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Assignee: The Ohio State University


Location: Columbus, OH
No. of patents: 282

1                
NumberTitleIssue Date
8183365Synthetic method for ceratamine A and B and analogs thereof
Methods are provided for preparing compounds of the general formula (I) wherein X1 is an aryl hydrocarbon group optionally substituted with one or more groups independently selected from —R, —NH2, ...
05/22/2012
8177890Stable supported Pd-alloy membranes
A Pd alloy membrane and method of making are described. ...
05/15/2012
8172900Microsensor system for application in biomechanics
A sensing system and method to detect and determine magnitude and direction of ciliary body movement within an eye of a patient is disclosed. The invention comprises a permanent magnet (PM) positioned in the ciliary body, and a sensing device (SD) positioned adjacen...
05/08/2012
8148069MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of solid cancers
The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provide methods of identifying inhibitors of tumorigenesis. ...
04/03/2012
8143337Method of preparing a composite with disperse long fibers and nanoparticles
A composite material having polymeric resin with disperse phases of reinforcing fibers and nanoparticle materials and its manufacture is disclosed herein. The nanoparticles may be bound together and added to the polymeric resin as microscale aggregations, and then u...
03/27/2012
8137751Hierarchical structures for superhydrophobic surfaces and methods of making
Embodiments of methods of making superhydrophobic structures comprise depositing a polymer mold onto a silicon surface comprising a plurality of microasperities, removing the polymer mold after the polymer mold has hardened, depositing a liquid epoxy resin into the ...
03/20/2012
8131043Method and apparatus for detecting interventricular dyssynchrony
Several embodiments of a method and apparatus for detecting interventricular dyssynchrony are provided. In one embodiment, the apparatus includes an image segment processor and an image classifier. The image segment processor may segment left and right ventricles in...
03/06/2012
8119101Anti-CD74 immunoconjugates and methods of use
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more anti-CD74 antibodies or antigen-binding fragments thereof, conjugated to a li...
02/21/2012
8110657Polypeptides and polynucleotides for enhancing immune reactivity to HER-2 protein
Compositions for stimulating the immune system and for treating malignancies associated with overexpression of the HER-2 protein are provided. Such compositions include immunogenic epitopes of the HER-2 proteins and chimeric and multivalent peptides which comprise s...
02/07/2012
8084710Low-temperature laser spot impact welding driven without contact
A laser, aimed at a flyer plate tab, causes optical energy to be directed at the tab, specifically, at a top surface thereof. Energy impacting the tab accelerates the tab out of an initial bent position, straightening it into an impact with a target sheet. The impac...
12/27/2011
8038990Compositions and methods for the prevention and removal of biofilms on inert and biological surfaces
Organisms, compositions, and methods for at least partially reducing the formation of a biofilm and/or at least partially removing a biofilm are provided. The organisms, compositions, and methods may be used on biotic and abiotic surfaces. ...
10/18/2011
8022227Method of synthesizing 1-indazole compounds
A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles. ...
09/20/2011
7993271System and method for screening tissue
A system and method for screening tissue is provided. The system provides a computer-based system for distinguishing between normal and potentially abnormal tissue. The system includes computer components for generating and receiving ultrasonic waves, for storing a ...
08/09/2011
7992569Customized transition zone system and method for an ablation pattern
The present invention discloses a corneal refractive procedure providing a customized transition zone. The customized transition zone provided according to the methods and systems of the present invention exhibits continuous curvature between an ablated optical zone...
08/09/2011
7977508Methods for synthesizing ammonia borane
Methods of synthesizing ammonia borane are provided. The methods comprise reacting at least one amine borane with ammonia such that ammonia borane is produced. Ammonia borane has a chemical formula Of NH3—BH3 and provides a good source of sto...
07/12/2011
7970048Method of systematic construction of space-time constellations, system and method of transmitting space-time constellations
Space-time code, and methods for constructing space-time codes are provided. The space-time coder performs a respective linear transformation on each of P sets of K modulated symbols of a modulated symbol stream to produce P sets of T linearly transformed symbols, a...
06/28/2011
7967979Bi-phasic bioretention system
An anaerobic to aerobic sequence enhances biological degradation of many organic pollutants. Exemplary embodiments provide systems and methods for effective treatment of storm-water runoff pollutants such as hydrocarbons, nitrates, phosphorus, and heavy metals using...
06/28/2011
7921949All wheel drive electrically-variable transmission
A transaxle (200) operatively connects a first associated rotational connection and a second associated rotational connection with an associated vehicle axle. An electrically-variable transmission includes an engine (108), a first electric machine (...
04/12/2011
7911671Apparatus and method for providing true time delay in optical signals using a Fourier cell
An true time delay in optical signals using a Fourier cell is provided. One embodiment includes: an input array for inputting an array of light beams; at least a portion of a lens; a plurality of micromirrors located at a distance away from the lens that is approxim...
03/22/2011
7909505Method and device for investigation of phase transformations in metals and alloys
A device and method for investigating phase transformation properties and structural changes of materials. In one form, the device simulates actual thermal processing conditions, while the method can be used in both simulations as well as in actual processing condit...
03/22/2011
7898493Implementation of ultra wide band (UWB) electrically small antennas by means of distributed non foster loading
A method to design antennas with broadband characteristics. In an exemplary embodiment, a method comprises loading an antenna structure with multiple reactive loads. The multiple loads are synthesized by applying the theory of Characteristic Modes. Another exemplary...
03/01/2011
7897150Canine lymphoma cell line and uses thereof
An isolated canine peripheral T-cell lymphoma cell line, where the cell line is a canine-lymphoma cell line and uses thereof are disclosed. An isolated canine peripheral T-cell lymphoma cell line where the cell line is the canine-lymphoma cell line designated OSW (A...
03/01/2011
7837975High purity, high pressure hydrogen production with in-situ COand sulfur capture in a single stage reactor
A process for producing hydrogen, comprising the steps of: (a) gasifying a fuel into a raw synthesis gas comprising CO, hydrogen, steam and sulfur and halide contaminants in the form of H2S, COS and HX, where X is a halide; (b) passing the raw synthesis g...
11/23/2010
7790172Methods for reducing nasopharyngeal colonization of non-typable with synthetic chimeric fimbrin peptides
The present invention provides synthetic chimeric fimbrin peptides which induce an immunogenic response in animals to non-typable Haemophilus influenzae and that do not require tedious purification techniques. The synthetic chimeric fimbrin peptides reduce th...
09/07/2010
7767424Cloning and characterization of the broad-spectrum resistance gene PI2
Methods for enhancing or creating plant disease resistance to plant pests are provided. Transforming a plant with a novel rice Pi2-like disease resistance gene of the invention enhances disease resistance of the plant. ...
08/03/2010
7767191Combustion looping using composite oxygen carriers
A method for producing hydrogen gas is provided and comprises reducing a metal oxide in a reduction reaction between a carbon-based fuel and a metal oxide to provide a reduced metal or metal oxide having a lower oxidation state, and oxidizing the reduced metal or me...
08/03/2010
7745820Negative differential resistance polymer devices and circuits incorporating same
A device includes: a first electrical contact; a second electrical contact; a semiconducting or semimetallic organic layer disposed at least partially between the first and second electrical contacts; and a tunneling barrier layer disposed at least partially between...
06/29/2010
7745132Prognostic indicators of canine lymphoid neoplasia using tumor-derived plasma DNA
A method of identifying an animal having a disease or condition without clinical symptoms includes detecting an elevated level of plasma DNA from blood or a blood fraction from the animal. In particular, the disease or condition can be a lymphoid neoplastic disease....
06/29/2010
7743967Chromium-free welding consumable
A chromium-free welding consumable and a method of welding stainless steel to reduce the presence of chromium emissions. The consumable is made from an alloy that reduces the emission of chromium during a welding process, and include predominantly nickel, with betwe...
06/29/2010
7722842Carbon dioxide sequestration using alkaline earth metal-bearing minerals
A method for mineral sequestration of pollutant gases resulting from the combustion of carbon-based fuels such as carbon and sulfur dioxides is provided and includes, providing a particulate magnesium-containing mineral and exposing the magnesium-containing mineral ...
05/25/2010
7678351High temperature COcapture using engineered eggshells: a route to carbon management
Applying an acid treatment to eggshells provides a sorbent with unexpectedly high CO2 capture capacity and ability to regenerate. ...
03/16/2010
7669404Localized arc filament plasma actuators for noise mitigation and mixing enhancement
A device for controlling fluid flow. The device includes an arc generator coupled to electrodes. The electrodes are placed adjacent a fluid flowpath such that upon being energized by the arc generator, an arc filament plasma adjacent the electrodes is formed. In tur...
03/02/2010
7666430Polypeptides and polynucleotides for enhancing immune reactivity to HER-2 protein
Compositions for stimulating the immune system and for treating malignancies associated with overexpression of the HER-2 protein are provided. Such compositions include immunogenic epitopes of the HER-2 proteins and chimeric and multivalent peptides which comprise s...
02/23/2010
7660499Optical spot displacement apparatus
Optical spot displacement apparatus comprises a face that is divided into a plurality of columns; each column of the plurality including a predetermined number of prisms, the predetermined number of prisms of a same column configured within the corresponding column ...
02/09/2010
7657309Measuring human heart muscle viability using myocardial electrical impedance
A method for detecting a quantitative measure of a physiologic state of a human myocardium or coronary artery. Implementations of the method detect the extent of change of myocardial electrical impedance from a mean baseline value to provide diagnosis of the extent ...
02/02/2010
7633670Methods, systems, and devices for steering optical beams
Devices and methods are provided for steering optical beams. The devices use arrays and at least one optical element to steer an input beam to a desired location. Additionally, devices and methods are provided for changing the array dimensions of arrays of input bea...
12/15/2009
7630598Apparatus and method for providing an optical cross-connect
An optical cross-connect for shifting the location of one or more light beams in and array of light beams is provided. An exemplary embodiment of an optical cross connect includes an input array for inputting an array of light beams; at least a portion of a spherica...
12/08/2009
7618606Separation of carbon dioxide (CO) from gas mixtures
A reaction-based process has been developed for the selective removal of carbon dioxide from a multicomponent gas mixture. The proposed process effects the separation of CO2 from a mixture of gases by its reaction with metal oxides. The Calcium based Reac...
11/17/2009
7583747Method of systematic construction of space-time constellations, system and method of transmitting space-time constellations
Space-time code, and methods for constructing space-time codes are provided. The space-time coder performs a respective linear transformation on each of P sets of K modulated symbols of a modulated symbol stream to produce P sets of T linearly transformed symbols, a...
09/01/2009
7566787Small molecule cyclin D1 ablative agents
Cyclin D1 ablative agents and methods of using these agents in the treatment of cancers, and particularly breast cancer. Also provided are methods of treating cancer, the method comprising administering a therapeutically effective amount of one of the cyclin D1 abla...
07/28/2009
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