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| Number | Title | Issue Date |
| 7911622 | System and method for using slow light in optical sensors An optical sensor includes at least one optical coupler and an optical waveguide in optical communication with the at least one optical coupler. The optical waveguide is configured to receive a first optical signal from the at least one optical coupler. The first op... | 03/22/2011 |
| 7881565 | Device and method using asymmetric optical resonances An optical resonator includes a reflective element and an optical fiber. The optical fiber is positioned relative to the reflective element such that light emitted from the optical fiber is reflected by the reflective element. The optical resonator has an optical re... | 02/01/2011 |
| 7851587 | Peptides derived from the C2 domain of epsilon PKC Peptides derived from the C2 regions of εPKC and methods of use, thereof, are described. These peptides modulate the activity of εPKC in an animal model of acute ischemic heart disease. ... | 12/14/2010 |
| 7835559 | Method and apparatus for quantitative and comparative analysis of image intensities in radiographs A system for determining image intensity of a radiograph includes an illuminator for providing lighting to the radiograph, an image reference standard having a predetermined color, a digital imaging device for obtaining a digital image of the radiograph and the imag... | 11/16/2010 |
| 7833984 | Peptide inhibitors of protein kinase C PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations... | 11/16/2010 |
| 7833719 | Apparatus and methods for parallel processing of micro-volume liquid reactions Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array o... | 11/16/2010 |
| 7823058 | Methods and apparatus for interactive point-of-view authoring of digital video content The present invention provides electronic methods and apparatus for interactively authoring, sharing and analyzing digital video content. Methods for authoring include displaying visual data, defining each traversal as a time-based sequence of frames and annotating ... | 10/26/2010 |
| 7803775 | Protein kinase C peptides for use in withdrawal A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ε and/or γ isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent... | 09/28/2010 |
| 7778386 | Methods for analytic reconstruction for mult-source inverse geometry CT Disclosed are embodiments of methods for reconstructing x-ray projection data (e.g., one or more sinograms) acquired using a multi-source, inverse-geometry computed tomography (“IGCT”) scanner. One embodiment of a first method processes an IGCT sinogram by rebin... | 08/17/2010 |
| 7777191 | Method and system of adaptive exposure for a camera A method and/or device of adaptively controlling an exposure duration for a camera. A determination is made as to whether motion is present. If it is determined that motion is present, exposure duration for one or more images is automatically decreased. If it is det... | 08/17/2010 |
| 7746480 | Apparatus for characterizing fiber Bragg gratings An apparatus characterizes at least one fiber Bragg grating. The apparatus includes a laser pulse source, an optical spectrum analyzer, and multiple optical paths. A first optical path includes a pulse stretcher and an attenuator. A second optical path optically cou... | 06/29/2010 |
| 7745412 | Isozyme-specific antagonists of protein kinase C A method of changing or otherwise converting the biological activity of a PKC peptide agonist to a peptide antagonist is described. The method involves substituting one or more amino acid residues so as to effect a change in charge in the peptide and/or to otherwise... | 06/29/2010 |
| 7738109 | Fiber optic sensor using a Bragg fiber An optical sensor includes a directional coupler comprising at least a first port, a second port, and a third port. The first port is in optical communication with the second port and with the third port such that a first optical signal received by the first port is... | 06/15/2010 |
| 7700323 | Method for detecting and amplifying target DNA The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids,... | 04/20/2010 |
| 7684664 | Microresonator optical switch An optical switch includes a microresonator comprising a plurality of nanoparticles. The microresonator is configured to receive signal light having a signal wavelength and to receive a pump pulse having a pump wavelength. At least a portion of the microresonator is... | 03/23/2010 |
| 7670584 | Inorganic metal chalcogen cluster precursors and methods for forming colloidal metal chalcogenide nanoparticles using the same Methods for forming colloidal metal chalcogenide nanoparticles generally include forming soluble inorganic metal chalcogen cluster precursors, which are then mixed with a surfactant and heated to form the colloidal metal chalcogenide nanoparticles. The soluble inorg... | 03/02/2010 |
| 7643952 | Optical image processing using minimum phase functions A method processes an optical image. The method includes providing a measured magnitude of the Fourier transform of a two-dimensional complex transmission function. The method further includes providing an estimated phase term of the Fourier transform of the two-dim... | 01/05/2010 |
| 7630604 | Dipole induced transparency drop-filter cavity-waveguide system A normally opaque waveguide interacting with a drop-filter cavity can be switched to a transparent state when the drop filter is also coupled to a dipole. This dipole induced transparency may be obtained even when the vacuum Rabi frequency of the dipole is much less... | 12/08/2009 |
| 7598275 | Nicotine in therapeutic angiogenesis and vasculogenesis Methods are provided for induction of angiogenesis by administration of nicotine or other nicotine receptor agonist. Induction of angiogenesis by the methods of the invention can be used in therapeutic angiogenesis in, for example, treatment of ischemic syndromes su... | 10/06/2009 |
| 7585834 | Transporters comprising spaced arginine moieties The present invention provides compositions and methods for enhancing transport of biologically active compounds across biological membranes and across and into animal epithelial or endothelial tissues. The composition includes a biologically active agent and a tran... | 09/08/2009 |
| 7563772 | Methods of increasing cerebral blood flow Methods of increasing blood flow in a mammalian brain blood vessel characterized by, or otherwise experiencing, decreased blood flow due to an ischemic or other hypoxic event, vasoconstriction or vasospasm following hemorrhagic stroke; due to chronic high blood pres... | 07/21/2009 |
| 7563430 | Inorganic metal chalcogen cluster precursors and methods for forming colloidal metal chalcogenide nanoparticles using the same Methods for forming colloidal metal chalcogenide nanoparticles generally include forming soluble inorganic metal chalcogen cluster precursors, which are then mixed with a surfactant and heated to form the colloidal metal chalcogenide nanoparticles. The soluble inorg... | 07/21/2009 |
| 7544654 | ψεRACK peptide composition and method for protection against tissue damage due to ischemia A method of reducing damage to cells and tissue caused by an ischemic or hypoxic event is disclosed. The method includes administering to the cell or tissue, either in vivo or ex vivo, ψεRACK peptide. The peptide can be administered before, during or after the isc... | 06/09/2009 |
| 7530952 | Capacitive ultrasonic transducers with isolation posts A capacitive ultrasonic transducer is described which include one or more cells including a cavity defined by a membrane electrode supported spaced from a support electrode by insulating walls with a patterned isolation layer having isolation posts or areas located ... | 05/12/2009 |
| 7507711 | Peptide inhibitors of protein kinase C PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations... | 03/24/2009 |
| 7505881 | Method and apparatus for modeling the modal properties of optical waveguides A method and apparatus models one or more electromagnetic field modes of a waveguide. The method includes sampling a two-dimensional cross-section of the waveguide. The method further includes calculating a first matrix having a plurality of elements and having a fi... | 03/17/2009 |
| 7493227 | Method for determining the complex scattering function of an optical coherence tomography sample A method determines the complex scattering function of a portion of a sample under analysis. The method includes providing a magnitude spectrum of a complex spatial Fourier transform of a complex intermediate function. The complex intermediate function is dependent ... | 02/17/2009 |
| 7480034 | Apparatus for characterizing fiber bragg gratings An apparatus characterizes at least one fiber Bragg grating. The apparatus includes a laser pulse source, an optical spectrum analyzer, and multiple optical paths. A first optical path includes a pulse stretcher and an attenuator. A second optical path optically cou... | 01/20/2009 |
| 7459424 | Peptide inhibitors of protein kinase C γ for pain management Peptide sequences derived from the V5 domain of isozymes of protein kinase C for use in pain management are described. Also described are compositions comprising the peptides for treating pain and/or inducing analgesia. Methods of pain treatment and methods of ident... | 12/02/2008 |
| 7451638 | Harmonic cantilevers and imaging methods for atomic force microscopy A harmonic cantilever for use in an atomic force microscope includes a cantilever arm and a probe tip. The cantilever arm has a shape selected to tune the fundamental resonance frequency or a resonance frequency of a selected higher order mode so that the fundamenta... | 11/18/2008 |
| 7430345 | Polarization controller using a hollow-core photonic-bandgap fiber A polarization controller is provided. The polarization controller includes a hollow-core photonic-bandgap fiber, wherein at least a portion of the hollow-core photonic-bandgap fiber has a longitudinal axis and is twisted about the longitudinal axis. ... | 09/30/2008 |
| 7404314 | Atomic force microscope using a torsional harmonic cantilever An atomic force microscope based apparatus for examining a sample includes a cantilever having a cantilever arm and a probe tip where the probe tip is offset laterally from a longitudinal axis of torsion of the cantilever arm, an oscillator that drives the cantileve... | 07/29/2008 |
| 7385683 | Method of characterizing fiber Bragg gratings using iterative processing A method determines a complex reflection impulse response of a fiber Bragg grating. The method includes providing a measured amplitude of a complex reflection spectrum of the fiber Bragg grating. The method further includes providing an estimated phase term of the c... | 06/10/2008 |
| 7369953 | Femtosecond spectroscopy using minimum phase functions A method determining a transient response includes providing a measured magnitude of the Fourier transform of a complex electric field temporal profile of a pulse sequence comprising a probe pulse and a dummy pulse, wherein the probe pulse is indicative of the trans... | 05/06/2008 |
| 7363165 | Significance analysis of microarrays Microarrays can measure the expression of thousands of genes and thus identify changes in expression between different biological states. Methods are needed to determine the significance of these changes, while accounting for the enormous number of genes. We describ... | 04/22/2008 |
| 7357915 | Method of imaging cell death in vivo A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. ... | 04/15/2008 |
| 7313493 | Method of retrieving phase and magnitude of weak ultra-short optical pulses using a stronger unknown pulse A method determines a complex electric field temporal profile of an optical pulse. The method includes providing a measured magnitude of the Fourier transform of a complex electric field temporal profile of a pulse sequence comprising the optical pulse and a dummy p... | 12/25/2007 |
| 7302833 | Torsional harmonic cantilevers for detection of high frequency force components in atomic force microscopy A method for measuring high frequency force of interaction between a tip of a cantilever and a sample includes providing a cantilever having a cantilever arm and a probe tip formed on a free end of the cantilever arm where the cantilever arm has a first shape and an... | 12/04/2007 |
| 7235526 | Protein kinase C peptides for use in withdrawal A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ε and/or γ isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent... | 06/26/2007 |
| 7231839 | Electroosmotic micropumps with applications to fluid dispensing and field sampling Apparatus and methods according to the present invention preferably utilize electroosmotic pumps in fluid handling and field sampling applications. The electroosmotic pumps used in these applications are capable of generating high pressure and flow without moving me... | 06/19/2007 |