"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 8017133 | Multicomponent vaccines Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful s... | 09/13/2011 |
| 7901907 | Process for production of bacterioferritin A nucleic acid sequence encoding all or part of an 18-19 kDa Helicobater pylori protein is described to which immunoreactivity is detected in H. pylori negative individuals. A process for the production of a recombinant form of this protein and its use... | 03/08/2011 |
| 7879551 | Methods and materials for identifying polymorphic variants, diagnosing susceptibilities, and treating disease The invention is directed to materials and methods associated with polymorphic variants in two enzymes involved in folate-dependent and one-carbon metabolic pathways: MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase,... | 02/01/2011 |
| 7709008 | Polypeptides and polynucleotides from coagulase-negative staphylococci Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective ... | 05/04/2010 |
| 7569470 | Method of forming conducting nanowires A method of preparing an array of conducting or semi-conducting nanowires may include forming a vicinal surface of stepped atomic terraces on a substrate, and depositing a fractional layer of dopant material to form nanostripes having a width less than the width of ... | 08/04/2009 |
| 7473762 | Proteins and polypeptides from coagulaslase-negative staphylococci Proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are provided which are useful in the prevent... | 01/06/2009 |
| 7438858 | Dispensing assembly for liquid droplets A dispensing assembly for liquid droplets that includes a dispenser connected to a liquid carrying pipe which in turn is connected to a source of pressurized liquid. The dispenser has an elongated body member having a main bore connected to the liquid carrying pipe.... | 10/21/2008 |
| 7378397 | TRH-degrading ectoenzyme inhibitors Peptide derivatives useful as inhibitors of activity of thyrotropin-releasing hormone-degrading ectoenzyme (TRH-DE) are of formula Ia: wherein: R1 is an optionally su... | 05/27/2008 |
| 7368112 | fibrinogen binding protein gene The isolation of genes and proteins from Staphylococcus aureus is provided, and the nucleic acids coding for specific regions of the S. aureus CIfA protein are described. The nucleic acids encode proteins that can be useful as vaccines or in pharmaceut... | 05/06/2008 |
| 7122301 | Method of assaying cellular adhesion with a coated biochip Biological assays using various constructions of biochips are disclosed to mirror in vivo situations. The biochip 50 comprises a microchannel 51 having a liquid outlet port 1, bubble release port 2 and a liquid outlet port 3 with a... | 10/17/2006 |
| 6994855 | fibrinogen binding protein gene The invention relates to the isolation of the fibrinogen binding protein gene from Staphylococcus aureus and to the use of the fibrinogen binding protein and antibodies generated against it for wound healing, blocking adherence to indwelling medical devices, ... | 02/07/2006 |
| 6940883 | Laser diode A laser diode (1) for outputting light of a single mode comprises a substrate layer (5), a cladding layer (6) and a compound light propagating layer (7) comprising first, second, third and fourth layers (9 to 12). A wave gui... | 09/06/2005 |
| 6841154 | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and Staphylococcus aureus Polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positive staphylococcus bacteria, such as S. aureus and to coagulase-negative bacteria, such as S. epidermidis and S. hemolyticus, are provided which can recognize s... | 01/11/2005 |
| 6805841 | Liquid pumping system A liquid outlet link assembly is provided for liquid delivery output rates below 10 μl per minute so as to smooth out the flow from a positive displacement pump which has an immediate step pumping rate which is relatively substantially larger than the delivery rate... | 10/19/2004 |
| 6804272 | Self-pulsating laser diode and a method for causing a laser diode to output light pulses A semiconductor self-pulsating laser diode (1) comprises a wave guiding layer (2) sandwiched between lower and upper cladding layers (4, 5). A current blocking layer (8) defining a slot (10) through which pumping current is directe... | 10/12/2004 |
| 6770434 | Biological assay method Biological assays using various constructions of biochips are disclosed to mirror in vivo situations. The biochip 50 comprises a microchannel 51 having a liquid outlet port 1, bubble release port 2 and a liquid outlet port 3 with a... | 08/03/2004 |
| 6713021 | Dispensing method and assembly for liquid droplets A dispensing assembly for liquid droplets that includes a dispenser connected to a liquid carrying pipe which in turn is connected to a source of pressurized liquid. The dispenser has an elongated body member having a main bore connected to the liquid carrying pipe.... | 03/30/2004 |
| 6635473 | Polypeptides and polynucleotides from coagulase-negative staphylococci Isolated proteins, designated SdrF, SdrG and SdrH, and their corresponding amino acid and nucleic acid sequences are provided which are useful in the prevention and treatment of infection caused by coagulase-negative staphylococcal bacteria such as S. epi... | 10/21/2003 |