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Assignee: The University of Maryland


Location: CollegePark, MD
No. of patents: 35

NumberTitleIssue Date
7390832Dinuclear copper-based compound and ligand for nucleic acid scission and anticancer treatment
The present invention is related to a novel method for oxidizing or splitting nucleic acids at specific points on a complementary nucleic acid segment using a dinuclear copper-based compound of Formula I. Additionally, the present invention is related to a novel tre...
06/24/2008
7384772Chitin degradative systems
The present invention relates to chitin degradative systems, in particular to systems containing enzymes that bind to and depolymerize chitin. These systems have a number of applications. The present invention also describes enzymes with at least two catalytic domai...
06/10/2008
7371579Nickel-based reagents for detecting DNA and DNA-protein contacts
The invention relates to a compound comprising a labeled nickel complex (FIG. 1) that is used to detect and purify nucleic acid sequences by forming an adduct between a specific nucleic acid base and the labeled nickel complex. The adduct can also be purified...
05/13/2008
7358076Sublancin lantibiotic produced by 168
An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides which are at least 80% identical to the sublancin 168 peptide. T...
04/15/2008
7355074Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same
A compound containing at least two aromatic rings covalently bonded together, with each aromatic ring containing at least one oxyacetamide-based side chain, the compound being capable of forming a chloride ion channel across a lipid bilayer, and transporting chlorid...
04/08/2008
7268273Recovering metals from soil
The invention relates to recovering metals, such as nickel and cobalt, by phytomining or phytoextracting soils rich in metals wherein the desired metal is selectively accumulated in hyperaccumulator plants by adjusting the soil pH. The metals are ultimately recovere...
09/11/2007
7263357Method for fast roaming in a wireless network
A roaming service method for a fast and secure wireless network is provided. In an embodiment of the present invention, an AP, which an STA associates with, transmits security keys needed for roaming to neighbor APs of the AP. When the STA moves to one of the neighb...
08/28/2007
6694856Magnetorheological damper and energy dissipation method
Disclosed is a high-speed, high-force impulse load damper susceptible to adaptive control including a cylinder, a piston defining in the cylinder a volume, a coil, fixed relative to the cylinder, configured to generate a magnetic field, and a fluid channe...
02/24/2004
6492636Large scale high speed multiplexed optical fiber sensor network
A digital spatial and wavelength domain system for multiplexing fiber Bragg grating sensors comprises: a plurality of optical fibers, each including a plurality of fiber Bragg gratings therein, each fiber Bragg grating having a selective center wavelength...
12/10/2002
6471962Monoclonal antibodies for infectious bursal disease, vaccines and assays for use therewith
Two monoclonal antibodies which neutralize all infectious bursal disease viruses are employed in the preparation of infectious bursal disease vaccines. A panel of monoclonal antibodies can be used to characterize the infectious bursal disease virus strain...
10/29/2002
6153405Lantibiotic mutants and chimeras of enhanced stability and activity, leader sequences therefor, genes encoding the same, and methods of producing and using the same
Nisin-subtilin mutant and chimeric prepeptides were constructed and expressed in a Bacillus subtilis strain that possesses all of the cellular machinery for making subtilin, except for the presubtilin gene. The chimera SL -Nis1-11 -S...
11/28/2000
5871944Salmonellae preferential media
A new Salmonella preferential media uses lactose and cellobiose to suppress formation of black colonies by non-Salmonella, to permit easy inspection of the media to determine the presence or absence of Salmonella. Modified media, including high levels of ...
02/16/1999
5861275Lantibiotic mutants and chimeras of enhanced stability and activity, leader sequences therefor, genes encoding the same, and methods of producing and using the same
Nisin-subtilin mutant and chimeric pre-peptides were constructed and expressed in a Bacillus subtilis strain that possesses all of the cellular machinery for making subtilin, except for the pre-subtilin gene. The chimera SL -Nis1-11 ...
01/19/1999
5491060Mutant strain of E. coli for detection of methyltransferase clones
E. coli bacterial strains encoding a restriction gene that degrades methylated DNA, and prevents cloning of genes expressing the methyltransferase responsible for methylation, are mutated by a chemical or physical mutagen, so as to make the restriction en...
02/13/1996
5474933Marine melA gene
The present invention provides the isolated genes encoding marine melA from the genus Shewanella, especially from the species S. colwelliana, and the melA encoded thereby in homogeneous form. Further, the invention provides antibodies to marine melA as we...
12/12/1995
5347748Livestock walk-through fly trap
A walk-through fly trap for cattle and similar livestock is provided with a steel tubular frame on which is provided a roof and sides of pressure treated lumber. The sides support panels bearing electric grates, which grates are accessible to flying insec...
09/20/1994
5334537Direct immunoassay using pH-sensitive fluorochromes
The complexing of an antibody-antigen binding pair is determined by observing the change in fluorescence of a pH-sensitive fluorochrome attached to one of the members of the binding pair. When the binding is conducted in a solution having a pH other than ...
08/02/1994
5250413Sublethal bioassay for environmental quality
A sublethal assay is conducted to determine the presence of a stressor in the environment. An organism exposed to the environment is assayed for the presence of shock proteins, produced in response to environmental stress. The amount of stress protein can...
10/05/1993
5243837Subcooling system for refrigeration cycle
An improved subcooling system for nonazeotropic working fluid leaving a condenser in a multi-compartment system passes the fluid leaving the condenser in heat exchange relationship with fluid evaporating within the evaporator. The heat exchange relationsh...
09/14/1993
5235820Refrigerator system for two-compartment cooling
A refrigeration system for refrigerators having two or more compartments maintained at different temperatures comprises separate cycles for each compartment, each cycle in turn comprising separate evaporator means, heat exchanger means and compressor. To ...
08/17/1993
5224380Superconducting six-axis accelerometer
A superconducting six-axis accelerometer (SSA) for measuring the linear and angular acceleration of a superconducting proof mass in all six degrees of freedom at the same point in space time. The proof mass is formed of interlocking plates defining three ...
07/06/1993
5218101Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor
The method by which polypeptides having residues other than the 20 common amino acids are made is established. A leader peptide sequence, and its gene, are identified which induce or assist post-translational modifications of Cys, Thr and Ser in prokaryot...
06/08/1993
5212067Quick assay for detection of salmonella
A swift, accurate assay for the detection of salmonella contamination in a livestock environments, comprises sampling the floor of the livestock holding area with drag swabs for about 10 or more minutes, after which said swabs are maintained in a static c...
05/18/1993
5207077Refrigeration system
A dual evaporator refrigeration system cooling separate compartments at different temperatures employs specific combinations of environmentally safe refrigerants as working fluids. Each of the working fluids is a binary or ternary combination which yields...
05/04/1993
5208150Salmonella-Selective plating medium
An improved plating media incorporates TERGITOL.RTM.4, an alkyl sodium sulfate biological detergent, in a Xylose-lysine agar base. The plating media may also include peptone and sulfapyridine to further inhibit Citrobacter growth. The media is highly pref...
05/04/1993
5151164Enhanced capillary zone electrophoresis and apparatus for performance thereof
Capillary zone electrophoresis is enhanced by the application of an electric field across the interior of the capillary tube. This external electric field is applied through a conductive member at the exterior of the capillary tube. The external field vec...
09/29/1992
5149634Bioassay for environmental quality
A sublethal assay is conducted to determine the presence of a stressor in the environment. An organism exposed to the environment is assayed for the presence of shock proteins, produced in response to environmental stress. The amount of stress protein can...
09/22/1992
5133210Thermal expansion driven indentation stress-strain system
Disclosed is a method and apparatus of indentation testing of variable types of specimens which includes mounting an indenter member onto a thermally expandable member, mounting the specimen to be tested on a pedestal, loading the specimen with the indent...
07/28/1992
5092138Refrigeration system
A dual evaporator refrigeration system cooling separate compartments at different temperatures employ specific combinations of refrigerants as working fluids. Each of the working fluids is a binary combination which yields enhanced efficiency in the dual ...
03/03/1992
5064646Novel infectious bursal disease virus
A new virus not neutralized or bound by monoclonal antibodies which bind and neutralize all IBD vaccines of current art, and capable of inducing infectious bursal disease in poultry is identified, in essentially pure form. A test kit, and assay for the pr...
11/12/1991
5052736Modular dexterous hand
A modular dexterous grasping hand comprises three rotatable fingers mounted on the mounting plate of a Stewart platform for rotation about parallel axes extending perpendicular to the mounting plate. The fingers have a generally L shape so that the graspi...
10/01/1991
5018856Continuum source atomic absorption spectrometry
The instant invention relates to a process and apparatus for atomic absorption analysis, utilizing: atomization of a sample (containing one or more elements), illuminating the atomized sample with a continuum light source to produce a resultant light, dir...
05/28/1991
4985143Method for packing chromatographic beds
Column chromatography beds are packed through the application of static force. A slurry of the chromatography bed material and a non-viscous liquid is filled into the column plugged at one end, and allowed to settle. The column is transferred to a centrif...
01/15/1991
4956452Monoclonal antibody which neutralizes multiple strains of infectious bursal disease virus
Monoclonal antibodies effective in preventing infectious bursal disease in chickens, by neutralizing one or more virus strains thereof, have been isolated and obtained from deposited hybridomas. Vaccination of an entire poultry population with a vaccine p...
09/11/1990
4908305Competitive elisa for determination of neutralizing IBDV antibody
A method for determining the level of infectious bursal disease virus IBDV neutralizing antibody in poultry comprising a labeled monoclonal antibody R63 having the IBDV neutralizing capability of the monoclonal antibody expressed by hybridoma cell line AT...
03/13/1990
 
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