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Assignee: The Johns Hopkins University


Location: Not specified.
No. of patents: 6

NumberTitleIssue Date
6916490Controlled release of bioactive substances
The present invention contemplates in part coacervates in which a bioactive substance and delivery agent are encapsulated therein for controlled release. In certain embodiments, said bioactive substance and delivery agent are a viral vector and virus, respectively. ...
07/12/2005
6662805Method for composite cell-based implants
This invention is a method for the implantation of a combination of cells or cell-microcarrier aggregates wherein one component comprises a solid implantable construct and a second component comprises an injectable formulation. For example, in one embodim...
12/16/2003
6127126Method for diagnosing glioma associated with structural alterations of the EGF receptor gene in human tumors
Deletions in the EGF-R gene are found in many gliomas, breast tumors, and lung tumors. A particular truncated EGFR protein has been found in many tumors and provides diagnostic and therapeutic modalities....
10/03/2000
6114124Detection of APC proteins
A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer pati...
09/05/2000
5874235Screening assays for cancer chemopreventative agents
Nonsteroidal anti-inflammatory drugs cause a dramatic increase in intracellular ceramide, which induces apoptosis. The ceramide increase is likely mediated by cyclooxygenase inhibition, which elevates arachidonic acid, which stimulates sphingomyelinase, w...
02/23/1999
5830676Diagnosis with MCC
A new human gene termed MCC is disclosed. Antibody based methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expr...
11/03/1998
 
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