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| Number | Title | Issue Date |
| 7651770 | Nanoclusters for delivery of therapeutics The present invention discloses a nano-cluster that includes a plurality of nano-particles, wherein the nano-particles can disperse in response to an environmental cue. Also disclosed is a method of preventing, treating, or diagnosing a disease or condition in a sub... | 01/26/2010 |
| 7625878 | Sulfoalkyl ether-alkyl ether cyclodextrin derivatives A sulfoalkyl ether-alkyl ether cyclodextrin (SAE-AE-CD) derivative is provided. The SAE-AE-CD possesses advantages over known SAE-CD and AE-CD derivatives as well as over the parent cyclodextrin by being more water soluble and less membrane disturbing. The SAE-AE-CD... | 12/01/2009 |
| 7557757 | Inductively coupled feed structure and matching circuit for RFID device A feed structure (18) and matching circuit (20) for inductively coupling an antenna (16) with an IC (22) in an RFID tag (10). The tag (10) includes first and second feed structures (26,28) coupled with the antenna ( | 07/07/2009 |
| 7525724 | Laser system for photonic excitation investigation A laser system (10) for use in photonic excitation investigation of a target object, in which the target object interacts with incident photons and emits a corresponding photon which is detected and used to generate an image of the target object. The laser sy... | 04/28/2009 |
| 7505866 | Method of classifying data using shallow feature selection A method of classifying high-dimensional data to facilitate subsequent processing of the data. Generally characterized, the method includes determining a statistical distribution function for a first dataset; determining a statistical distribution function for a sec... | 03/17/2009 |
| 7505001 | Virtual short circuit for providing reference signal in RFID tag An RFID tag (10) including a virtual short circuit using a stepped impedance transformation from an open circuit or other known impedance point to provide a reference signal to an integrated circuit (22). The stepped impedance transformer (28) d... | 03/17/2009 |
| 7411002 | Polycationic sulfonamides and use thereof Certain lipophilic polycationic sulfonamides are provided and are useful for treating various diseases or conditions and particularly sepsis. ... | 08/12/2008 |
| 7308392 | Processes and systems for predicting biological species invasions Methods and systems are disclosed for predicting species invasions. Native species occurrence information and native environmental information are received. At least one ecological niche model is formulated based on the native species occurrence information and the ... | 12/11/2007 |
| 7199267 | Recognition of oligiosaccaride molecular targets by polycationic small molecule inhibitors and treatment of immunological disorders and infectious diseases Small molecule polycationic agents are used to modulate or interrupt biological processes by binding to oligosaccharide-based biomolecules. Compounds that inhibit nitric oxide, TNFα or other immunomodulators are provided and are useful for treating immunological di... | 04/03/2007 |
| 7199099 | Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria A means and method for treating bacterial infection, providing antioxidant activity, and chelating copper using a copper binding compound produced by methanotrophic bacteria is described. The compound, known as methanobactin, is the first of a new class of antibioti... | 04/03/2007 |
| 6937020 | Solid-state nuclear magnetic resonance probe A solid-state nuclear magnetic resonance probe that includes multiple sample spinning systems and detection coils is disclosed. The probe can be repositioned within the bore of the magnet to selectively maximize the throughput and sensitivity of the instrument by ac... | 08/30/2005 |
| 6924407 | Pressure-tuned solid catalyzed heterogeneous chemical reactions Improved methods for conducting solid acid-catalyzed, near- or supercritical heterogeneous chemical reactions (e.g., alkylation reactions) are provided which give enhanced product yields and permit longer processing runs. The preferred reactions of the invention are... | 08/02/2005 |
| 6740785 | Catalytic oxidation of organic substrates by transition metal complexes in organic solvent media expanded by supercritical or subcritical carbon dioxide Improved oxidation methods are provided wherein a reaction mixture comprising a substrate to be oxidized (e.g., phenols, alkenes) and an oxidation catalyst (typically dispersed in an organic solvent system) is supplemented with a compressed gas which expands the rea... | 05/25/2004 |
| 6697159 | Optical domain signal analyzer An Optical Domain Signal Analyzer, having an optical filter, a dispersive element and a detector is utilized to provide high resolution spectrum analysis over a wide optical bandwidth. The optical domain signal analyzer broadly includes an optical filter ... | 02/24/2004 |
| 6646623 | Three-dimensional display apparatus A three-dimensional display apparatus (10) that can be used to display conventional pseudo three-dimensional images and true three dimensional images using a CRT screen (96), or an array of digital micromirror devices (152) or an array of activated microm... | 11/11/2003 |
| 6599506 | D-form polypeptide that inhibits the interaction between LFA-1 and ICAM-1 Methods and compositions useful in inhibiting integrin-associated diseases are provided. The compositions contain a polypeptide having one or more D-amino acids that inhibit integrin binding to its associated binding polypeptide. The compositions include ... | 07/29/2003 |
| 6601010 | Force plate actometer A force plate actometer apparatus (30) is provided which is designed for the efficient and accurate testing of in vivo subjects (e.g., rats and mice) under the influence of drugs or other stimuli, and permits simultaneous determination of a number of attr... | 07/29/2003 |
| 6562952 | Precipitation of proteins from organic solutions A process for forming small micron-sized (1-10 μm) protein particles is provided wherein a protein, a solvent system for the protein and an antisolvent for the protein solvent system are contacted under conditions to at least partially dissolve the prote... | 05/13/2003 |
| 6457303 | Synthesis of epothilones Various epothilone precursors needed for the preparation of final epothilones are provided.... | 10/01/2002 |
| 6448454 | Catalytic oxidation of organic substrates by transition metal complexes in organic solvent media expanded by supercritical or subcritical carbon dioxide Improved oxidation methods are provided wherein a reaction mixture comprising a substrate to be oxidized (e.g., phenols, alkenes) and an oxidation catalyst (typically dispersed in an organic solvent system) is supplemented with a compressed gas which expa... | 09/10/2002 |
| 6395685 | Thin film Hg-based superconductors, thermoelectric materials and methods of fabrication thereof Improved Hg-containing superconducting films and thermoelectric materials are provided. The films are fabricated by annealing starting Tl-containing films (e.g., Tl-1212 or Tl-2212) in an Hg-vapor environment so as to cause a substitution of Tl by Hg with... | 05/28/2002 |
| 6380276 | Metal complexes immobilized in porous organic hosts Polymer-metal ion composites and methods are provided for reversibly binding target compounds using such composites. Broadly, the composites comprise an amorphous polymer matrix having a plurality of channels with metal ion-ligand complexes immobilized th... | 04/30/2002 |
| 6246803 | Real-time feature-based video stream validation and distortion analysis system using color moments A real-time distortion analysis system (20) utilizes a baseline preparation processor (38) and a remote comparison processor (50) to determine (72, 78) a plurality of color and central moments for baseline and broadcast video streams respectively. The bas... | 06/12/2001 |
| 6211412 | Synthesis of epothilones Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment C using a stereoselective Noyori-type reduction, and t... | 04/03/2001 |
| 6113795 | Process and apparatus for size selective separation of micro- and nano-particles Processes and apparatuses are provided for continuously harvesting particles from organic solution-laden near-critical and supercritical fluids. Broadly, the processes and apparatuses utilize a filter or separator comprising a thin membrane supported on a... | 09/05/2000 |
| 6100428 | Nickel promoted guanylation of amines with isothioureas and thioureas An improved method for guanylating amines is provided. Broadly, the amines are reacted with a guanylating agent in the presence of a nickel catalyst. Preferably, the nickel catalyst comprises nickel in the zero oxidation state. Suitable nickel(0) catalyst... | 08/08/2000 |
| 6075004 | Peptide compositions which induce immune tolerance and methods of use Peptide compositions which inhibit the binding of one protein to another protein, and corresponding methods of use are disclosed. These peptide compositions include at least one peptide which binds to one protein, and at least one peptide which binds to t... | 06/13/2000 |
| 6005608 | Three-dimensional display apparatus A three-dimensional display apparatus (10) for displaying true three-dimensional images that can be viewed without special three-dimensional eye glasses is disclosed. The apparatus includes a screen (12), a screen moving assembly (14) for moving the scree... | 12/21/1999 |
| 5907075 | Solid acid supercritical alkylation reactions using carbon dioxide and/or other co-solvents Improved isoparaffin-olefin alkylation solid catalyst processes are provided which are characterized by low coke laydown and catalyst deactivation rates and production of valuable branched chain, high octane number alkylates. The processes of the inventio... | 05/25/1999 |
| 5883050 | Hg-based superconducting cuprate films A Hg-based superconducting cuprate film on a substrate is disclosed, which comprises a compound having the formula Hg1-x Mx Ba2 Can-1 Cun Oy, M is a metal cation, x ranges from 0 to 1, n is... | 03/16/1999 |
| 5874029 | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent A method and an apparatus useful for the production of microparticles and nanoparticles are disclosed in which a compressed fluid and a solution including a solvent and a solute are introduced into a nozzle to produce a mixture. The mixture is then passed... | 02/23/1999 |
| 5863889 | ICAM-1/LFA-1 short-chain peptides and method of using same Short-chain peptides replicating fragments of functional domains derived from LFA-1 and ICAM-1 parent protein sequences serve to modulate the ICAM/LFA binding interaction. In one aspect of the invention, this modulation serves to block interprotein bindin... | 01/26/1999 |
| 5843885 | ICAM-1/LFA-1 short-chain peptides and method of using same Short-chain peptides replicating fragments of functional domains derived from LFA-1 and ICAM-1 parent protein sequences serve to modulate the ICAM/LFA binding interaction. In one aspect of the invention, this modulation serves to block interprotein bindin... | 12/01/1998 |
| 5843870 | Alkaline-doped mercury cuprate superconductors Alkaline-doped superconductors of the formula X M2 Ca2 Cu3 O8+ are provided where X is selected from the group consisting of TI, Pb, Mo, Hg and mixtures thereof, M is selected from the group consisting of Ba, Sr ... | 12/01/1998 |
| 5833891 | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents Improved methods and apparatus for particle precipitation and coating using near- or supercritical fluid conditions are described. A fluid dispersion having a continuous phase dispersant and at least one precipitatable substance therein is contacted with ... | 11/10/1998 |
| 5717416 | Three-dimensional display apparatus A display apparatus operable for displaying actual three-dimensional moving images is provided. The display apparatus includes a stepper motor having an elongated rotatable shaft, a plurality of display structures spaced along the length of the rotatable ... | 02/10/1998 |
| 5710356 | Method of conducting an endothermic reaction in a packed-bed reactor with external energy addition A novel, packed-bed, reverse flow reactor is provided for the endothermic dehydrogenation of ethylbenzene to styrene. The catalyst bed is flanked by inert end sections to prevent the occurrence of the reverse reaction. Ethylbenzene vapor is added at one e... | 01/20/1998 |
| 5672584 | Cyclic prodrugs of peptides and peptide nucleic acids having improved metabolic stability and cell membrane permeability Provided are cyclic prodrugs of biologically active peptides and peptide nucleic acids exhibiting improved cell membrane permeability and enzymatic stability, containing 3-(2'-hydroxy-4',6'-dimethyl phenyl)-3,3-dimethyl propionic acid and its deriveatives... | 09/30/1997 |
| 5576186 | Diagnosis and monitoring of rheumatological diseases by detection of anti-EF1- antibodies A method and assay kit are provided for diagnosing systemic lupus erythematosus by detecting a concentration of anti-EF-1 antibodies that may be found within a sample of body fluid. The assay employs substantially pure EF-1 antigen, which is... | 11/19/1996 |
| 5470821 | Superconductors having continuous ceramic and elemental metal matrices Composite bulk superconducting materials having desirable physical, measured transport current density and high Tc superconducting characteristics are provided which comprise a first matrix of superconducting ceramic oxide crystalline grains wi... | 11/28/1995 |
