Assignee: The University of Pittsburgh

Location: Pittsburgh, PA
No. of patents: 23

Number	Title	Issue Date
7851144	Compositions and methods for detecting cancer The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at ris...	12/14/2010
7776908	Wortmannin analogs and methods of using same Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well, as tumor formation in a subject are described herein. ...	08/17/2010
7446124	Wortmannin analogs and methods of using same in combination with chemotherapeutic agents Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic a...	11/04/2008
6974791	Endothelial specific targeting Peptide motifs which define specificity of tumor-derived endothelial cells. These peptides possess a charge motif of positive-positive-hydrophobic which is important in determining the specificity of binding to tumor-derived endothelium. The specific molecular pepti...	12/13/2005
6905667	Polymer and method for using the polymer for noncovalently functionalizing nanotubes A new, non-wrapping approach to functionalizing nanotubes, such as carbon nanotubes, in organic and inorganic solvents is provided. In accordance with certain embodiments, carbon nanotube surfaces are functionalized in a non-wrapping fashion by functional conjugated...	06/14/2005
6744727	Apparatus and method for spare capacity allocation A method is given for deriving a backup path routing spare capacity template that is feasible, scalable, adaptive, much faster, and near global optimal in redundancy reduction. The method includes determining working paths, aggregating the working paths into a first...	06/01/2004
6673937	Syntheses and methods of use of new antimitotic agents Oxidative cyclization of bis-naphthyl ethers allows concise total syntheses of palmarumycin CP1 and deoxypreussomerin A in 8-9 steps and 15-35% overall yield from 5-hydroxy-8-methoxy-1-tetralone. A small library of palmarumycin analogs was crea...	01/06/2004
6447265	Magnetically suspended miniature fluid pump and method of designing the same A rotary pump for pumping fluids through a patient having a housing with an internal region, a stator member and an impeller positioned within the housing and having impeller blades, wherein the impeller is magnetically suspended and rotated, and wherein ...	09/10/2002
6438419	Method and apparatus employing a scaling exponent for selectively defibrillating a patient A defibrillator, which selectively delivers a defibrillation pulse to a patient, includes electrodes adapted for placement on the patient, a monitoring circuit for providing an electrocardiogram (ECG) of the patient, and a defibrillation pulse generator h...	08/20/2002
6392055	Synthesis and biological evaluation of analogs of the antimitotic marine natural product curacin A The present invention provides an efficient synthetic strategy for the preparation of analogs that incorporate important structural elements of the marine natural product curacin A, the compositions and various uses of the compositions. The most active of...	05/21/2002
6224859	Composition containing immature mammalian dendritic cells for enhancing tolerogenicity to foreign graft A novel transplantation method for enhancing tolerogenicity in a host mammal to a transplant graft specimen from a donor mammal is disclosed. According to this method, immature mammalian dendritic cells propagated in the presence of a cytokine are adminis...	05/01/2001
6017699	PCR identification and quantification of important Candida species The subject invention relates to a set of DNA primers which, when utilized in conjunction with the polymerase chain reaction (PCR) assay, can amplify and speciate DNA from five medically important Candida species. Furthermore, the PCR amplified products, ...	01/25/2000
5876692	Non-lethal methods for conditioning a recipient for bone marrow transplantation The present invention relates to non-lethal methods of conditioning a recipient for bone marrow transplantation. In particular, it relates to the use of nonlethal doses of total body irradiation, total lymphoid irradiation cell type-specific antibodies, e...	03/02/1999
5869305	Recombinant viral vector system The present invention relates to a system for replication and encapsidation of recombinant DNA fragments into virus particles comprised of adenovirus associated viral (AAV) capsid proteins. The invention provides a means of obtaining recombinant viral sto...	02/09/1999
5774088	Method and system for warning birds of hazards A hazard warning system radiates pulses of microwave energy in the frequency range of 1 GHz to about 40 GHz to alert and warn target flying birds of the presence of wind turbine electrical generators, power distribution systems, aircraft, and other protec...	06/30/1998
5772994	Hematopoietic facilitatory cells and their uses The present invention relates to mammalian hematopoietic facilitatory cells (FC). In particular, it relates to the isolation, characterization and uses of the FC. The FC of the present invention can be distinguished from all other known bone marrow cells ...	06/30/1998
5714511	Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs A method for the treatment of mammalian tissue injured or at risk of injury during sepsis or shock including the administration to a mammal a diazeniumdiolate which releases a therapeutically effective amount of nitric oxide sufficient to protect the tiss...	02/03/1998
5501680	Boundary and proximity sensor apparatus for a laser A laser operation and control system preferably comprising a laser adapted to be grasped by a user and freely passed over a treatment area, control circuitry for activating and deactivating the laser, at least one boundary sensor operable to transmit a si...	03/26/1996
5221652	Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite for methanol synthesis The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination comprising reduced...	06/22/1993
5049347	Method for producing doubly oriented polymers A process for the solid phase preparation of doubly oriented synthetic polymeric material from an orientable amorphous but crystallizable or a semicrystalline thermoplastic polymeric workpiece comprising: (a) presenting the conditioned workpiece, at the e...	09/17/1991
4946938	A process for the catalytic synthesis of polyphosphazenes The present invention relates to an improved process for the synthesis of polyphosphazenes in which catalytic amounts of a compound selected from the group consisting of toluenesulfonic acid, sulfabenzoic acid, ammonium sulfamate and sulfamic acid, and pr...	08/07/1990
4883334	Optical selector switch The present invention pertains to an optical selector switch. The optical selector switch includes an optical waveguide means, and M means for producing light that can be transmitted through the optical waveguide means with M being greater than or equal t...	11/28/1989
4208399	Tolyl isocyanate test antigens, methods for their preparation and use in detecting diisocyanates and antibodies to diisocyanates An antigen and a method for its preparation and use in detecting antibody to a selected diisocyanate is provided by reacting the monoisocyanate derivative of the diisocyanate with a protein, incubating the antigen on a paper disc with test serum in the pr...	06/17/1980

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Assignee: The University of Pittsburgh