Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8143387 | Engineered antibody-stress protein fusions Provided are fusion polypeptides comprising an engineered antibody and a stress protein that bind to antigens with high affinity, are highly immunogenic, exhibit MHC class I priming and are able to be produced in non-mammalian cells, such as E. coli. ... | 03/27/2012 |
| 8114379 | Diagnostic and therapeutic alkyl piperidine/piperazine compounds and process Piperidine or piperazine compounds useful for treating neurodegenerated diseases characterized by the lack of dopamine neurons activity or for imaging the dopamine neurons are provided. The compounds are characterized by the formulae: | 02/14/2012 |
| 8092782 | Polybiotin compounds of magnetic resonance imaging and drug delivery The invention relates generally to biotin-containing compounds that are useful as imaging agents and drug-delivery agents. Another aspect of the invention relates to the aforementioned compounds chelated to a metal atom. In a preferred embodiment, the metal atom is ... | 01/10/2012 |
| 7858803 | Imaging tracers for early detection and treatment of amyloid plaques caused by Alzheimer's disease and related disorders The present invention relates to compounds and methods for imaging and treating Alzheimer's disease or an amyloidosis-associated pathological condition that utilize a novel amyloid imaging tracer for detecting amyloid deposits in a subject suffering from these condi... | 12/28/2010 |
| 7749501 | Engineered antibody-stress protein fusions Provided are fusion polypeptides comprising an engineered antibody and a stress protein that bind to antigens with high affinity, are highly immunogenic, exhibit MHC class I priming and are able to be produced in non-mammalian cells, such as E. coli. ... | 07/06/2010 |
| 7186409 | Neural stem cells and use thereof for brain tumor therapy The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering gen... | 03/06/2007 |
| 7119183 | Rapid immunoselection cloning method A simple and highly efficient method for cloning cDNAs including CD27 (SEQ ID NO:28) from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mam... | 10/10/2006 |
| 7073510 | Photochemical tissue bonding Photochemical tissue bonding methods include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tis... | 07/11/2006 |
| 7060251 | Imaging agents for early detection and monitoring of cardiovascular plaque The invention provides imaging agents comprising a label in association with a plaque specific targeting molecule. Methods for using the imaging agents to diagnose or monitor plaque formation and growth and kits containing the cardiovascular agents or components sui... | 06/13/2006 |
| 6977075 | Photosensitizer conjugates for targeting intracellular pathogens The methods of the invention can be used to treat mycobacterial infections, or any disease or disorder that is caused by (or aggravated by) an intracellular pathogen. Accordingly, the invention features methods for treating a subject who has a disorder that is assoc... | 12/20/2005 |
| 6831169 | Hepatitis C virus vaccine Nucleic acid molecule that comprise an incomplete hepatitis C viral genome are provided. Pharmaceutical compositions that contain nucleic acid molecules comprising an incomplete hepatitis C viral genome including a nucleotide sequence encoding a complete hepatitis C... | 12/14/2004 |
| 6579676 | Rapid mutational analysis method and compositions A novel rapid mutational analysis method for mapping protein epitopes is disclosed. This method has been used to identify the binding sites for 16 anti-CD2 and anti-CD4 monoclonal antibodies. The powerful, rapid, and simple method of the present invention... | 06/17/2003 |
| 6280957 | Costimulatory blockade and mixed chimerism in allo-transplantation Use of the blockade of costimulation and hematopoietic stem cells in allograft transplantation.... | 08/28/2001 |
| 6274558 | Method for treating cardiac malfunction A method of treating cardiac malfunction by administering a positive inotropic effect-producing amount of Hypothalamic Inhibitory factor (HIF).... | 08/14/2001 |
| 6265383 | Treatment of ischemic cardiac malfunction The present invention is based on the unexpected discoveries that hypothalamic inhibitory factor (HIF) has a positive inotropic effect in a whole organ preparation, such as an isolated perfused heart, and that HIF, to a greater extent than ouabain, dilate... | 07/24/2001 |
| 6235888 | Hepatitis C virus vaccine Nucleic acid molecule that comprise an incomplete hepatitis C viral genome including specifically disclosed DNA sequences are disclosed. Pharmaceutical compositions that contain nucleic acid molecules comprising an incomplete hepatitis C viral genome incl... | 05/22/2001 |
| 6218525 | Nucleic acid encoding CD28 A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA librari... | 04/17/2001 |
| 6111093 | CD19 coding sequences The present invention specifically provides the CD19 cDNA sequence.... | 08/29/2000 |
| 6063755 | Intestinal trefoil proteins Intestinal trefoil factors and nucleic acids encoding intestinal trefoil factors are disclosed. The intestinal trefoil factors disclosed are resistent to destruction in the digestive tract and can be used for the treatment of peptic ulcer diseases, inflam... | 05/16/2000 |
| 6033371 | Apparatus and method for vasodilation A method and apparatus for dilating blood vessels in vasospasm through the use of high frequency wave, e.g., hydraulic or acoustic waves. The invention is suitable to treat any vasospasm, including any vasospasm intractable to medication, including cerebr... | 03/07/2000 |
| 6025341 | Chimeric hepatitis B/hepatitis C virus vaccine Nucleic acid molecule that comprise an incomplete hepatitis C and hepatitis B viral genome including specifically disclosed DNA sequences are disclosed. Pharmaceutical compositions that contain nucleic acid molecules comprising an incomplete hepatitis C a... | 02/15/2000 |
| 6013472 | GA4 DNA, protein and methods of use The invention relates to the DNA and protein encoded by the GA4 locus. This protein is believed to be a member of the family of enzymes involved in the biosynthesis of the gibberellin family (GA) of plant growth hormones which promote various growth and d... | 01/11/2000 |
| 6004781 | Nucleic acid encoding Ig-CD4 fusion proteins The invention relates to a fusion protein which comprises an immunoglobulin of the IgM, IgG1 or IgG3 immunoglobulin class, wherein the variable region of the light or heavy chain has been replaced with CD4 or fragment thereof which is capable of binding t... | 12/21/1999 |
| 5998997 | Measuring bone mineral characteristics using differential cross polarization and adiabatic demagnetization in a rotating frame with magnetic resonance Methods and apparatus for characterizing bone mineral characteristics using differential cross polarization magnetic resonance methods are disclosed. According to one embodiment the method includes a step of producing a static magnetic field in a sample t... | 12/07/1999 |
| 5929220 | Hepadnavirus receptor The invention features a purified nucleic acid that encodes a member of the hepadnavirus family of cellular receptors. The receptor is a 170 kD cell surface glycoprotein, and is referred to as the p170 receptor. The pre-S domain of the duck hepatitis B vi... | 07/27/1999 |
| 5873359 | Methods and devices for treating pulmonary vasoconstriction and asthma A method for treating or preventing bronchoconstriction or reversible pulmonary vasoconstriction in a mammal, which method includes causing the mammal to inhale a therapeutically-effective concentration of gaseous nitric oxide or a therapeutically-effecti... | 02/23/1999 |
| 5872094 | Method for attaching cartilaginous tissue, cartilage matrix protein or link protein to a surface Link protein and cartilage matrix protein, which are two major components of the extracellular cartilage matrix, have been found to bind to each other. Cartilaginous tissue is attached to a surface by anchoring on the surface a fragment of cartilage matri... | 02/16/1999 |
| 5849898 | CD40 coding sequences A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. The present invention specifically provides the CD40 cDNA sequence.... | 12/15/1998 |
| 5847081 | Conjugate vaccine for group B Streptococcus A vaccine capable of protecting a recipient from infection caused by group B Streptococcus. The vaccine provides polysaccharide-protein moieties and contain (a) a group B Streptococcus polysaccharide conjugated to (b) a functional derivative of a group B ... | 12/08/1998 |
| 5830731 | Cloning vector, polylinker and methods A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA librari... | 11/03/1998 |
| 5820860 | Conjugate vaccine for group B streptococcus A vaccine capable of protecting a recipient from infection caused by group B Streptococcus. The vaccine provides polysaccharide-protein moieties and contain (a) a group B Streptococcus polysaccharide conjugated to (b)) a functional derivative of a group B... | 10/13/1998 |
| 5716937 | Method for treating cardiac malfunction A method of treating cardiac malfunction by administering a positive inotropic effect-producing amount of Hypothalamic Inhibitory factor (HIF).... | 02/10/1998 |
| 5648241 | Conjugate vaccine against group B streptococcus A purified DNA molecule is disclosed that comprises a DNA sequence encoding a Group B Streptococcus alpha antigen or antibody eliciting fragment. The alpha antigen sequence encodes several distinct domains including an N-terminal sequence that precedes th... | 07/15/1997 |
| 5643726 | Methods for modulating transcription from the amyloid ଲ-protein precursor (APP) promoter The application concerns methods for modulating transcription from the amyloid ଲ-protein precursor (APP) promoter. The upstream stimulatory factor (USF) is described as being capable of activating transcription from the APP promoter. Also described ... | 07/01/1997 |
| 5506126 | Rapid immunoselection cloning method A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA librari... | 04/09/1996 |
| 5501979 | Herpes simplex virus type I expression vector A recombinant HSV-1 vector capable of infecting and being propagated in a non-mitotic cell. The vector can be used to treat neurological diseases, and to produce animal and in vitro models of such diseases.... | 03/26/1996 |
| 5434775 | Managing an inventory of devices The locations of a plurality of devices are tracked using a network of communication links, each of which corresponds to a location. Each device is given a tag that identifies the device with respect to other devices and that is connectable to a communica... | 07/18/1995 |
| 5358857 | Method of preparing fusion proteins Fusion proteins are obtained in high yields if a mixed oligonucleotide is constructed which codes for the ballast constituent of the fusion protein. The oligonucleotide mixture is introduced in a vector in such a manner that it is functionally linked to a... | 10/25/1994 |
| 5322801 | Protein partner screening assays and uses thereof A rapid, simple and inexpensive method to screen and classify proteins as partners of dimeric proteins is described. The method utilizes fusion protein constructs containing a DNA binding domain and complementary dimerization domains from a different prot... | 06/21/1994 |
| 5277894 | Method for tumor detection and treatment The invention relates to a method of detecting an Fc receptor-expressing tumor site in an individual by administering to the individual a diagnostically effective amount of detectably-labeled non-specific immunoglobulin or Fc or Fc' fragment thereof, wher... | 01/11/1994 |
