Famous Patents
British merchant Peter Durand invented the tin can in 1810.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5863555 | Buccal delivery of glucagon-like insulinotropic peptides Drug delivery systems and methods for administering a glucagon-like insulinotropic peptide to the buccal mucosa for transmucosal drug delivery are described. The drug delivery systems comprise a drug composition containing an effective amount of the gluca... | 01/26/1999 |
| 5849322 | Compositions and methods for buccal delivery of pharmaceutical agents A composition for transmucosally administering a drug to the oral cavity comprises an adhesive layer comprising a hydrophilic polymer having one surface adapted to contact a first tissue of the oral cavity and adhere thereto when wet and an opposing surfa... | 12/15/1998 |
| 5834010 | Triacetin as a penetration enhancer for transdermal delivery of a basic drug A composition and method for enhancing transdermal penetration of a basic drug are described. The composition comprises a matrix patch comprising an effective amount of a basic drug, preferably having a pKa of about 8.0 or greater, an effective... | 11/10/1998 |
| 5780050 | Drug delivery compositions for improved stability of steroids A stabilized patch device for transdermal drug delivery of steroid drugs containing a 3-keto-4-en functional group is described, wherein the patch comprises an effective amount of the steroid drug and a carrier that is free of acid functional groups. The ... | 07/14/1998 |
| 5762953 | Transdermal propentofylline compositions for the treatment of Alzheimers disease Patients suffering from Alzheimer's disease are treated by transdermally administering an effective amount of propentofylline in the form of an occulsive device containing a delivery composition comprising a carrier vehicle having uniformly distributed th... | 06/09/1998 |
| 5686094 | Controlled release formulations for the treatment of xerostomia A polymeric delivery system which is formed by a polycarbophil type composition with an active agent, optionally in the presence of water and/or other cosolvent. The resulting product is especially useful as a carrier or coating of active compositions, su... | 11/11/1997 |
| 5626866 | Drug-containing adhesive composite transdermal delivery device A method for making a transdermal drug delivery device for heat sensitive and volatile drugs is disclosed. The device contains a drug-containing adhesive composite layer having an impermeable backing material laminated to the distal surface thereof and a ... | 05/06/1997 |
| 5585464 | Recombinant antigen for diagnosing rheumatoid arthritis A method is described for diagnosing rheumatoid arthritis by providing a recombinant antigen (RAMA) and detecting rheumatoid arthritis-associated IgM antibodies against the RAMA antigen in patient sera. The RAMA antigen comprises SEQ ID NO:3 and peptides ... | 12/17/1996 |
| 5395753 | Method for diagnosing rheumatoid arthritis A method is described for diagnosing rheumatoid arthritis by providing a recombinant IgM-specific rheumatoid arthritis-associated antigen and detecting antibodies against the antigen in patient sera. Preliminary steps of making a cDNA library from polyade... | 03/07/1995 |
| 5227169 | Sorbitan esters as skin permeation enhancers Skin permeation enhancer compositions are provided which increase the permeability of skin to transdermally administered pharmacologically active agents. The compositions contain a sorbitan ester in addition to the selected pharmacologically active agent,... | 07/13/1993 |
| 5212199 | Sorbitan esters as skin permeation enhancers Skin permeation enhancer compositions are provided which increase the permeability of skin to transdermally administered pharmacologically active agents. The compositions contain a sorbitan ester in addition to the selected pharmacologically active agent,... | 05/18/1993 |
| 5164190 | Subsaturated transdermal drug delivery device exhibiting enhanced drug flux Transdermal administration of hydrophobic drugs via a diffusion mechanism in which the drug is dissolved in a carrier at concentrations that are 20% to 80% of the saturation concentration. The flux of drug from the device is non-Fickian and is substantial... | 11/17/1992 |
| 5152997 | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels Testosterone is administered transdermally through nonscrotal skin in a manner that mimics in amount and profile the natural production of testosterone in young adult healthy males. The testosterone is administered to the skin from a matrix which contains... | 10/06/1992 |
| 5122383 | Sorbitan esters as skin permeation enhancers Skin permeation enhancer compositions are provided which increase the permeability of skin to transdermally administered pharmacologically active agents. The compositions contain a sorbitan ester in addition to the selected pharmacologically active agent,... | 06/16/1992 |
| 5041292 | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents A biodegradable hydrogel matrix is provided, useful for the controlled release of pharmacologically active agents. The matrix is formed by cross-linking a proteinaceous component and a polysaccharide or mucopolysaccharide, and then loading a selected drug... | 08/20/1991 |
| 4888354 | Skin penetration enhancement using free base and acid addition salt combinations of active agents The invention is directed to compositions for topical application made up of active pharmaceutical permeants capable of existing in both free base and acid addition salt form. The permeants are present as a combination of both free base and acid addition ... | 12/19/1989 |
| 4863970 | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols Penetration-enhancing pharmaceutical compositions for topical transepidermal and percutaneous application are disclosed which are non-irritating to the skin. These compositions are made up of a safe and effective amount of an active pharmaceutical permean... | 09/05/1989 |
