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| Number | Title | Issue Date |
| 8182522 | Apparatus and method for delivering lined intraluminal prostheses An apparatus for delivering an intraluminal prosthesis within a patient's body includes an inner sheath having longitudinally spaced proximal and distal inner sheath ends, and a nose cone connected to the distal inner sheath end. An intraluminal prosthesis sheath ha... | 05/22/2012 |
| 8180601 | Systems and methods for determining volume of activation for deep brain stimulation This document discusses, among other things, systems and methods for determining volume of activation for deep brain stimulation (“DBS”) using a finite element model (FEM) circuit to determine a FEM of an implanted electrode and a tissue medium in which the elec... | 05/15/2012 |
| 8177703 | Blood pump A blood pump (26) includes a stator assembly including a fluid inlet (24) and a fluid outlet (26). A rotor assembly (120) includes an impeller (40) rotatable about an axis (44) to move fluid from the inlet (24) to the... | 05/15/2012 |
| 8167952 | Arthroplastic implant with shield for basilar joint and related methods An arthroplastic implant for a basilar joint of a hand of a patient includes a body having a distal surface and a proximal surface opposite therefrom. The distal surface is to be positioned adjacent a first metacarpal bone at the basilar joint of the hand of the pat... | 05/01/2012 |
| 8163493 | Targets for use in diagnosis, prognosis and therapy of cancer Provided herein are targets that can be used for the diagnosis, prognosis and therapy of a variety of cancers. ... | 04/24/2012 |
| 8155744 | Neuromodulatory methods for treating pulmonary disorders A method for treating a pulmonary disorder in a subject includes inserting a therapy delivery device into a vessel of the subject, advancing the therapy delivery device to a point adjacent an intraluminal target site of the autonomic nervous system, and activating t... | 04/10/2012 |
| 8155735 | Prediction and prevention of postoperative atrial fibrillation in cardiac surgery patients Systems and methods are provided for predicting the onset of postoperative atrial fibrillation (AF) from electrocardiogram (ECG) data representing a patient. A signal processing component determines parameters representing the activity of the heart of the patient fr... | 04/10/2012 |
| 8147481 | Vascular guidewire control apparatus A controller for use with a guidewire, such as a vascular guidewire, provides a mechanism for gripping and applying a torque to the guidewire without the need to thread the guidewire axially through the controller and at a location close to a point of access of the ... | 04/03/2012 |
| 8143224 | Oxidant resistant apolipoprotein A-1 and mimetic peptides A purified polypeptide includes an ApoA1 mimetic or fragment thereof that are resistant to oxidation. ... | 03/27/2012 |
| 8140170 | Method and apparatus for renal neuromodulation An apparatus for renal neuromodulation includes an expandable support member having a main body portion for engaging a wall of a blood vessel proximate a renal vasculature and at least one electrode connected with the main body portion. The at least one electrode is... | 03/20/2012 |
| 8138265 | Hydroxyphenyl cross-linked macromolecular network and applications thereof A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or syn... | 03/20/2012 |
| 8137991 | Methods of reducing angiogenesis of age-related macular degeneration (AMD) or choroidal neovascularization by an anti-carboxyetheylpyrrole (CFP) antibody The present invention pertains to methods of inhibiting angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of oxidative peptide modifi... | 03/20/2012 |
| 8137688 | Hydroxyphenyl cross-linked macromolecular network and applications thereof A synthetic nucleus pulposus is provided that is useful in treatment of degenerative disc disease, augmentation of a degenerate disc, and alleviation of back pain. In an embodiment the synthetic nucleus pulposus comprises hyaluronan macromolecules that have been cro... | 03/20/2012 |
| 8133866 | Method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury This invention provides for a method for inhibiting new tissue growth in blood vessels in a subject, wherein the subject experienced blood vessel injury, which comprises administering to the subject a pharmaceutically effective amount of an inhibitor of receptor for... | 03/13/2012 |
| 8112154 | Systems and methods for neuromodulation using pre-recorded waveforms Methods for neuromodulation using waveform signals. In certain embodiments, an input waveform is obtained from a signal source site in a source subject and an output waveform is applied to a target site in a target subject. The source subject is a human or animal an... | 02/07/2012 |
| 8105375 | Method for implanting a cardiovascular valve A method is provided for implanting a valve having at least one valve leaflet within the cardiovascular system of a subject. One step of the method includes preparing a substantially dehydrated bioprosthetic valve and then providing an expandable support member havi... | 01/31/2012 |
| 8100950 | Oblique lumbar interbody fusion A method fuses an inferior vertebra and a superior vertebra together. The method includes the steps of: extending a screw obliquely, both anteriorly and superiorly, through the inferior vertebra; and further extending the screw across an interbody space and into the... | 01/24/2012 |
| 8092495 | Spinal platform and method for delivering a therapeutic agent to a spinal cord target A spinal platform for delivering a therapeutic agent to a spinal cord target includes a brace member for attachment to a plurality of bony structures surrounding at least a portion of the spinal cord target, a carriage member operatively coupled to and movable along... | 01/10/2012 |
| 8088084 | Method and apparatus for repair of intervertebral discs A method of repairing an intervertebral disc of a patient's body includes identifying a target area of the intervertebral disc. An ultrasound generator is placed proximate the target area and outside the patient's body. An area temperature at the target area is moni... | 01/03/2012 |
| 8082033 | System and method for providing a waveform for stimulating biological tissue An implantable programmable stimulator system includes memory that stores waveform data for at least one waveform. A playback system provides at least one output waveform based on the waveform data. ... | 12/20/2011 |
| 8080260 | Molecular enhancement of extracellular matrix and methods of use A composition comprising a human- or animal-derived extracellular matrix and a macromolecular network which is prepared ex vivo is provided that is useful in the repair of a tissue injury, particularly in repair of tears or gaps between a tendon and a bone, such as ... | 12/20/2011 |
| 8080252 | Compounds and methods of modulating angiogenesis A method of modulating angiogenesis in a tissue comprises administering to the tissue a therapeutically effective amount of an agent that modulates complex formation of αvβ3 integrin and VEGFR2. ... | 12/20/2011 |
| 8068670 | Image analysis of biological objects Systems and methods are described for performing image analysis. A computer-implemented method for analyzing images may include quantitatively analyzing image data to identify image objects relative to a background portion of the image according to predefined object... | 11/29/2011 |
| 8066748 | Apparatus and method for affixing body structures An apparatus for affixing a plurality of body structures together in a flexible manner includes a first articulated fastener having substantially rigid proximal and distal portions, longitudinally separated by a first flexible articulating portion. The first articul... | 11/29/2011 |
| 8052640 | Method and apparatus for increasing blood flow through an obstructed blood vessel A method of increasing blood flow through an obstructed blood vessel includes providing an expandable member substantially made of a mesh having a plurality of interstices. The expandable member is inserted into the blood vessel, positioned within the blood vessel w... | 11/08/2011 |
| 8048411 | Co-transplantation of hepatic stellate cells and islet cells A method of inhibiting graft rejection includes isolating Hepatic Stellate Cells from a mammal liver, activating the isolated Hepatic Stellate Cells, and administering a combination of Hepatic Stellate cells and a graft to a mammal. ... | 11/01/2011 |
| 8048233 | Methods and devices to clear obstructions from medical tubes A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of... | 11/01/2011 |
| 8046075 | Electrical stimulation of the sympathetic nerve chain The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological c... | 10/25/2011 |
| 8043354 | Thoracic deployment device and stent graft A stent graft introducer for intraluminal deployment of a stent graft (26), the introducer comprising a stent graft release mechanism (6) to allow partial release of the stent graft (26) when carried on the introducer, whereby control of the ste... | 10/25/2011 |
| 8031211 | Techniques for 3-D elastic spatial registration of multiple modes of measuring a body Techniques for registration of multiple measurement modes of a body include receiving first and second data from different modes. Each includes measured values with coordinate values. For two mechanically aligned modes, any non-rigid registration is performed. For s... | 10/04/2011 |
| 8030063 | Systems and methods for vitrifying tissue An apparatus for vitrifying a biological specimen includes a cap member, a tubular plunger, and a specimen chamber. The cap member includes a stem portion integrally formed with a receiving portion. The receiving portion has a disc-like shape and includes an outer s... | 10/04/2011 |
| 8021350 | Hydroxyphenyl cross-linked macromolecular network and applications thereof A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or syn... | 09/20/2011 |
| 8020275 | Method for compressing intraluminal prostheses A method for compressing an intraluminal prosthesis provides a mesh tube having first and second longitudinally spaced tube ends and a hollow tube bore located therebetween. The intraluminal prosthesis is completely inserted into the hollow tube bore. The tube is st... | 09/20/2011 |
| 8019404 | Apparatus and method for targeting a body tissue An apparatus for targeting a desired target site on a body tissue that separates a first body cavity from a second body cavity of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the first body cavity. A... | 09/13/2011 |
| 8014984 | Method and apparatus for preparing for a surgical procedure A method of preparing for a surgical procedure includes creating a three-dimensional bone model of a subject bone of a patient. At least a portion of the bone model is compared to at least one three-dimensional reference anatomic model. At least one structural diffe... | 09/06/2011 |
| 7998123 | Intrajugular catheter A catheter for insertion into a vascular system of a patient and for directing fluid flow includes a catheter body having a longitudinal axis and longitudinally spaced proximal and distal catheter ends with an intermediate catheter portion defined therebetween. An i... | 08/16/2011 |
| 7993639 | Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases In one embodiment, a therapeutic composition containing a pentavalent antimonial is provided. The pentavalent antimonial can be sodium stibogluconate, levamisole, ketoconazole, and pentamidine and biological equivalents of said compounds. Additionally, pentavalent a... | 08/09/2011 |
| 7978916 | System and method for identifying a vascular border A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular u... | 07/12/2011 |
| 7955362 | Apparatus and method for body tissue fixation A body tissue fixation apparatus includes a plate having oppositely disposed outer and tissue-contacting surfaces, and at least one fixation hole extending between the outer and tissue-contacting surfaces along a longitudinal axis. The fixation hole is defined in pa... | 06/07/2011 |
| 7951243 | Methods and devices to clear obstructions from medical tubes A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a shuttle member that is magnetically coupled to a guide wire within a guide tube, through the guide-tube wall, so that translation... | 05/31/2011 |
