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| Number | Title | Issue Date |
| 7312081 | Genetic demonstration of requirement for nkx6.1, nkx2.2 and nkx6.2 in ventral neuron generation This invention provides a method of converting a stem cell into a ventral neuron which comprises introducing into the stem cell a nucleic acid which expresses homeodomain transcription factor Nkx6.1 or Nkx6.2 protein in the stem cell so as to thereby convert the ste... | 12/25/2007 |
| 6892139 | Determining the functions and interactions of proteins by comparative analysis The invention provides novel methods for characterizing the function of nucleic acids and polypeptides. The invention provides a novel method for identifying a nucleic acid or a polypeptide sequence that may be a target for a drug. The invention provides a novel met... | 05/10/2005 |
| 6355440 | Assays using receptors for fibroblast growth factors The present invention relates to receptors for growth factors, specifically to the fibroblast growth factor receptor (FGF-R). More particularly, it provides various purified fibroblast growth factor receptor proteins, nucleic acids encoding the receptor p... | 03/12/2002 |
| 5850352 | Immersive video, including video hypermosaicing to generate from multiple video views of a scene a three-dimensional video mosaic from which diverse virtual video scene images are synthesized, including panoramic, scene interactive and stereoscopic images Immersive video, or television, images of a real-world scene are synthesized, including on demand and/or in real time, as are linked to any of a particular perspective on the scene, or an object or event in the scene. Synthesis is in accordance with user-... | 12/15/1998 |
| 5843943 | Compounds for inhibition of ceramide-mediated signal transduction Novel, heterocyclic compounds having at least one ring nitrogen, disclosed side chains and, in some embodiments, an oxygen ortho to the ring nitrogen inhibit inflammatory responses associated with TNF- and fibroblast proliferation in vivo and in vi... | 12/01/1998 |
| 5840482 | Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ A method for producing a Y chromosome specific probe selected from highly repeating sequences on that chromosome is described. There is little or no nonspecific binding to autosomal and X chromosomes, and a very large signal is provided. Inventive primers... | 11/24/1998 |
| 5840498 | Antibiotic cryptdin peptides and methods of their use The present invention provides substantially purified cryptdin peptides having a consensus amino acid sequence: X1 -C-X2 -C-R-X3 -C-X4 -E-X5 -C-X6 -C-C-X7 wherein X1 is 3 t... | 11/24/1998 |
| 5830255 | Formulation of phosphorus fertilizer for plants Concentrated phosphorus fertilizers are disclosed that comprise a buffered composition of an organic acid and salts thereof and a phosphorous-containing acid and salts thereof. The concentrated phosphorus fertilizers can be diluted with water of pH rangin... | 11/03/1998 |
| 5804566 | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides The invention is directed to methods for introducing biologically active peptides into a host by administration of polynucleotides which operatively encode for the peptide of interest. In a preferred embodiment of the invention, a mammal is desensitized t... | 09/08/1998 |
| 5794113 | Simultaneous synthesis and densification by field-activated combustion A method for preparing a highly dense product from a powdered mixture of reactants, whereby simultaneous application of a high current and pressure enables synthesis and densification of a variety of high temperature materials. The combination of field-ac... | 08/11/1998 |
| 5789655 | Transgenic animals expressing artificial epitope-tagged proteins DNA constructs are provided of epitope-tagged proteins or protein fragments which are conveniently purified with immunoaffinity chromatography such as epitope-tagged prion proteins (PrP). Transgenic animals expressing an epitope-tagged protein are provide... | 08/04/1998 |
| 5763740 | Method of detecting prions in a sample and transgenic animal used for same The invention includes an artificial PrP gene, a transgenic animal containing a PrP gene of another animal or the artificial PrP gene, a hybrid non-human mammal with an ablated endogenous prion gene and exogenous prion gene and assay methodology which use... | 06/09/1998 |
| 5745126 | Machine synthesis of a virtual video camera/image of a scene from multiple video cameras/images of the scene in accordance with a particular perspective on the scene, an object in the scene, or an event in the scene Each and any viewer of a video or a television scene is his or her own proactive editor of the scene, having the ability to interactively dictate and select--in advance of the unfolding of the scene and by high-level command--a particular perspective by w... | 04/28/1998 |
| 5734498 | Illuminator elements for conventional light microscopes An inexpensive, simple and easy-to-use illuminator element--consisting of chromophores, particularly fluorophores, and/or light-scattering bodies in a stable, typically a polymer plastic, matrix--completely replaces an infinite set of condensers for a opt... | 03/31/1998 |
| 5721118 | Mammalian artificial chromosomes and methods of using same The present invention provides a mammalian artificial chromosome (MAC), comprising a centromere and a unique cloning site, said MAC containing less than 0.1% of the DNA present in a normal haploid genome of the mammalian cell from which the centromere was... | 02/24/1998 |
| 5721098 | Comparative genomic hybridization Disclosed are new methods comprising the use of in situ hybridization to detect abnormal nucleic acid sequence copy numbers in one or more genomes wherein repetitive sequences that bind to multiple loci in a reference chromosome spread are either substant... | 02/24/1998 |
| 5707632 | Receptors for fibroblast growth factors A fibroblast growth factor (FGF) receptor including a basic fibroblast growth factor receptor has been purified. Various forms have been identified including soluble forms lacking any transmembrane segment. DNA sequences encoding full-length fibroblast gr... | 01/13/1998 |
| 5695624 | Solid state oxygen sensor A potentiometric oxygen sensor is formed having a logarithmic response to a differential oxygen concentration while operating as a Nernstian-type sensor. Very thin films of mixed conducting oxide materials form electrode services while permitting diffusio... | 12/09/1997 |
| 5686243 | Template-directed ligation and amplification assay A method for the detection of a target polynucleotide sequence wherein the target polynucleotide sequence is used as a template to direct hybridization of first and second polynucleotide probes to contiguous portions of the target. The hybridized probes a... | 11/11/1997 |
| 5685362 | Storage capacity in hot dry rock reservoirs A method of extracting thermal energy, in a cyclic manner, from geologic strata which may be termed hot dry rock. A reservoir comprised of hot fractured rock is established and water or other liquid is passed through the reservoir. The water is heated by ... | 11/11/1997 |
| 5679647 | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides The invention is directed to methods for introducing biologically active peptides into a host by administration of polynucleotides which operatively encode for the peptide of interest. In a preferred embodiment of the invention, a host who has been identi... | 10/21/1997 |
| 5677130 | BCL-1 locus nucleic acid probes and assay methods Nucleic acid probes substantially complementary to nucleic acid sequences within the bcl-1 locus are disclosed as well as polymerase chain reaction (PCR) primers substantially complementary to nucleic acid sequences within that locus that are useful in de... | 10/14/1997 |
| 5670712 | Method and apparatus for magnetic force control of a scanning probe A method and apparatus of magnetic force control for a scanning probe, wherein a first magnetic source having a magnetic moment is provided on the scanning probe and a second magnetic source is disposed external to the scanning probe to apply a magnetic f... | 09/23/1997 |
| 5631390 | Halogenation of cobalt dicarbollide A method for selectively adding chlorine, bromine, or iodine to cobalt dicarbollide anions by means of electrophilic substitution reactions. Halogens are added only to the B10 and B10' positions of the anion. The process involves use of hypohalous acid or... | 05/20/1997 |
| 5622713 | Method of detoxifying animal suffering from overdose A method for accumulating drugs or other chemicals within synthetic, lipid-like vesicles by means of a pH gradient imposed on the vesicles just prior to use is described. The method is suited for accumulating molecules with basic or acid moieties which ar... | 04/22/1997 |
| 5595834 | Annular feed air breathing fuel cell stack A stack of polymer electrolyte fuel cells is formed from a plurality of unit cells where each unit cell includes fuel cell components defining a periphery and distributed along a common axis, where the fuel cell components include a polymer electrolyte me... | 01/21/1997 |
| 5585641 | Large area, surface discharge pumped, vacuum ultraviolet light source Large area, surface discharge pumped, vacuum ultraviolet (VUV) light source. A contamination-free VUV light source having a 225 cm2 emission area in the 240-340 nm region of the electromagnetic spectrum with an average output power in this band... | 12/17/1996 |
| 5583202 | Antigenized antibodies and genes Antigenized antibodies which have inserted within their third complementarity determining regions, antigenic epitopes not found in immunoglobulins are described.... | 12/10/1996 |
| 5565186 | Method of detecting prions in a sample and transgenic animal used for same Prions are protein based infectious material that cause of variety of diseases such as Scrapie, bovine spongiform encephalopathy (also known as "Mad Cow" disease), Creutzfeldt Jakob Disease, Kuru, and fatal familial insomnia. The invention is directed to ... | 10/15/1996 |
| 5550892 | Enhanced local tomography Local tomography is enhanced to determine the location and value of a discontinuity between a first internal density of an object and a second density of a region within the object. A beam of radiation is directed in a predetermined pattern through the re... | 08/27/1996 |
| 5545894 | Compact hydrogen/helium isotope mass spectrometer The compact hydrogen and helium isotope mass spectrometer of the present invention combines low mass-resolution ion mass spectrometry and beam-foil interaction technology to unambiguously detect and quantify deuterium (D), tritium (T), hydrogen molecule (... | 08/13/1996 |
| 5538005 | B'method for monitoring fetal characteristics by radiotelemetric transmission A fetal monitor is provided for gathering characteristic data such as fetal electrocardiogram, temperature and intra-uterine pressure so that fetal health may be determined during intra-operative and postoperative periods. The fetal monitor comprises a re... | 07/23/1996 |
| 5527882 | Polypeptide having an amino acid replaced with N-benzylglycine The present invention relates to one or more polypeptides having useful biological activity in a mammal, which comprise: a polypeptide related to bradykinin of four to ten amino acid residues wherein one or more specific amino acids in the polypeptide chain ar... | 06/18/1996 |
| 5525322 | Method for simultaneous recovery of hydrogen from water and from hydrocarbons Method for simultaneous recovery of hydrogen and hydrogen isotopes from water and from hydrocarbons. A palladium membrane, when utilized in cooperation with a nickel catalyst in a reactor, has been found to drive reactions such as water gas shift, steam r... | 06/11/1996 |
| 5498259 | Method for fusing bone Method for fusing bone. The present invention is a method for joining hard tissue which includes chemically removing the mineral matrix from a thin layer of the surfaces to be joined, placing the two bones together, and heating the joint using electromagn... | 03/12/1996 |
| 5477156 | Detonation wave detection probe including parallel electrodes on a flexible backing strip A device for sensing the occurrence of destructive events and events involving mechanical shock in a non-intrusive manner. A pair of electrodes is disposed in a parallel configuration on a backing strip of flexible film. Electrical circuitry is used to se... | 12/19/1995 |
| 5462809 | Giant magnetoresistant single film alloys A single layer film is deposited onto a substrate at room temperature from two sources, one source being a magnetic material, the other being a non-magnetic or weakly-magnetic material. The film is annealed for predetermined time in order to induce phase ... | 10/31/1995 |
| 5456082 | Pin stack array for thermoacoustic energy conversion A thermoacoustic stack for connecting two heat exchangers in a thermoacoustic energy converter provides a convex fluid-solid interface in a plane perpendicular to an axis for acoustic oscillation of fluid between the two heat exchangers. The convex surfac... | 10/10/1995 |
| 5453624 | Device for detection of organic solvents by silicon photoluminescence An n-type silicon (Si) wafer is galvanostatically etched in a hydrofluoric acid (HF)-containing solution while being illuminated with a 300 watt tungsten light source to form porous silicon with luminescent properties. Photoluminescence of the porous sili... | 09/26/1995 |
| 5447032 | Fluorescent refrigeration Fluorescent refrigeration is based on selective radiative pumping, using substantially monochromatic radiation, of quantum excitations which are then endothermically redistributed to higher energies. Ultimately, the populated energy levels radiatively dee... | 09/05/1995 |
