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| Number | Title | Issue Date |
| 8181544 | Liquid sample evaporator for vapor analysis Preparation methods for introducing liquid samples to gas analysis instruments include 1) complete evaporation of a liquid sample in a sample chamber, and 2) allowing the sample vapor in the sample chamber to equilibrate for a predetermined time. An inert carrier ga... | 05/22/2012 |
| 8170644 | Method for fast multi-slice mapping of myelin water fraction Mapping of myelin water content in white matter may provide important information for early diagnosis of multiple sclerosis and the detection of white matter abnormality in other diseases. It is disclosed here that free induction decay (FID) of each voxel at multipl... | 05/01/2012 |
| 8168415 | Axl fusion proteins as Axl tyrosine kinase inhibitors Disclosed are novel inhibitors of the Axl receptor tyrosine kinase (RTK) and methods of using such inhibitors in a variety of therapeutic approaches in the areas of cancer therapy and anti-thrombosis (anti-clotting) therapy. ... | 05/01/2012 |
| 8153136 | Yeast-based vaccines as immunotherapy Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically... | 04/10/2012 |
| 8137672 | Immunostimulatory regimen comprising administering type 1 interferon and agonistic anti-CD40 antibody A synergistic adjuvant is provided comprising synergistically effective amounts of at least one type 1 interferon and at least one CD40 agonist, wherein these moieties may be in the same or separate compositions. In addition, fusion proteins and DNA conjugates which... | 03/20/2012 |
| 8112594 | Efficient point-to-point enqueue and dequeue communications Systems and methods for writing and/or reading data to a point-to-point shared memory communication mechanism are provided according to embodiments disclosed herein. According to one embodiment, a determination may be made whether a first memory location in the cach... | 02/07/2012 |
| 8076304 | Methods and compositions for the diagnosis and treatment of cyclin A-1 associated conditions The present invention relates to compositions and methods for cancer therapeutics. In particular, the present invention provides compositions and methods for inhibiting cancer metastasis by inhibiting cyclin A1. ... | 12/13/2011 |
| 8071645 | Systems and methods for treating human inflammatory and proliferative diseases and wounds, with fatty acid metabolism inhibitors and/or glycolytic inhibitors Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a fatty acid metabolism inhibitor, a glycolytic inhibitor, and/or an agent able to alter cellular production of reactive oxygen, or combination thereof, option... | 12/06/2011 |
| 8007804 | Complement receptor 2 targeted complement modulators Modulation of the complement system represents a therapeutic modality for numerous pathologic conditions associated with complement activation. In a strategy to prepare complement inhibitors that are targeted to sites of complement activation and disease, compositio... | 08/30/2011 |
| 7956592 | Monitoring and control of power converters A digital controller configured to inject a signal into a digital feedback path that facilitates regulation of a power converter and measure the corresponding phase, gain, or frequency. The digital controller may also include an adaptive tuning controller for adjust... | 06/07/2011 |
| 7943680 | Stress relaxation in crosslinked polymers The invention provides methods for inducing reversible chain cleavage of polymer chains in a crosslinked polymeric material. Reversible cleavage of the polymer backbone is capable of relieving stress in the polymeric material as the bonds reform in a less stressed s... | 05/17/2011 |
| 7931824 | Surfactants and polymerizable surfactants based on room-temperature ionic liquids that form lyotropic liquid crystal phases with water and room-temperature ionic liquids A modular surfactant architecture based on room temperature ionic liquids (RTILs) has been developed that affords non-polymerizable and polymerizable amphiphiles that form lamellar (L), hexagonal (H) or bicontinuous cubic (Q) LLC phases when mixed with water or RTIL... | 04/26/2011 |
| 7915285 | Method for treating drug and behavioral addictions The present invention is directed to the use of ibudilast for treating addictions, including drug and behavioral addictions. In particular, ibudilast is used to diminish the dopamine-mediated reward associated with addictions and to treat withdrawal syndromes after ... | 03/29/2011 |
| 7914714 | Methods and apparatus using electrostatic atomization to form liquid vesicles The methods of the invention employ electrostatic atomization to form a compound droplet of at least two miscible fluids. The compound droplet comprises a core of a first fluid and a layer of a second fluid completely surrounding the core. The first fluid contains t... | 03/29/2011 |
| 7902803 | Digital current mode controller A digital current-mode controller for a DC-DC converter is disclosed. The controller comprises a digital current reference; and a current loop compensator adapted to receive a digital current error signal derived from a digital current sample sensed from the DC-DC c... | 03/08/2011 |
| 7846688 | Broad host range vectors for shotgun and expression library cloning in Gram negative bacteria The present invention concerns methods and compositions for the construction of a series of stable vectors for genomic library construction useful in Gram negative species. In certain embodiments, the vectors contain the pBBR1 replicon, capable of to stable replicat... | 12/07/2010 |
| 7858349 | Anti-cancer compounds The invention provides bradykinin antagonists and pharmaceutically acceptable salts thereof having anti-cancer activity. These anti-cancer compounds are particularly useful for inhibiting the growth of lung and prostate cancers. ... | 12/28/2010 |
| 7850970 | Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), mycobacterium... | 12/14/2010 |
| 7842485 | Enhanced alcohol tolerant microorganism and methods of use thereof Embodiments of the present invention provide methods and compositions for microorganisms having increased alcohol tolerance. In certain embodiments, methods for using such microorganisms, and methods for identifying gene or genetic regions responsible for increased ... | 11/30/2010 |
| 7838571 | Photopolymers and use in dental restorative materials Photopolymerizable polymer composites based on dimethacrylate systems have been increasingly utilized as dental restorative materials. One of the biggest drawbacks of current dental resin systems is the volume shrinkage and shrinkage induced stresses that arise duri... | 11/23/2010 |
| 7828875 | Membranes for highly selective separations The present invention provides modified molecular sieve membranes with improved CO2/CH4 separation selectivity and methods for making such membranes. The molecular sieve membranes are modified by adsorption of a modifying agent, such as ammonia... | 11/09/2010 |
| 7807781 | Inhibitors of serine protease activity and their use in methods and compositions for treatment of viral infections A novel method of treating and preventing viral infection is provided. In particular a method of blocking viral infection facilitated by a serine proteolytic (SP) activity is disclosed, which consists of administering to a subject suffering or about to suffer from v... | 10/05/2010 |
| 7764023 | Capacitive coupling to aid ignition in discharge lamps A method and apparatus for aiding ignition in a discharge lamp is provided. In one embodiment, a method comprises: applying a voltage across a pair of electrodes of a discharge lamp and capacitively coupling the discharge lamp. The capacitive coupling of the dischar... | 07/27/2010 |
| 7763259 | Therapeutic and prophylactic vaccine for the treatment and prevention of papillomavirus infection This invention provides compositions including a chimera of papillomavirus capsid polypeptide L2 and polypeptide including an immunotherapeutic epitope, and GST fusions thereof. The present invention also provides complexes comprising chimeras of papillomavirus L2 p... | 07/27/2010 |
| 7760342 | Multidimensional spectrometer A multidimensional spectrometer for the infrared, visible, and ultraviolet regions of the electromagnetic spectrum, and a method for making multidimensional spectroscopic measurements in the infrared, visible, and ultraviolet regions of the electromagnetic spectrum.... | 07/20/2010 |
| 7749490 | Mutant IL-10 IL-10 sequence variants are disclosed that retain the therapeutically desirable anti-inflammatory properties of wild-type IL-10 but do not retain the hemoatopoeitic cell regulatory and cell proliferative activities. The mutant IL-10 polypeptides of the invention are... | 07/06/2010 |
| 7732750 | Wavefront coding interference contrast imaging systems An interference contrast imaging system images phase objects. The system includes an illumination source, illumination optics, polarizing optics for splitting the illumination into orthogonal polarizations and for recombining the polarizations, objective optics that... | 06/08/2010 |
| 7705970 | Method and system for optical imaging and ranging The distance of objects to an optical system is estimated. An optical mask such as a diffractive optical element, continuous phase mask, hologram, amplitude mask, or combination thereof is placed within the optics in front of a sensor array such as a CCD, CID or COM... | 04/27/2010 |
| 7660698 | Phytometric intelligence sensors Methods and apparatus for determining when plants require watering, and methods of attending to the watering of plants including signaling the grower that the plants are in need of hydration are provided. The novel methods include real-time measurement of plant meta... | 02/09/2010 |
| 7612733 | Transition region for use with an antenna-integrated electron tunneling device and method An electron tunneling device includes a first non-insulating strip and a second non-insulating strip spaced apart from one another such that first and second end portions, respectively, of the first and second non-insulating strips cooperate to form an antenna havin... | 11/03/2009 |
| 7608611 | Hsp90 inhibitors, methods of making and uses therefor The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of s... | 10/27/2009 |
| 7595060 | Yeast-antigen compositions methods of making the same Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an imm... | 09/29/2009 |
| 7572908 | Cleavable linkers for polynucleotides In various embodiments of the invention, novel compositions having a polynucleotide bound to a substrate via a cleavable linker are provided, and methods of cleaving a polynucleotide from a substrate are provided. ... | 08/11/2009 |
| 7572907 | Methods and compounds for polynucleotide synthesis Methods of forming polynucleotides are disclosed. ... | 08/11/2009 |
| 7510710 | Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a UCP and/or Fas antibody or other inhibitor, or combination thereof, and a therapeutically acceptable amount of a fatty acid metabolism inhibitor and/or a the... | 03/31/2009 |
| 7485307 | Human cystathionine β-synthase variants and methods of production thereof Human cystathionine β-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β-synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a va... | 02/03/2009 |
| 7470431 | Use of neurotoxin therapy for treatment of urological-neurological disorders associated with prostate cancer The present invention related to methods for treating neurological-urological conditions associated with prostate cancer or methods of treatment of prostate cancer, which is accomplished by administration of botulinum toxin to the patient. ... | 12/30/2008 |
| 7455845 | Use of neurotoxin therapy for treatment of urologic and related disorders related to lowering elevated bladder pressure The present invention related to methods for treating neurological-urological conditions, including urinary retention. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with urinary retention, including the bladder... | 11/25/2008 |
| 7449192 | Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic bladder dysfunction The present invention related to methods for treating neurological-urological conditions, including neurogenic bladder dysfunction. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with a neurogenic bladder dysfun... | 11/11/2008 |
| 7445794 | Methods for treating human proliferative diseases, with a combination of fatty acid metabolism inhibitors and glycolytic inhibitors The present invention generally relates to systems and methods for treating inflammatory and proliferative diseases, and wounds, using a combination of (1) fatty acid metabolism inhibitors and (2) glycolytic inhibitors and/or UCP and/or Fas inhibitors or antibodies.... | 11/04/2008 |
