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Assignee: The Trustees of Dartmouth College


Location: Hanover, NH
No. of patents: 55

1    
NumberTitleIssue Date
8174253Systems and methods that detect changes in incident optical radiation
Systems, methods and sensors detect changes in incident optical radiation. Voltage is applied across one or more active areas of a detector while the incident optical radiation illuminates the active areas. Current is sensed across one or more of the active areas, a...
05/08/2012
8172126Joining of parts via magnetic heating of metal-aluminum powders
A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase nanocrystalline magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF...
05/08/2012
8101024Removal of minerals from cellulosic biomass
Disclosed is a method for removing minerals from a cellulosic biomass. For example, the biomass may be prewashed with an acid solution and rinsed with water to remove minerals prior to acid saccharification. The removal of minerals may reduce overall acid requiremen...
01/24/2012
8067465Tricyclic-bis-enone derivatives and methods of use thereof
Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral s...
11/29/2011
7981058Intelligent wearable monitor systems and methods
An intelligent wearable monitoring system includes a wireless personal area network for extended monitoring of a patient's motor functions. The wireless personal area network includes an intelligent accelerometer unit, a personal server and a remote access unit. The...
07/19/2011
7962198System and method for spectral-encoded high-rate hemodynamic tomography
An optical tomography system has a group of lasers for generating light of multiple distinct wavelengths within a first wavelength band. Light from these lasers is directed into mammalian tissue at laser-specific locations on the tissue, and light from the mammalian...
06/14/2011
7883609Ice modification removal and prevention
An alternating electric field is applied to ice (530) to generate a resistive AC having a frequency greater than 1000 Hz in interfacial ice at interface (554). A first electrode (510) and a second electrode (514) proximate to the interfac...
02/08/2011
7875444Lignin blockers and uses thereof
Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion and allows for th...
01/25/2011
7829843Electronic time-of-flight mass selector
A method of selecting ions includes generating a group of ions, accelerating the group of ions through a flight region towards an electronic mass selector grid, and selectively varying a voltage applied to the electronic mass selector grid, such that only a selected...
11/09/2010
7815850High-strength nanostructured alloys
Biphasic alloys, formed through a spinodal decomposition process, are disclosed. The alloys have improved strength and hardness, over single phase alloys, due to coherency strain between the phases. They are prepared from readily available transition metals, and the...
10/19/2010
7795305CDDO-compounds and combination therapies thereof
CDDO-compounds in combination with other chemotherapeutic agents induce and potentiate cytotoxicity and apoptosis in cancer cell. One class of chemotherapeutic agents include retinoids. Cancer therapies based on these combination therapies are provided. Also provide...
09/14/2010
7713268Thermokeratoplasty systems
The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes two generally tubular electrical conducting elements coaxially disposed relative to one another and separated by an electrically insulating elem...
05/11/2010
7703300Pulse systems and methods for detaching ice
A pulse system for detaching ice includes a power supply for applying a high-power heating pulse to the interface between ice and an object such as a cold plate of an ice making system, an ice-container, a heat-exchanger, a refrigerator surface or an airplane wing. ...
04/27/2010
7701317Low AC resistant foil winding for magnetic coils on gapped cores
A system and method reduces AC losses in a magnetic coil with a magnetic core with one or more gaps. A foil winding is formed with one or more cavities and is positioned about the magnetic core such that the cavities are adjacent to the gaps. ...
04/20/2010
7647642System and method for managing copyrighted electronic media
Copyrighted electronic media are packaged in a secure electronic format, and registered on associated registration server, which serves to provide on-line licensing and copyright management for that media. Users are connected to the server, e.g., through a computer ...
01/12/2010
7638735Pulse electrothermal and heat-storage ice detachment apparatus and methods
Systems and methods for pulse electrothermal and heat-storage ice detachment. A pulse electrothermal ice detachment apparatus includes one or more coolant tubes, and optionally, fins in thermal contact with the coolant tubes. The tubes and/or fins form a resistive h...
12/29/2009
7629558Systems and methods for modifying an ice-to-object interface
A method for controlling a coefficient of friction between an object and ice includes steps of (1) pulsing power to an interface between the object and the ice to melt an interfacial layer of ice at the interface and decrease the coefficient of friction, (2) facilit...
12/08/2009
7604967Lignin-blocking treatment of biomass and uses thereof
Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion. Cellulase effici...
10/20/2009
7503981Removal of minerals from cellulosic biomass
Disclosed is a method for removing minerals from a cellulosic biomass. For example, the biomass may be prewashed with an acid solution and rinsed with water to remove minerals prior to acid saccharification. The removal of minerals may reduce overall acid requiremen...
03/17/2009
7439736Imaging by magnetic resonance adsorption, elastography and tomography
Magnetic resonance elastography pulse sequences for encoding position and motion of spins, and methods of using the pulse sequences are disclosed. The pulse sequences utilize imaging gradients, comprising a positive lobe and a negative lobe having non-symmetric ampl...
10/21/2008
7435755CDDO-compounds and combination therapies thereof
CDDO-compounds in combination with other chemotherapeutic agents induce and potentiate cytotoxicity and apoptosis in cancer cell. One class of chemotherapeutic agents include retinoids. Cancer therapies based on these combination therapies are provided. Also provide...
10/14/2008
7423279Systems and methods that detect changes in incident optical radiation
Systems, methods and sensors detect changes in incident optical radiation. Current is driven through one or more active areas of a detector while the incident optical radiation illuminates the active areas. Voltage is sensed across one or more of the active areas, a...
09/09/2008
7377917Feedback control of thermokeratoplasty treatments
A microwave thermokeratoplasty system uses an applicator having embedded sensors that provide feedback signals to a controller. The controller interprets these feedback signals to dynamically adjust or cease a keratoplasty operation. The system uses a microwave appl...
05/27/2008
7365550Low impedance test fixture for impedance measurements
A test fixture couples with a test instrument to measure impedance of a device. An upper layer of the test fixture has (a) a first and a second solder pad for electrical connection to the device, (b) a first, second, third and fourth multi-solder pad for electrical ...
04/29/2008
7296163System and methods for encrypted execution of computer programs
The invention provides a method for encrypting a program for execution on a remote host computer on a network, such that correct execution by the remote host computer is ensured, and such that the remote host computer remains unaware of the computations or data asso...
11/13/2007
7227110Prevention of ice formation by applying electric power to a liquid water layer
A first electrode is separated from a second electrode by an interelectrode space. The interelectrode space does not exceed 3 mm, and preferably does not exceed 100 μm. Liquid water fills the interelectrode space, thereby electrically connecting the first electrode...
06/05/2007
7192429Thermokeratoplasty systems
The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes two generally tubular electrical conducting elements coaxially disposed relative to one another and separated by an electrically insulating elem...
03/20/2007
7189891Isolated ferric reductase defective polypeptides and uses thereof
Novel molecules of the multi-drug and toxin efflux (MATE) family of molecules, designated herein as mutant ferric reductase defective (FRD3) nucleic acid and protein molecules are disclosed. The FRD3 nucleic acid and protein molecules are useful as modulating agents...
03/13/2007
7176237Tricyclic-bis-enone derivatives and methods of use thereof
Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral s...
02/13/2007
7164100High-frequency de-icing of cableways
High-frequency AC voltage with a frequency in a range of from 60 to 100 kHz supplied from a power source at 3 to 15 kV is applied to an electrical conductor within about 30 cm of a cableway. The high-frequency AC voltage generates an alternating electric field. Capa...
01/16/2007
7138599Plasma-based de-icing
An electrical conductor and a gas-filled layer are located at or near the surface of an object being deiced. The conductor carries an AC voltage that generates an alternating electric field in the gas-filled layer. A conductive layer increases the electric field str...
11/21/2006
7092853Environmental noise monitoring system
A continuous environmental noise level recording and analysis system is provided. The system is capable of sampling, processing and storing Equivalent Sound Level values over a period of about two weeks. The recorded data is downloaded and analyzed to show graphs, a...
08/15/2006
7087876High-frequency melting of interfacial ice
An alternating electric field is applied at an ice interface to generate a resistive AC current having a frequency greater than 1000 Hz in interfacial ice. Typically, a first electrode and a second electrode proximate to the interface are separated by an interelectr...
08/08/2006
7034257Methods for modifying friction between an object and ice or snow
A method modifies friction between an object and ice or snow. The method utilizes a heating element to apply a pulse of thermal energy to an interface between the object and the ice or snow; the first pulse is sufficient to melt an interfacial layer of ice at the in...
04/25/2006
6974801Inhibitors and methods of use thereof
New triterpenoid derivatives with various substituents at the C-17 position of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) were synthesized. Among them, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile (CNDDO), 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-...
12/13/2005
6870139Systems and methods for modifying an ice-to-object interface
Systems and methods for thermally modifying an ice-to-object interface. One system includes a power supply configured to generate a magnitude of power. The magnitude of the power is sufficient to melt an interfacial layer of ice at the interface; typically the inter...
03/22/2005
6832742System and method for an electrical de-icing coating
A system for modifying ice adhesion strength of ice adhered to an object comprises a composite coating containing wire electrodes covering the surface to be protected. In one embodiment, a composite coating contains electrode wires and insulator fibers. The composit...
12/21/2004
6818831Systems and methods for modifying ice adhesion strength
Systems and methods for modifying ice adhesion strength of ice adhered to an object. An electrode is electrically insulated from the object and a power source, e.g., a battery, is coupled to the object and the electrode. The source generates power to an interface be...
11/16/2004
6743172System and method for displaying medical process diagrams
A system and method is described for determining and graphically displaying oxygenation states of a patient in real time. The system is non-invasive and can display information to a physician that is intuitive. Various display objects are described for illustrating ...
06/01/2004
6723971Methods and structures for removing ice from surfaces
In one embodiment, a system for modifying ice adhesion strength of ice adhered to an object. The system includes an electrode that is electrically insulated from the object and a DC source, e.g., a battery coupled to the object and the electrode. The source generate...
04/20/2004
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