Assignee: The Regents of the University of Colorado

Location: Boulder, CO
No. of patents: 126

Number	Title	Issue Date
8062643	Use of neurotoxin therapy for treatment of urologic and related disorders The present invention related to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. ...	11/22/2011
7998040	Force assistance device for walking rehabilitation therapy A physical therapy apparatus for use in conjunction with a treadmill provides an assistive force to a forward movement of the legs. A force assistance device is adapted to attach to the feet or legs of a patient positioned on a motorized treadmill to assist in walki...	08/16/2011
7948468	Systems and methods for driving multiple solid-state light sources The present disclosure may relate generally to controlling multiple light sources and to systems and methods for reducing inefficiencies and interference in a light emitting diode (LED)-based backlighting systems for LCD televisions. ...	05/24/2011
7855281	Cleavable thiocarbonate linkers for polynucleotide synthesis In various embodiments of the invention, novel compositions having a polynucleotide bound to a substrate via a cleavable linker are provided, and methods of cleaving a polynucleotide from a substrate are provided. ...	12/21/2010
7750121	Antibody to telomerase reverse transcriptive The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	07/06/2010
7718047	Electrochemical high pressure pump The invention provides electrochemically-based methods and devices for producing fluid flow and/or changes in fluid pressure. In the methods and devices of the invention, current is passed through a divided electrochemical cell. Adjacent compartments of the cell are...	05/18/2010
7689260	Shape-memory polymer coated electrodes There is provided a slowly implantable electrode. A coating for an electrode, the coating includes a shape-memory polymer. A method for inserting an electrode into brain tissue by inserting an implantable electrode having a shape-memory polymer coated electrode into...	03/30/2010
7682521	Aligned liquid crystal thin films and glasses The present disclosure includes a method that allows one to obtain high quality alignment of nematic or smectic liquid crystal (LC) polymer glasses in thin films. The present disclosure also includes thin films of aligned smectic or nematic LC main-chain polymer gla...	03/23/2010
7679830	Optical systems utilizing multiple phase filters to increase misfocus tolerance An optical imaging system includes optics for imaging a wavefront of electromagnetic radiation to form an image at a detector. The system also includes a plurality of optical phase filters. Each of the phase filters alters phase of the wavefront. The phase filters c...	03/16/2010
7623685	Biometric signatures and identification through the use of projective invariants Techniques, systems and methods for obtaining biometric signatures and identification are described. Broadly stated, embodiments of the present invention utilize specified geometric principles to provide means for accurate biometric identification using projective i...	11/24/2009
7622549	Human telomerase reverse transcriptase polypeptides The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	11/24/2009
7595686	Digital controller for high-frequency switching power supplies A voltage controller (150), the controller comprising: a voltage comparator (700) operative to provide a digital error signal (152); a compensator (300) operative to determine a digital control signal (154) based on said provided e...	09/29/2009
7585622	Increasing the proliferative capacity of cells using telomerase reverse transcriptase The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	09/08/2009
7583167	High frequency magnetic thin film filter A layered microstrip device is described, in which at least two layers of different high internal field/high resonance frequency materials serve as the active elements of the device. The device is designed to filter ranges of high frequency electromagnetic waves, an...	09/01/2009
7560437	Nucleic acid compositions for eliciting an immune response against telomerase reverse transcriptase The present invention is directed to pharmaceutical compositions comprising a telomerase reverse transcriptase polypeptide or a polypeptide homologous to a telomerase reverse transcriptase. The present invention is also directed to pharmaceutical compositions compri...	07/14/2009
7521003	Functionalized nanostructured lyotropic liquid crystal polymers The invention provides cross-linked lyotropic liquid crystal (LLC) copolymers having ordered nanometer-sized pores lined with functional groups. The copolymers are formed by copolymerizing LLC monomers with strong LLC character and functionalized monomers with no or...	04/21/2009
7517971	Muteins of human telomerase reverse transcriptase lacking telomerase catalytic activity The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	04/14/2009
7498394	(Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained The present invention provides novel (meth)acrylic and (meth)acrylamide monomers and polymers produced from those monomers. The monomers of the invention each include only a single vinyl functionality and at least one non-vinyl functionality that can be varied to ac...	03/03/2009
7482331	Diagnosis and treatment of myocardial failure The invention provides a method of treating myocardial failure in a human. The method comprises administering an effective amount of transgene encoding α-MHC that directly causes an increase in the quantity of α-MHC in the myocardial tissue of the heart. ...	01/27/2009
7479772	Active current sharing multiphase DC-DC converter A converter module for use as a phase in a multiphase DC-DC converter having a data bus for transferring current-sharing information is provided. The converter module includes a power stage and a controller. The power stage comprises an input for receiving an input ...	01/20/2009
7456620	Determining dead times in switched-mode DC-DC converters Systems, methods, and apparatuses are disclosed for determining dead-times in switched-mode DC-DC converters with synchronous rectifiers or other complementary switching devices. In one embodiment, for example, a controller for a DC-DC converter determines dead-time...	11/25/2008
7429387	Use of botulinum toxin therapy for treatment of recalcitrant voiding dysfunction The present invention related to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. ...	09/30/2008
7413864	Treating cancer using a telomerase vaccine The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	08/19/2008
7388276	Metal-insulator varactor devices A varactor is configured with first and second conducting layers, spaced apart from one another such that a given voltage can be applied across the first and second conducting layers. Further, an insulator arrangement includes at least one insulator layer disposed b...	06/17/2008
7374948	Methods and apparatus for detection of molecular chirality The disclosure provides methods for the determination of the enantiomeric excess of chiral compounds. The methods involve doping a chiral analyte into an achiral liquid crystal host to form a chiral dopant/host liquid crystal mixture. An electro-optic signature of t...	05/20/2008
7340938	MIS-based sensors with hydrogen selectivity The invention provides hydrogen selective metal-insulator-semiconductor sensors which include a layer of hydrogen selective material. The hydrogen selective material can be polyimide layer having a thickness between 200 and 800 nm. Suitable polyimide materials inclu...	03/11/2008
7341836	Modified cyclic nucleotide gated ion channels The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments,...	03/11/2008
7332111	Devices and methods for the production of particles The present invention provides methods and devices for producing particles with an average diameter less than about 15 μm using the precipitation with compressed fluid-antisolvent (PCA) process and the carbon-dioxide assisted nebulization with a bubble dryer (CAN-B...	02/19/2008
7316727	High-selectivity supported SAPO membranes SAPO membranes and methods for their preparation and use are described. The SAPO membranes are prepared by contacting at least one surface of a porous membrane support with an aged synthesis gel. A layer of SAPO crystals is formed on at least one surface of the supp...	01/08/2008
7297488	Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase This disclosure provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for cancer, and methods of treating telomerase-related conditions, including cance...	11/20/2007
7291699	Product and methods for diagnosis and therapy for cardiac and skeletal muscle disorders Disclosed are products and methods to promote myoblast activation and cardiac and skeletal muscle growth or regeneration, and to treat heart and skeletal muscle diseases, based on the identification of cellular processes affected by prelamin A processing. ...	11/06/2007
7285639	Antibody to telomerase reverse transcriptase The present invention is directed to monoclonal or recombinant antibodies or fragments thereof that bind to human telomerase reverse transcriptase (hTRT) protein. The present invention is also directed to methods of identifying or detecting hTRT polypeptides in biol...	10/23/2007
7262288	Nucleic acids encoding human telomerase reverse transcriptase and related homologs The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of hu...	08/28/2007
7242520	Method for optimizing output in ultrashort-pulse multipass laser amplifiers with selective use of a spectral filter A method for optimizing multipass laser amplifier output utilizes a spectral filter in early passes but not in later passes. The pulses shift position slightly for each pass through the amplifier, and the filter is placed such that early passes intersect the filter ...	07/10/2007
7218448	Extended depth of field optical systems A system for increasing the depth of field and decreasing the wavelength sensitivity of an incoherent optical system incorporates a special purpose optical mask into the incoherent system. The optical mask has been designed to cause the optical transfer function to ...	05/15/2007
7212723	Monolithic waveguide arrays A waveguide array is fabricated by providing a photoreactive material and generating an optical intensity pattern corresponding to a geometry of the waveguide array. A relative translation of the photoreactive material is effected through the optical intensity patte...	05/01/2007
7195911	Mammalian cells that have increased proliferative capacity The present invention is directed to cells comprising a recombinant polynucleotide sequence that encodes a telomerase reverse transcriptase protein, variant, or fragment having telomerase catalytic activity when complexed with a telomerase RNA. ...	03/27/2007
7177515	Surface plasmon devices A device including an input port configured to receive an input signal is described. The device also includes an output port and a structure, which structure includes a tunneling junction connected with the input port and the output port. The tunneling junction is c...	02/13/2007
7166463	Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels The present invention provides modified cyclic nucleotide gated (CNG) channels. In particularly preferred embodiments, the modified CNG channels exhibit increased sensitivity and specificity for cAMP, as compared to wild-type CNG channels. In additional embodiments,...	01/23/2007
7153514	Use of botulinum toxin therapy for prostatic hyperplasia and related disorders The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. ...	12/26/2006

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Assignee: The Regents of the University of Colorado