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| Number | Title | Issue Date |
| 7994295 | Recombinant viruses comprising the membrane-proximal domain of VSV G protein Recombinant viruses, isolated nucleic acids and methods of generating same encoding for a Rhabdoviral G stem polypeptide are disclosed. Methods, compounds and compositions for target cell fusion potentiation mediated by Rhabdoviral G stem polypeptides, and applicati... | 08/09/2011 |
| 7182933 | Targeting drug/gene carriers to irradiated tissue The present invention provides a biomolecular carrier of pharmaceuticals, comprising: a biomolecule carrier bearing molecules that bind to a cellular adhesion molecule expressed on endothelial cell; and a pharmaceutical. The present invention also provides a method ... | 02/27/2007 |
| 7122823 | Thick clear crystal photostimulable phosphor plate for X-ray imaging A radiation imaging apparatus includes a photostimulable phosphor plate, an x-ray source, a red or infrared laser, and an array of photomultiplier tubes. The x-ray source propagates x-rays toward the plate, which is incident on the plate at a first incidence angle. ... | 10/17/2006 |
| 7071161 | Variants of corticotropin releasing hormone receptor Type 1 and uses thereof The present invention identifies four new isoforms of human corticotropin releasing hormone receptor type 1 (CRH-R1e, 1f, 1g and 1h) and three new isoforms of mouse corticotropin releasing hormone receptor type 1 (mCRH-R1c, 1e and 1f). The data indicate that polymor... | 07/04/2006 |
| 7041844 | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound. ... | 05/09/2006 |
| 7018816 | Real-time polymerase chain reaction-based genotyping assay for single nucleotide polymorphism The present invention provides fluorescence-based real-time PCR assays for the rapid detection of single nucleotide polymorphisms (SNPs). The genotyping assay can be used to detect SNPs of a number of genes of interest that include, but are not limited to, the human... | 03/28/2006 |
| 6995284 | Synthesis of selective androgen receptor modulators The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subc... | 02/07/2006 |
| 6737057 | Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors Immunomodulating agents comprising at least one Fc receptor ligand and at least one immunosuppressive factor are provided as are methods for their manufacture and use. The immunomodulating agents may be in the form of polypeptides or chimeric antibodies and preferab... | 05/18/2004 |
| 6730538 | Fabricating electronic devices using actinide oxide semiconductor materials A method for fabricating electronic devices. First, an actinide oxide semiconductor material is provided. Next, an electronic device is fabricated using the actinide oxide semiconductor material. ... | 05/04/2004 |
| 6660962 | Method for gas assisted energy beam engraving of a target object This invention relates to a method for gas assisted energy beam engraving of a target object. This invention employs and energy beam, such as a laser beam or an electron beam, to irradiate a target object in the presence of a selected gaseous environment ... | 12/09/2003 |
| 6638943 | Yohimbine dimers exhibiting binding selectivities for 댒 adrenergic receptors The present invention relates to yohimbine dimer compounds, pharmaceutical compositions containing such dimer compounds, methods of making such dimer compounds, and uses thereof. The yohimbine dimer compounds include compounds of formula (I): ##STR1#... | 10/28/2003 |
| 6632447 | Method for chemoprevention of prostate cancer This invention relates to the chemoprevention of prostate cancer and, more particularly, to a method of suppressing or inhibiting latent prostate cancer comprising administering to a mammalian subject a chemopreventive agent and analogs and metabolites th... | 10/14/2003 |
| 6627218 | Cationic amphiphiles of cholesterol A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a space... | 09/30/2003 |
| 6569896 | Selective androgen receptor modulators and methods of use thereof This invention provides a novel class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds which are tissue-selective androgen receptor modulators (SARM), which are useful for oral testosterone replacement therapy, m... | 05/27/2003 |
| 6498192 | Prevention of apoptosis in non-cancerous cells Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is obser... | 12/24/2002 |
| 6497873 | Recombinant Rhabdovirus containing a heterologous fusion protein This invention relates to a composition comprising a recombinant or genetically engineered Rhabdovirus that expresses a Fusion Protein, such as the F protein of the Paramyxovirus SV5 strain. This recombinant Rhabdovirus may express other non-Rhabdovirus a... | 12/24/2002 |
| 6492554 | Selective androgen receptor modulators and methods of use thereof The present invention relates to a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subclass of compounds which are sele... | 12/10/2002 |
| 6488859 | Bifunctional phenyl monophosphonic/sulfonic acid ion exchange resin and process for using the same A cross-linked water-insoluble ion exchange resin comprised of polymerized monomers having a phenyl ring is disclosed. A contemplated resin contains (i) polymerized phenyl ring-containing monomers having a phosphonic acid ligand linked to the phenyl ring,... | 12/03/2002 |
| 6482861 | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound.... | 11/19/2002 |
| 6481298 | Vehicle brake testing system This invention relates to a force measuring system capable of measuring forces associated with vehicle braking and of evaluating braking performance. The disclosure concerns an invention which comprises a first row of linearly aligned plates, a force bear... | 11/19/2002 |
| 6479595 | Plasma treatment of polymer materials for increased dyeability Hydrophobic polymer materials having improved dyeability with water-based dyes are prepared by treating a hydrophobic polymer with aglow discharge plasma generated from working gases selected from SO2, O2, N2, He, H2 | 11/12/2002 |
| 6456383 | Method and apparatus for making absolute range measurements This invention relates to a method and apparatus for making absolute distance or ranging measurements using Fresnel diffraction. The invention employs a source of electromagnetic radiation having a known wavelength or wavelength distribution, which sends ... | 09/24/2002 |
| 6448390 | Stable envelope proteins for retroviral, viral and liposome vectors and use in gene drug therapy This invention includes retrovirus envelope mutants into which heterologous peptide or glycopeptide sequences can be linked for expression and stable presentation on retroviral vectors. The envelope mutants are characterized by the ability to restore the ... | 09/10/2002 |
| 6428610 | Hepa filter The present invention is directed toward a filter media for a high efficiency particulate air ("HEPA") filter including a multiplicity of adjacent electrostatically charged piles of nonwoven fabric. The invention further includes a method of making a HEPA... | 08/06/2002 |
| 6423162 | Method for producing decorative appearing bumper surfaces This invention relates to a method of using a laser to produce a decorative appearance on the surface of a bumper. More specifically, the present invention relates to a laser alloying method to create a decorative alloyed layer on the surface of a bumper.... | 07/23/2002 |
| 6416633 | Resonant excitation method and apparatus for generating plasmas Two methods and corresponding electrode designs are provided for the generation of a plasma, for example, at or about one atmosphere. Using these methods, various webs, films and three-dimensional objects are beneficially treated in a reduced amount of ti... | 07/09/2002 |
| 6413533 | Method for chemoprevention of prostate cancer This invention provides the chemoprevention of prostate cancer and, more particularly, to a method of preventing prostate carcinogenesis comprising the steps of administering to a human subject having a precancerous precursor of prostate adenocarcinoma, a... | 07/02/2002 |
| 6413534 | Method for chemoprevention of prostate cancer This invention provides the chemoprevention of prostate cancer and, more particularly, to a method of preventing prostate carcinogenesis comprising the steps of administering to a human subject having a precancerous precursor of prostate adenocarcinoma, a... | 07/02/2002 |
| 6413535 | Method for chemoprevention of prostate cancer This invention provides the chemoprevention of prostate cancer and, more particularly, to a method of preventing prostate carcinogenesis comprising the steps of administering to a human subject having a precancerous precursor of prostate adenocarcinoma, a... | 07/02/2002 |
| 6410043 | Method for chemoprevention of prostate cancer This invention provides the chemoprevention of prostate cancer and, more particularly, to a method of preventing prostate carcinogenesis comprising the steps of administering to a human subject having a precancerous precursor of prostate adenocarcinoma, a... | 06/25/2002 |
| 6406759 | Remote exposure of workpieces using a recirculated plasma An OAUGD plasma is generated using, for example, paraelectric or peristaltic electrohydrodynamic (EHD) techniques, in the plasma generator of a remote-exposure reactor, wherein one or more active species, especially oxidizing species in the plasma are con... | 06/18/2002 |
| 6396590 | Process and system for determination of layer thickness swell of wood composites A process and system for obtaining a thickness swell measurement of a wood composite material sample. The process includes placing a measurement pattern on an edge of a wood composite material sample, the measurement pattern including layers having a thic... | 05/28/2002 |
| 6361791 | Stable aqueous dispersions including cationic lipids A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a space... | 03/26/2002 |
| 6357394 | Cage for housing dangerous animals A cage for housing animals, particularly for dangerous animals like venomous snakes, is disclosed. The cage has at least two compartments, one of which is an externally sealable drawer that can be removed from the cage by sliding it from the other compone... | 03/19/2002 |
| 6354157 | System for measuring load supplied to a platform The present invention relates to a system for measuring loads applied to a platform, wherein the accuracy of the measurements is not adversely affected by any moments or torques resulting from the application of the load to the platform. The present inven... | 03/12/2002 |
| 6353112 | Sultams: Solid phase and other synthesis of anti-HIV compounds and compositions Biologically active sultams are disclosed which have potent anti-HIV activity. A combinational method of synthesis, which uses a solid support and variants thereof, are described. Biological compositions and method of treating mammals for viral infections... | 03/05/2002 |
| 6328026 | Method for increasing wear resistance in an engine cylinder bore and improved automotive engine This invention is directed to a method for enhancing the wear resistance of an iron engine cylinder bore comprising laser alloying of the cylinder bore with selected precursors and honing the cylinder bore to a preselected dimension. The present invention... | 12/11/2001 |
| 6319516 | Acid salts of cholesterol A stable aqueous dispersion which comprises a cationic lipid which is a molecule which comprises a cholesterol-derived lipophilic group, a linker bond which is hydrolyzable by cellular enzymes and relatively resistant to base-catalyzed hydrolysis, a space... | 11/20/2001 |
| 6309851 | Method for producing a recombinant protein A method to inhibit the function of a class of bacterial periplasmic oxidoreductase enzymes, exemplified by TcpG of Vibrio cholerae, DsbA of E. coli, and Por of Haemophilus influenzae, is disclosed. A screening method to determine whether a chemical inhib... | 10/30/2001 |
| 6299707 | Method for increasing the wear resistance in an aluminum cylinder bore This invention is directed toward a method for enhancing the wear resistance of an aluminum cylinder bore comprising laser alloying of the cylinder bore with selected precursors. The present invention is particularly well suited for enhancing the wear res... | 10/09/2001 |
