...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 6689940 | Nucleic acid encoding the arabidopsis ELF3 protein and a method of using it to alter photoperiod in plants The nucleic acid that encodes the Arabidopsis ELF3 protein, which is involved in photoperiodism and circadian rhythms, is disclosed. This nucleic acid may be introduced into plants in order to alter the photoperiodic and/or circadian clock-based gene expr... | 02/10/2004 |
| 6556978 | Satisfiability algorithms and finite quantification Subsearch, where a satisfiability algorithm searches through the original theory for ground clauses that satisfy some numeric property, is represented in terms of S(C,P,u,s), the set of ground instances of C that have u literals unvalued by P and s litera... | 04/29/2003 |
| 6433251 | Promoter regulating circadian clock function and photoperiodism Nucleic acid molecules that encode a plant promoter involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic and/or circadian clock-based gene expression of the plant... | 08/13/2002 |
| 6272483 | Cost-optimizing allocation system and method A system for determining schedules and processing other optimization problems includes a local optimization engine and a global optimization engine. The local optimization engine operates based on heuristics, and includes a prioritizer, a constructor, and... | 08/07/2001 |
| 6150176 | Fluorescent protein sensors for measuring the pH of a biological sample Disclosed are fluorescent protein sensors for measuring the pH of a sample, nucleic acids encoding them, and methods of use. The preferred fluorescent protein sensors are variants of the green fluorescent protein (GFP) from Aequorea victoria. Also disclos... | 11/21/2000 |
| 5830539 | Methods for functionalizing and coating substrates and devices made according to the methods Methods for coating substrates are described. The methods comprise coating at least a portion of a substrate with particular coating materials. The coating materials can be crosslinked and coated onto a substrate. Alternatively, the coating materials may ... | 11/03/1998 |
| 5825725 | Method and apparatus for reversible optical data storage Storage, retrieval and erasure of optical information in bacteriorhodopsin (bR) films by alteration of the bR's absorption spectrum by photo-induction and by application and switching of an electrical field.... | 10/20/1998 |
| 5545394 | Complexation-mediated crystal-forming reactions using complexing agents Methods and reaction systems are disclosed that are adapted for forming crystallites having novel crystal habits and/or morphologies compared to conventional crystallites of the same chemical composition. The methods and reaction systems involve chemical ... | 08/13/1996 |
| 5514680 | Glycine receptor antagonists and the use thereof Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and D... | 05/07/1996 |
| 5340983 | Method and apparatus for mass analysis using slow monochromatic electrons Methods and apparatuses are disclosed for mass-analysis of a sample for particular analytes of interest. An electron monochromator is coupled to any of a number of different types of mass analyzer and used to generate slow electrons used to produce ions o... | 08/23/1994 |
| 5322799 | Observation cell and mixing chamber A device for detecting substances in a liquid film by measuring chemiluminescence, fluorescence or absorption using techniques such as flow-injection analysis schemes, liquid chromatographies, and gas chromatographies. The device can be used as a micro-vo... | 06/21/1994 |
| 5304492 | Spectrophotometer for chemical analyses of fluids An apparatus that conducts in situ analyses of fluids in real time is disclosed. The apparatus comprises bifurcated optic fibers, a pulsed light source, a light detector, a water-tight pressure case that houses the pulsed light source and the light detect... | 04/19/1994 |
| 5260061 | Propionibacteria metabolites inhibit spoilage yeast in foods A metabolite material of propionibacteria is added to a food product to inhibit the growth of yeast. The metabolite material is produced by growing propionibacteria cells in a liquid growth medium to produce a mixture containing the metabolite material. T... | 11/09/1993 |
| 5252317 | Amplifier molecules for diagnosis and therapy derived from 3,5-bis[1-(3-amino-2,2-bis (aminomethyl)-propyl) oxymethyl] benzoic acid Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each com... | 10/12/1993 |
| 5239251 | Brushless doubly-fed motor control system An AC variable speed drive (VSD) system having a brushless doubly-fed motor receives power from an electric power grid at a system frequency of the grid and drives a mechanical load. The motor has a rotor with rotor windings and a stator with stator windi... | 08/24/1993 |
| 5200508 | Cell surface antigen that binds with L6 monoclonal antibody We disclose the discovery and purification of a tumor antigen that binds the mouse monoclonal antibody L6. Immunohistochemical analysis showed that the antigen is expressed on the membrane surface of LX-1 human lung tumor cells, which retain L6 binding ac... | 04/06/1993 |
| 5176028 | Device for testing adhesive bonds An adhesive is applied to overlapping portions of a two-part test sample located between opposing press heads of the bond testing device. The press heads then press together the overlapping portions for a specific period of time while heating the test sam... | 01/05/1993 |
| 5135737 | Amplifier molecules for enhancement of diagnosis and therapy Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each com... | 08/04/1992 |
| 5107530 | X-ray diffractometer with shutter control A reliable shutter position indicator for an x-ray diffractometer utilizes an optical shutter position sensor for detecting the position of a shutter of the x-ray diffractometer. In one embodiment, a pair of optical isolators are utilized with an arm coup... | 04/21/1992 |
| 5096718 | Preserving foods using metabolites of propionibacteria other than propionic acid A metabolite material of propionibacteria, having a metabolite of molecular weight greater than 300, is added to a food product to inhibit the growth of gram negative psychotropic bacteria, yeast, mold, gram positive bacteria, or Listeria. The metabolite ... | 03/17/1992 |
| 5083077 | Brushless doubly-fed generation system for vehicles An onboard power generation system for use on board a vehicle, such as a passenger car, includes a brushless doubly-fed generator. The generator has a rotor with rotor conductors and a stator with stator windings, the stator windings comprising first and ... | 01/21/1992 |
| 5059415 | Method for diagnostically imaging lesions in the brain inside a blood-brain barrier An improved method for diagnosing and characterizing brain lesions is described which first involves chemically modifying the blood-brain barrier (BBB) in order to increase BBB permeability. Thereafter, a chemical agent (e.g. monoclonal antibody) is intro... | 10/22/1991 |
| 5028804 | Brushless doubly-fed generator control system An energy conversion generation system receives energy from a resource and converts the energy into electrical power for supply to a polyphase electric power grid operating at a system frequency. A prime mover driven by the resource energy and a converter... | 07/02/1991 |
| 5026837 | DNA probe which reveals a hypervariable region on human chromosome 16 A DNA probe p79-2-23 is homologous to at least a portion of a hypervariable DNA region located on chromosome 16q22.fwdarw.q24 in the human genome. The DNA region displays a restriction fragment length polymorphism when digested with certain restriction en... | 06/25/1991 |
| 4994684 | Doubly fed generator variable speed generation control system Disclosed is a device and method to control the conversion of an arbitrary resource energy into mechanical energy and subsequently into electric energy with a variable-speed generation system utilizing a turbine and a doubly-fed generator, to be connected... | 02/19/1991 |
| 4983406 | Preservation of feed This invention relates to the preservation of high moisture animal feeds which utilize a fermentation (either natural or induced) to improve the quality of the animal food. More specifically, this invention utilizes dimethyl fumarate (DMF) in plant feeds ... | 01/08/1991 |
| 4980461 | DNA probe which reveals a hypervariable region on human chromosome 2 A DNA probe which is homologous to at least a portion of a hypervariable DNA region D2S3 located at chromosome 2q35-37 in the human genome. The DNA region displays restriction fragment length polymorphism when digested with certain restriction endonucleas... | 12/25/1990 |
| 4968137 | Devices and procedures for in vitro testing of pulse oximetry monitors A device and method for calibration of pulse oximeters is disclosed. A standard specimen that has optical characteristics of hemoglobin of a known oxygen saturation is placed in the light path of a pulse oximeter probe. The image of a pulse is created by ... | 11/06/1990 |
| 4834532 | Devices and procedures for in vitro calibration of pulse oximetry monitors A device and method for calibration of pulse oximeters is disclosed. A standard specimen that has optical charactertistics of hemoglobin of a known oxygen saturation is placed in the light path of a pulse oximeter probe. The image of a pulse is also creat... | 05/30/1989 |
| 4800353 | Micropole undulator Micropole undulators for use in the generation of x-rays from moving charged particles and methods for manufacturing such undulators are disclosed. One type of micropole undulator has two jaws containing rows of spaced apart poles arranged so that each po... | 01/24/1989 |
| 4766076 | Method and buffered bulk starter media for propagation of useful bacteria The invention comprises a novel starter medium for the commercial propagation of acid producing bacteria, such as those used in food fermentation processes. The compositions are unique in that they contain a highly effective buffering ingredient which is ... | 08/23/1988 |
| 4743382 | Method and apparatus for separating suspended solids from liquids Liquid which has been partially clarified in the settling zone of a clarifier tank is channelled through a filtration compartment containing a buoyant particulate filtration media. The media particles are periodically agitated so that trapped solids are s... | 05/10/1988 |
| 4541269 | Gas chromatograph detector A gas chromatographic detector for detection of compounds which fluoresce as a photo-response to light. The detector utilizes a remotely located light source for fluorescent excitation of a compound in a gas phase, and includes apparatus for the measureme... | 09/17/1985 |