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Patent No. 6049912

Mountable Printable Placard With Headband

A resilient headband in a shape for being mounted on the head of the user. The headband is equipped with a longitudinal slotted member for holding a placard.

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Assignee: The Trustees of the University of Pennsylvania


Location: Philadelphia, PA
No. of patents: 697

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NumberTitleIssue Date
8183352Attenuated vif DNA immunization cassettes for genetic vaccines
The present invention is directed to nucleic acid molecules encoding attenuated, non-functional virion infectivity factor (vif) proteins. The nucleic acid molecules of the invention are inserted into recombinant expression vectors and administered to mammals in orde...
05/22/2012
8173786Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same
Fusion proteins and nucleic acid molecules encoding fusion proteins are disclosed. Fusion proteins comprising non-IL-15 signal peptide linked to IL-15 protein sequences and fusion proteins comprising an IgE signal peptide linked to non-IgE protein sequences are disc...
05/08/2012
8173335Beam ablation lithography
Provided are beam ablation lithography methods capable of removing and manipulating material at the nanoscale. Also provided are nanoscale devices, nanogap field effect transistors, nano-wires, nano-crystals and artificial atoms made using the disclosed methods....
05/08/2012
8168769HPV vaccines and methods for using the same
Improved anti-HIV immunogens and nucleic acid molecules that encode them are disclosed, Immunogens disclosed include those having consensus sequences for HIV Subtype A Envelope protein, those having consensus sequences for HIV Subtype B Envelope protein, those havin...
05/01/2012
8158119Cardiac targeted delivery of cells
A method of delivering cardiac stem cell and treating damaged cardiac tissue is provided. The method involves isolation of subject's cardiac circulation from the subject's systemic circulation and perfusing a solution comprising stem cells into the cardiac circuit.
04/17/2012
8150522Active control of epileptic seizures and diagnosis based on critical systems-like behavior
Developing a measure of critical systems-like behavior in an epilepsy patient in order to map epileptic networks, either passively or evoking responses through subthreshold stimulation, and to apply “therapeutic” stimulations to the patient that cause smaller, b...
04/03/2012
8148982Spin locked balanced steady-state free precession (slSSFP) with off-resonance spin locked pulses interleaved with imaging gradients
A spin locked balanced steady-state free precession (slSSFP) pulse sequence combines a balanced gradient echo acquisition with an off-resonance spin lock pulse for fast MRI. The transient and steady-state magnetization trajectory is solved numerically using the Bloc...
04/03/2012
8147823Method of treating or retarding the development of blindness
A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by subretinal injection an effective amount of a recombinant adeno-associated viru...
04/03/2012
8145436Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs ...
03/27/2012
8138361C-10 carbamates of taxanes
Provided herein are C-10 taxane carbamates and pharmaceutically acceptable derivatives thereof. In certain embodiments, provided herein are compounds, compositions and methods for treating cancer and taupathy. ...
03/20/2012
8137972Biocompatible, biodegradable polymer-based, lighter than or light as water scaffolds for tissue engineering and methods for preparation and use thereof
Scaffolds for tissue engineering prepared from biocompatible, biodegradable polymer-based, lighter than or light as water microcarriers and designed for cell culturing in vitro in a rotating bioreactor are provided. Methods for preparation and use of these scaffolds...
03/20/2012
8135452Rapid 3-dimensional bilateral breast MR imaging
Provided is a method for rapid, 3D, dynamic, projection reconstruction bilateral breast imaging using simultaneous multi-slab volume excitation and radial acquisition of a contrast enhanced bilateral image, in conjunction with SENSE processing, using k-Space Weighte...
03/13/2012
8133723Vaccines against multiple subtypes of influenza virus
An aspect of the present invention is directed towards DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of influenza virus subtypes, comprising a DNA plasmid and a pharmaceutically acceptable excipient. The DNA plasmid is...
03/13/2012
8133687Labor biomarkers, methods comprising same, and methods targeting same
The present invention provides methods of predicting or detecting labor in a female subject and methods of testing a compound for an ability to delay the onset of labor. The present invention also provides methods of testing a labor marker useful in the diagnostic m...
03/13/2012
8133482Activatable photodynamic therapy agents
The present invention relates to the field of conjugates comprising a substrate which is attached to at least one photoactivatable killing agent and at least one first quencher, and methods for their use. More particularly, the present invention relates to photodyna...
03/13/2012
8129185Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses
Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and culture-expanded isolated CD4+CD25+ suppressor Tr...
03/06/2012
8124742Rh(D)-binding proteins
The invention includes Rh(D) binding proteins, including antibodies, and DNA encoding such proteins. Methods of generating such proteins and DNAs are also included. ...
02/28/2012
8124105Compositions, methods and kits relating to poxvirus subunit vaccines
The invention is directed to a poxvirus vaccine comprising a soluble truncated poxvirus envelope protein. The invention is also directed to a vaccine comprising a nucleic acid encoding such proteins. Also included is an antibody which specifically binds to the prote...
02/28/2012
8119395Vaccines, immunotherapeutics and methods for using the same
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines, recombinant vaccines for delivering foreign antigen and live attenuated vacc...
02/21/2012
8119348Compositions and methods for diagnosing and treating macular degeneration
The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use...
02/21/2012
8118866Method for heart valve implantation
A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to t...
02/21/2012
8117854System and method for producing and determining cooling capacity of two-phase coolants
The invention provides systems and devices for producing two-phase coolants such as an ice slurry. Also provided are methods for producing two-phase coolants, and methods for using the two-phase coolants to lower the temperature or maintain a low temperature in any ...
02/21/2012
8116009Far-field sub-diffraction optical lenses (FaSDOL)
Far-field sub-diffraction optical lenses “FaSDOLs” comprise an anisotropic crystal having special dispersion characteristics such that it supports diffraction free propagation. An image with subwavelength features on the input surface is transferred through a pr...
02/14/2012
8114414Compositions and methods for treatment of cervical cancer
The present invention provides methods of treating, protecting against, and inducing an immune response against cervical cancer, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO...
02/14/2012
8110557Gamma secretase inhibitor for treatment of herpesvirus infection
This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby a...
02/07/2012
8110551Cytolethal distending toxin and use thereof
This invention relates to immunotoxins and their use. Specifically, the invention relates to compositions comprising Cdt toxins or their inhibitors and their use in methods for treating infectious and proliferative diseases. ...
02/07/2012
8106375Resistance-switching memory based on semiconductor composition of perovskite conductor doped perovskite insulator
Resistance-switching oxide films, and devices therewith, are disclosed. Resistance-switching oxide films, according to certain preferred aspects of the present invention, include at least about 75 atomic percent of an insulator oxide matrix having a conducting mater...
01/31/2012
8106039Metal complex phosphatidyl-inositol-3-kinase inhibitors
Provided are novel organometallic compounds that inhibit PI3K lipid kinase and phospho-AKT in human melanoma cells, and also inhibit the migration of melanoma cells. The present invention is also directed to methods for inhibiting cancer cell proliferation, migratio...
01/31/2012
8105574Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided. ...
01/31/2012
8098430Grating structure for directing non-polarized light
A grating structure having a fused silica base includes alternating ridges and grooves. The ridges and grooves form a fused silica to air interface. The ridges and grooves are configured such that the grating has a ratio between the effective refractive index differ...
01/17/2012
8086294Unified probabilistic framework for predicting and detecting seizure onsets in the brain and multitherapeutic device
A method and system for assessing a quality of life index to adjust an implanted device to optimize patient-specific feature signals and treatment therapies. Accumulated energy of intracranial electroencephalogram (IEEG) signals is calculated over multiple data chan...
12/27/2011
8082015Optical measurement of tissue blood flow, hemodynamics and oxygenation
An embodiment of the invention includes a device, system and method for determining the characteristics of deep tissue. The novel method includes measuring blood flow rate and oxygenation characteristics of the tissue, and determining oxygen metabolism of the tissue...
12/20/2011
8080660Metal complex glycogen synthase kinase 3 inhibitors
The present inventive subject matter relates to novel metal complex glycogen synthase kinase 3 inhibitors, methods for making such compounds, and methods for using such compounds for treating diseases and disorders mediated by glycogen synthase kinase 3 activity. Co...
12/20/2011
8076936Reducing imaging-scan times for MRI systems
Provided are methods and systems for rapid MRI imaging-scanning that provides 2D or 3D coverage, high precision, and high-temporal efficiency, without exceeding SAR limits. In one embodiment, a pulse sequence process is performed that includes a T1ρ prep...
12/13/2011
8075921Rapamycin-resistant T cells and therapeutic uses thereof
Methods for generating highly enriched Th1/Tc1 and Th2/Tc2 functions are described. In particular, the generation of these functions are attained by the addition of an immune suppression drug, rapamycin or a rapamycin derivative compound. In addition to enhanced pur...
12/13/2011
8072684Optical device using laterally-shiftable diffraction gratings
A double-sided grating divider acts as a light switch where the upper and lower grating dividers are arranged to accommodate a relative lateral shift therebetween of about one-fourth of the period of the diffraction grating elements and where the critical refraction...
12/06/2011
8071325Flow cytometric method and kit for metal-induced sensitivity
This invention provides methods for determining metal-induced sensitivity of a subject and kits for affecting the same. Specifically, the invention provides methods for using immune cell proliferation resulting from exposure to test metals as a method for determinin...
12/06/2011
8070802Mitral valve system
Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via transcatheter techniques. The valve prosthesis may include a resilient ring, a plural...
12/06/2011
8067557OCL-2A3 compositions and uses thereof
This invention relates to osteoclast-specific genes and proteins. Specifically, the invention relates to OCL-2A3 or Atp6v0d2, the gene encoding it and uses thereof in methods and treatment of bone disorders. ...
11/29/2011
8065015Regulation of genes via application of specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or injured tissue for treatment. By gene expression is meant the up reg...
11/22/2011
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