, R1, R2, R3, R4a, R4b, R5 and R6 are as defined ... | 07/31/2007 |
