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Assignee: The George Washington University


Location: Washington, DC
No. of patents: 43

1    
NumberTitleIssue Date
8184351Amplified bimorph scanning mirror, optical system and method of scanning
An amplified bimorph scanning mirror for use in various optical systems, an optical coherence tomography scanner incorporating the amplified bimorph scanning mirror, and a method for manufacturing the foregoing are described. A method for optically scanning a target...
05/22/2012
8143681Saw devices, processes for making them, and methods of use
The design, fabrication, post-processing and characterization of a novel SAW (Surface Acoustic Wave) based bio/chemical sensor in CMOS technology is introduced. The sensors are designed in AMI 1.5 μm 2 metal, 2 poly process. A unique maskless post processing sequen...
03/27/2012
8140339Method and apparatus for translating hand gestures
A sign language recognition apparatus and method is provided for translating hand gestures into speech or written text. The apparatus includes a number of sensors on the hand, arm and shoulder to measure dynamic and static gestures. The sensors are connected to a mi...
03/20/2012
8110796Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays
The production and use of silicon microcolumn arrays that harvest light from a laser pulse to produce ions are described. The systems of the present invention seem to behave like a quasi-periodic antenna array with ion yields that show profound dependence on the pla...
02/07/2012
8084734Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays
The present invention provides a method of producing a laser-patterned silicon surface, especially silicon wafers for use in laser desorption ionization (LDI-MS) (including MALDI-MS and SELDI-MS), devices containing the same, and methods of testing samples employing...
12/27/2011
8067730Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry
The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI). ...
11/29/2011
8063373Compact near-IR and mid-IR cavity ring down spectroscopy device
This invention relates to a compact cavity ring down spectrometer for detection and measurement of trace species in a sample gas using a tunable solid-state continuous-wave mid-infrared PPLN OPO laser or a tunable low-power solid-state continuous wave near-infrared ...
11/22/2011
8051697Self calibration devices for chemical and bio analytical trace detection systems
The present invention relates to chemical and bioanalytical sensors and sensor systems, particularly to systems incorporating a calibration device for sensors where the calibration device is comprised of an array of micromachined MEMS structures and materials for tr...
11/08/2011
8018010Circular surface acoustic wave (SAW) devices, processes for making them, and methods of use
The design, fabrication, post-processing and characterization of a novel circular design SAW (Surface Acoustic Wave) based bio/chemical sensor in CMOS technology is introduced. The sensors are designed in AMI 1.5 μm 2 metal, 2 poly process. A unique maskless post p...
09/13/2011
7999945Optical coherence tomography / acoustic radiation force imaging probe
A combined system and method synchronizes optical coherence tomography and acoustic radiation force for simultaneously imaging and mechanically displacing tissue in a patient as a detection and analytic tool. An endoscope is provided which has a piezoelectric elemen...
08/16/2011
7964843Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry
The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI). ...
06/21/2011
7829139Method of making nanoparticle wires
A new method of making self-assembled nanoparticle wires involves: (1) at about ambient temperature and at or near atmospheric pressure, immersing a hydrophilic solid substrate at a non-horizontal angle (e.g., vertically) into a su...
11/09/2010
7804064In-situ droplet monitoring for self-tuning spectrometers
A laser scattering based imaging technique is utilized in order to visualize the aerosol droplets in an inductively coupled plasma (ICP) torch from an aerosol source to the site of analytical measurements. The resulting snapshots provide key information about the sp...
09/28/2010
7735146Protein microscope
A system and method for analyzing and imaging a sample containing molecules of interest combines modified MALDI mass spectrometer and SNOM devices and techniques, and includes: (A) an atmospheric-pressure or near-atmospheric-pressure ionization region; (B) a sample ...
06/08/2010
7573627Amplified bimorph scanning mirror, optical system and method of scanning
An amplified bimorph scanning mirror for use in various optical systems, an optical coherence tomography scanner incorporating the amplified bimorph scanning mirror, and a method for manufacturing the foregoing are described. A method for optically scanning a target...
08/11/2009
7569823Compact near-IR and mid-IR cavity ring down spectroscopy device
This invention relates to a compact cavity ring down spectrometer for detection and measurement of trace species in a sample gas using a tunable solid-state continuous-wave mid-infrared PPLN OPO laser or a tunable low-power solid-state continuous wave near-infrared ...
08/04/2009
7565295Method and apparatus for translating hand gestures
A sign language recognition apparatus and method is provided for translating hand gestures into speech or written text. The apparatus includes a number of sensors on the hand, arm and shoulder to measure dynamic and static gestures. The sensors are connected to a mi...
07/21/2009
7541586Compact near-IR and mid-IR cavity ring down spectroscopy device
This invention relates to a compact cavity ring down spectrometer for detection and measurement of trace species in a sample gas using a tunable solid-state continuous-wave mid-infrared PPLN OPO laser or a tunable low-power solid-state continuous wave near-infrared ...
06/02/2009
7531273Fullerene-based secondary cell electrodes
A composition for forming an electrode for a lithium ion secondary battery includes a carbonaceous material combined with a fullerene material including fullerene species having a carbon content of Cn, where n≧100. The composition is heated to a tempera...
05/12/2009
7483767Feedback mechanism for smart nozzles and nebulizers
Nozzles and nebulizers able to produce aerosol with optimum and reproducible quality based on feedback information obtained using laser imaging techniques. Two laser-based imaging techniques based on particle image velocimetry (PTV) and optical patternation map and ...
01/27/2009
7317186Short torch design for direct liquid sample introduction using conventional and micro-nebulizers for plasma spectrometry
An apparatus and method for providing direct liquid sample introduction using a nebulizer are provided. The apparatus and method include a short torch having an inner tube and an outer tube, and an elongated adapter having a cavity for receiving the nebulizer and po...
01/08/2008
7303752Hookworm vaccine
Preparations which elicit an immune response to hookworm antigens and which may be utilized as hookworm vaccines are provided. In addition, a method of increasing the effectiveness of vaccinations against infectious diseases in patients infected with hookworm is pro...
12/04/2007
7145137Demountable direct injection high efficiency nebulizer for inductively coupled plasma mass spectrometry
A nebulizer adapted for adjusting a position of a capillary tube contained within the nebulizer is provided. The nebulizer includes an elongated tubular shell having a gas input port and a gas output port, a capillary adjustment adapter for displacing the capillary ...
12/05/2006
6663991Fuel cell pressurization system
A thermally energized fuel-cell pressurization system and humidity control system utilizing a compressor-expander, an ejector, and a steam generator is disclosed. The system can be more compact and energy efficient than comparable electrically-based press...
12/16/2003
6635628Methods of administering camptothecin compounds for the treatment of cancer with reduced side effects
Methods of administering camptothecin compounds such as irinotecan hydrochloride to reduce a diarrhea side effect and methods of treating cancer and AIDs with camptothecin compounds including administering the camptothecin compounds while maintaining the ...
10/21/2003
6407117Method of administering camptothecin compounds for the treatment of cancer with reduced side effects
Methods of administering camptothecin compounds such as irinotecan hydrochloride to reduce a diarrhea side effect and methods of treating cancer and AIDs with camptothecin compounds including administering the camptothecin compounds while maintaining the ...
06/18/2002
6355416Assay for the measurement of DNA synthesis rates
Use of nonradioactive tracer technology used to measure DNA synthesis rates. DNA synthesis is determined by administering one or more stable isotope labelled precursors to one or more of DNA molecules and the amount of the stable isotope label in the DNA ...
03/12/2002
6219988Wrapping system for strengthening structural columns or walls
A method of reinforcing a substantially vertical support structure comprising the steps of: wrapping at least one sheet of resin impregnated high strength fiber around the support structure to form a multi-layer wrap, and then interposing a substantially ...
04/24/2001
6184863Direct pointing apparatus and method therefor
The direct pointing apparatus and method therefor has a light sensing arrangement including a plurality of light receivers positioned around the outer periphery of a computer display and A/D interface circuitry coupling the light receivers to a host compu...
02/06/2001
6145071Multi-layer multi-processor information conveyor with periodic transferring of processors' states for on-the-fly transformation of continuous information flows and operating method therefor
In a multi-processor computing system, a multi-layer architecture is described in which each layer has a plurality of dual ported microprocessors, one port of which receives data for processing and the other port of which is utilized for unloading or pass...
11/07/2000
6138456Pressure exchanging ejector and methods of use
A novel pressure-exchange ejector is disclosed whereby a high energy primary fluid compresses a lower energy secondary fluid through direct fluid-fluid momentum exchange. The pressure-exchange ejector utilizes non-steady flow principles and supersonic flo...
10/31/2000
6121328Racemic propranolol
Pharmaceutical formulations of mixtures of the D and L configuration of propranolol are disclosed which have antioxidant activity and reduced ଲ blocking activity....
09/19/2000
6100297Intravenous magnesium gluconate for treatment of conditions caused by excessive oxidative stress due to free radical distribution
The intravenous use of magnesium gluconate to substantially block free radical surge in the treatment of ischemia/reperfusion (I/R) injury due to oxidative stress....
08/08/2000
6077525Use of conjugated linoleic acids
The use of conjugated linoleic acid to inhibit cyclooxygenase-catalyzed conversion of arachidonic acid, thromboxane formation and platelet aggregation....
06/20/2000
5935860Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia
The invention relates to methods for identifying prostatic intraepithelial neoplasia by determining the uteroglobin concentration in a tissue sample....
08/10/1999
5919934Compounds, compositions, and methods for cancer imaging and therapy
Disclosed are bisaminothiol and amino compounds with appended pharmacophores, complexes of these compounds with 99m Tc(V)0, Re(V)0, In+3, 67 Ga+3, 90 Y+3, 109 Pd+2 or ...
07/06/1999
5776985Fluorinated propranolol and related methods
Fluorinated beta blockers, such as propranolol, are presented with amplified antioxidant effects and various levels of beta blocking effects. Mixtures are also presented of fluorinated antioxidant drugs, such as propranolol, with fluorinated antioxidant n...
07/07/1998
5721211Compositions and methods for treating small cell and nonsmall cell lung cancers
Compositions and methods of use thereof for treating small cell and nonsmall cell lung cancers in mammals are disclosed. The compositions comprise substances that inhibit the lung cancer cell growth and proliferation actions of the biological response mod...
02/24/1998
5647221Pressure exchanging ejector and refrigeration apparatus and method
A novel ejector, an ejector-refrigeration system, and a method of refrigeration are disclosed. The system is particularly well suited for the utilization of energy sources such as waste heat from automobile engines and solar collectors. Further, the syste...
07/15/1997
5273963Compositions and methods for treating small cell and nonsmall cell lung cancers
Compositions and methods of use thereof for treating small cell and nonsmall cell lung cancers in mammals are disclosed. The compositions comprise substances that inhibit the lung cancer cell growth and proliferation actions of the biological response mod...
12/28/1993
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