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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 8071282 | Method of storing red blood cells with an acidic additive solution under oxygen depletion There is provided compositions and methods for the storage of red blood cells. The compositions are additive solutions comprising adenine, dextrose, mannitol, NaH2PO4, and optionally NaCl and/or NH4Cl. Composition are preferably used... | 12/06/2011 |
| 8035113 | Optical devices featuring textured semiconductor layers A semiconductor sensor, solar cell or emitter, or a precursor therefor, has a substrate and one or more textured semiconductor layers deposited onto the substrate. The textured layers enhance light extraction or absorption. Texturing in the region of multiple quantu... | 10/11/2011 |
| 7999095 | Nucleic acid supported protein complementation The present invention is directed to novel methods for in vitro and in vivo detection of target nucleic acid molecules, including DNA and RNA targets, as well as nucleic acid analogues. The present invention is based on protein complementation, in which two individu... | 08/16/2011 |
| 7910624 | Compositions for the treatment of blood disorders The invention relates to compositions containing chemical compounds and compositions containing steel factor which stimulate the expression of hemoglobin or globin protein such as embryonic or fetal globin, or the proliferation of hemoglobin expressing and other cel... | 03/22/2011 |
| 7777241 | Optical devices featuring textured semiconductor layers A semiconductor sensor, solar cell or emitter or a precursor therefore having a substrate and textured semiconductor layer deposited onto the substrate. The layer can be textured as grown on the substrate or textured by replicating a textured substrate surface. The ... | 08/17/2010 |
| 7723017 | Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation There are provided methods and compositions for the storage of red blood cells. The compositions are metabolic supplements that are preferably added to refrigerated red blood cells suspended in an additive solution. Red blood cells are preferably stored under condit... | 05/25/2010 |
| 7695680 | Resonant cavity biosensor An assay system having a channel bounded by first and second reflective surfaces adapted to accommodate a fluid material therebetween and defining a plurality of regions in an array between those surfaces with each region defining a resonant cavity and adapted to re... | 04/13/2010 |
| 7663157 | Semiconductor device having group III nitride buffer layer and growth layers An epitaxial growth system comprises a housing around an epitaxial growth chamber. A substrate support is located within the growth chamber. A gallium source introduces gallium into the growth chamber and directs the gallium towards the substrate. An activated nitro... | 02/16/2010 |
| 7662554 | Nucleic acid supported protein complementation The present invention is directed to novel methods for in vitro and in vivo detection of target nucleic acid molecules, including DNA and RNA targets, as well as nucleic acid analogues. The present invention is based on protein complementation, in which two individu... | 02/16/2010 |
| 7649632 | Characterization of micro- and nano scale materials by acoustic wave generation with a CW modulated laser Apparatus for analyzing thin surface layers. An acoustic wave generating laser beam is amplitude modulated with continuous wave modulation of a frequency in the megahertz to gigahertz range and an optical system directs the modulated radiation to a surface of a thin... | 01/19/2010 |
| 7517453 | Microvascular network device A microvascular network device comprising: a substrate; at least one microchannel; at least one opening to the microchannel for sample entry; at least one opening to the microchannel for sample exit; and an aspirator which causes the sample to traverse the microchan... | 04/14/2009 |
| 7501303 | Reflective layer buried in silicon and method of fabrication A silicon wafer having a distributed Bragg reflector buried within it. The buried reflector provides a high efficiency, readily and accurately manufactured reflector with a body of silicon. A photodetector using the buried layer to form a resonant cavity enhancement... | 03/10/2009 |
| 7485427 | Photocleavable bioreactive agents This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a... | 02/03/2009 |
| 7485385 | Process for solid oxide fuel cell manufacture The present invention provides a method for conveniently manufacturing a solid oxide fuel cell (SOFC) at a cost that is less than five-hundred dollars per kilowatt of electricity. The method comprises forming an electrode layer and depositing an electrolyte material... | 02/03/2009 |
| 7435562 | Modular vector systems The present invention provides improved techniques and reagents for producing nucleic acid molecules. In certain preferred embodiments, the nucleic acid molecules are modular vectors. In certain preferred embodiments, the nucleic acid molecules are produced in polym... | 10/14/2008 |
| 7393384 | Hydrogen separation using oxygen ion-electron mixed conduction membranes A process for purification of hydrogen from a stream of synthesis gas or other reformate gases is described. The process, generally conducted at temperatures of approximately 800-1000° C., involves the use of a cell in which a mixture of reformate gas and steam are... | 07/01/2008 |
| 7339045 | Bioreactive agents This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a... | 03/04/2008 |
| 7336187 | Patient activity monitor A patient activity monitoring system that allows caregivers of multiple patients to work more efficiently and with reduced cost, while increasing the quality and level of patient care. The system includes a plurality of remote monitoring subsystems, a plurality of u... | 02/26/2008 |
| 7319003 | Arrays of probes for positional sequencing by hybridization This invention is directed to methods and reagents useful for sequencing nucleic acid targets utilizing sequencing by hybridization technology comprising probes, arrays of probes and methods whereby sequence information is obtained rapidly and efficiently in discret... | 01/15/2008 |
| 7312038 | Photocleavable bioreactive agents This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a... | 12/25/2007 |
| 7309606 | Methods and compositions for treating hypercholesterolemia The present invention provides methods and compositions for treating hypercholesterolemia using therapeutic apoE proteins. A therapeutic apoE protein is a naturally-occurring apoE protein (e.g., apoE1, apoE2, apoE2*, apoE2**, apoE3, and apoE4) that has one or more a... | 12/18/2007 |
| 7251609 | Method for conducting clinical trials over the internet The invention encompasses a method of conducting a clinical trial of a test substance from a primary site, via the internet. The internet is used in various phases of a clinical trial, including: recruiting and screening for candidates who are eligible to participat... | 07/31/2007 |
| 7235819 | Semiconductor device having group III nitride buffer layer and growth layers An epitaxial growth system comprises a housing around an epitaxial growth chamber. A substrate support is located within the growth chamber. A gallium source introduces gallium into the growth chamber and directs the gallium towards the substrate. An activated nitro... | 06/26/2007 |
| 7230415 | Quantum junction device as switch and detector A quantum junction device having three or more wires connected to a loop surrounding a magnetic flux is used to act as a switch responsive to magnetic flux and therefore useable for mass storage devices or as a flux detector by sensing current direction, conductance... | 06/12/2007 |
| 7211394 | Detection of markers in nascent proteins The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 05/01/2007 |
| 7208120 | Cellular diagnostic arrays, methods of using and processing for producing same A cellular diagnostic array has been developed that provides accurate and reproducible measurements of the physical parameters of individual cells en masse, including cell membrane surface area, cell volume, and excess membrane. Three differing patterns are employed... | 04/24/2007 |
| 7202949 | Binocular spectrometer A direct-view handheld binocular spectrometer for use in a variety of educational settings. The device comprises a holographic transmission diffraction grating and a uniquely curved quantitative wavelength scale for viewing visible-wavelength spectra with both eyes ... | 04/10/2007 |
| 7195874 | Detecting targets in heterologous mixtures This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a... | 03/27/2007 |
| 7169558 | Detection of disease related genes The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 01/30/2007 |
| 7098718 | Tunable current-mode integrator for low-frequency filters A tunable current mode integrator for low-frequency continuous-time filters that requires a reduced amount of area when implemented in an integrated circuit (IC). The integrator includes input and output transistors, and cross-coupled current mirrors, integration ca... | 08/29/2006 |
| 7038041 | Selective nuclear receptor-targeted systems for delivery of cytotoxins to cancer cells for targeted photodynamic therapy An estrogen/antiestrogen-porphyrin conjugate, their composition and methods for their use are claimed. The active compounds of the invention are conjugates consisting of an estrogen or anti estrogen portion, tether or linker portion and a porphyrin portion. The meth... | 05/02/2006 |
| 6991903 | Solid phase sequencing of double-stranded nucleic acids Methods for detecting and sequencing of target double-stranded nucleic acid molecules, nucleic acid probes and arrays of probes useful in these methods, and kits and systems that contain these probes are provided. The methods involve hybridizing the nucleic acids or... | 01/31/2006 |
| 6953703 | Method of making a semiconductor device with exposure of sapphire substrate to activated nitrogen An epitaxial growth system comprises a housing around an epitaxial growth chamber. A substrate support is located within the growth chamber. A gallium source introduces gallium into the growth chamber and directs the gallium towards the substrate. An activated nitro... | 10/11/2005 |
| 6949341 | Diagnosing genetic disorders This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a... | 09/27/2005 |
| 6929721 | Ion beam modification of residual stress gradients in thin film polycrystalline silicon membranes Method and apparatus for reducing the curvature of a micromachined structure having lamella (12). Surface treatment by an ion beam (30) of the lamella (12) such as by sputtering removes regions of stress allowing the lamella (12) to retur... | 08/16/2005 |
| 6919179 | Detection of markers in nascent proteins The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 07/19/2005 |
| 6907881 | Variable peak pressure ventilation method and system A system and method for ventilating a lung in a living being by varying the peak inspiratory pressure. The peak inspiratory pressure may deviate about a mean that is chosen to correspond with a knee in a pressure-volume curve of the lung. ... | 06/21/2005 |
| 6887853 | Use of geldanamycin and related compounds for treatment of fibrogenic disorders A method for prophylaxis or treatment of a mammal, particularly human, at risk for a fibrogenic disorder is disclosed. The compositions and methods of the invention are directed both to treatments for existing fibrogenic disorders and prevention thereof. Such disord... | 05/03/2005 |
| 6840117 | Patient monitoring system employing array of force sensors on a bedsheet or similar substrate A patient monitoring system includes a replaceable laminar sensor to be placed on a bed, the sensor including distributed force sensing elements providing output signals to processing apparatus including a near-bed processor and a central processor coupled to the ne... | 01/11/2005 |
| 6705345 | Micro valve arrays for fluid flow control An array of micro valves, and the process for its formation, used for control of a fluid flow and having a substrate with a plurality of apertures for directing the fluid to flow from one side to another. A micromechanically formed fluid seal surrounds each aperture... | 03/16/2004 |
