Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 8167087 | Multimodal indicator safety device for ladder positioning A safety device for measuring and indicating the level of a ladder having rungs extending between a pair of elongated ladder rails, the safety device comprising a housing dimensioned to be inserted into one of the rungs of the ladder, an electronic sensor disposed i... | 05/01/2012 |
| 8148057 | Methods, immunoassays and devices for detection of anti-lipoidal antibodies Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, a method for immobilizing a lipoidal antigen, comprising cardiolipin, lecithin, and cholesterol, on a s... | 04/03/2012 |
| 8119788 | Compositions and methods for the detection of species Compositions and methods for detecting and/or differentiating among Candida organisms, including C. albicans and C. dubliniensis, are disclosed. Exemplary methods involve screening a sample suspected of containing at least one or more Candida... | 02/21/2012 |
| 8105609 | Flavivirus immunogens comprising extracellular viral particles composed of the premembrane (prM) and envelope (E) antigens The invention encompasses nucleic acid molecules containing transcription units which encode the flavivirus M and E protein antigens. The flaviviruses include Japanese encephalitis virus, dengue, yellow fever virus and St. Louis encephalitis virus. The nucleic acids... | 01/31/2012 |
| 8043809 | Real-time PCR point mutation assays for detecting HIV-1 resistance to antiviral drugs Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding the reverse transcriptase or protease of HIV as disclosed herein. Thus, provided is an oligonucleotide comp... | 10/25/2011 |
| 7906292 | Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use Disclosed herein is a method for identifying flavivirus cross-reactive epitopes. Also provided are flavivirus E-glyco-protein cross-reactive epitopes and flavivirus E-glycoprotein crossreactive epitopes having reduced or ablated cross-reactivity... | 03/15/2011 |
| 7871779 | Molecular identification of species Novel techniques for the detection of Aspergillus in samples are disclosed. These techniques relate to PCR amplification and/or detection of Aspergillus ITS1 rDNA sequences, and the identification of particular species of Aspergillus by detectin... | 01/18/2011 |
| 7863041 | Rabies virus vector systems and compositions and methods thereof Rabies Virus compositions and methods are provided. The full-length sequence of Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) is disclosed. A reverse genetics system for producing recombinant ERA virus and derivatives thereof is provided, along with compositi... | 01/04/2011 |
| 7776521 | Coronavirus isolated from humans Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, a... | 08/17/2010 |
| 7727765 | Method for leak testing an environmental enclosure Methods and apparatus are disclosed for leak testing the ventilation system of an environmental enclosure using a gas that is naturally present in ambient air, such as nitrogen, oxygen, argon, or carbon dioxide, as a tracer gas. In one embodiment, a gas filter capab... | 06/01/2010 |
| 7595059 | Methods and compositions for detecting larval with a cloned diagnostic antigen Compositions and methods for the detection of Taenia solium and the diagnosis of T. solium infection are described. The nucleotide and amino acid sequences of the antigenic T. solium polypeptides gp50a, gp50b and gp50c are p... | 09/29/2009 |
| 7469186 | Finding usable portion of sigmoid curve Various technologies are described by which the usable portion or threshold value of a sigmoid curve is found. Such techniques can be useful, for example, when determining the concentration or presence of a substance in a test sample. Various techniques can avoid va... | 12/23/2008 |
| 7425611 | Immunogenic HIV-1 multi-clade, multivalent constructs and methods of their use Described herein are nucleic acid molecules which encode multiple highly conserved epitopes from HIV-1 proteins, and optionally also epitopes from CCR5; usually also included sequences that encode spacers between two or more of the epitopes. Some of the provided nuc... | 09/16/2008 |
| 7407664 | Peptide vaccines against group A streptococci This invention, in one aspect, relates to synthetic immunoreactive peptides. These peptides are approximately 20-25 amino acids in length which are portions of the N termini of the M proteins of the most prevalent United States (U.S.) Group A Streptococcus (G... | 08/05/2008 |
| 7324007 | Instrumented rock bolt, data logger and user interface system A rock bolt includes a hollow body and a gap along a length of the hollow body. At least one strain gauge is affixed to an inner surface of the rock bolt and is accessible from the gap. The rock bolt may include a data logger within the hollow body and coupled to re... | 01/29/2008 |
| 7225807 | Systems and methods for aerosol delivery of agents Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is loc... | 06/05/2007 |
| 7223836 | Peptides for chlamydophila pneumoniae vaccine and diagnosis Peptides are disclosed that include SEQ ID NO:1, SEQ ID NO: 2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, and SEQ ID NO:6, or a conservative variant or mimic thereof, wherein the conservative variant or mimic specifically binds an antibody that specifically binds SEQ ID... | 05/29/2007 |
| 7220852 | Coronavirus isolated from humans Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, a... | 05/22/2007 |
| 7209796 | Auscultatory training system According to a disclosed embodiment, an auscultatory training apparatus includes a database of pre-recorded physiological sounds stored on a computer for playing on a playback system. A user-friendly, graphical user interface software program is stored on the comput... | 04/24/2007 |
