Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7842478 | DNA encoding mammalian phosphodiesterases The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding reco... | 11/30/2010 |
| 7122363 | DNA encoding mammalian phosphodiesterases The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding reco... | 10/17/2006 |
| 6867020 | Method of making glycoprotein exhibiting erythropoiesis regulating and glycoprotein produced by this method The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines. ... | 03/15/2005 |
| 6642040 | Human cGMP-stimulated cyclic nucleotide phosphodiesterase The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+ /calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corres... | 11/04/2003 |
| 6304870 | Method and apparatus of automatically generating a procedure for extracting information from textual information sources A procedure is disclosed for automatically constructing wrappers for performing information-extraction from sites such as Internet resources that display relevant information, interspersed with extraneous text fragments, such as HTML formatting commands o... | 10/16/2001 |
| 6025176 | Cloning and expression of human islet glutamic acid decarboxylase autoantigen Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polype... | 02/15/2000 |
| 6015677 | Assay methods using DNA encoding mammalian phosphodiesterases The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+ /calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corres... | 01/18/2000 |
| 5995959 | Method and system for network information access This invention provides methods to locate and plan the retrieval of data from networked information sources in response to a user query. The methods utilize descriptions of the information sources, the information domain of the sources, and of the query. ... | 11/30/1999 |
| 5976466 | Multiple-probe diagnostic sensor There is disclosed a diagnostic sensor device comprising a plurality of sensor probes, a detection device, and a computer for analyzing the signals generated from each sensor probe by multivariate statistical analysis. The plurality of sensor probes compr... | 11/02/1999 |
| 5869609 | G protein coupled glutamate receptors Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G... | 02/09/1999 |
| 5830133 | Characterizing biological matter in a dynamic condition using near infrared spectroscopy A method for predicting a property of biological matter, such as biological fluid, containing water, in a dynamic condition where the biological fluid may be approximated to contain two compartments where one compartment has a proportionally larger or sma... | 11/03/1998 |
| 5792620 | Cloning and expression of human islet glutamic acid decarboxylase autoantigen Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polype... | 08/11/1998 |
| 5789553 | Antibodies specifically immunoreactive with human brain Ca2+ /calmodulin cyclic nucleotide phosphodiesterase The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+ /calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corres... | 08/04/1998 |
| 5747267 | Method for identifying a G protein coupled glutamate receptor agonist and antagonist Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G... | 05/05/1998 |
| 5721107 | Antibodies to G protein coupled glutamate receptors Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G... | 02/24/1998 |
| 5690635 | Prosthesis template for use in a robot-aided system for surgery A prosthesis template for aiding in the determination of a desired position of a prosthesis relative to a bone, the prosthesis having an exterior surface that simulates the exterior surface of the bone and an interior surface comprised of one or more cont... | 11/25/1997 |
| 5663314 | Human signal transduction MAPK kinase An isolated nucleic acid molecule which hybridizes under stringent conditions with the nucleic acid shown in SEQ ID NO:32 or its complement or the nucleic acid shown in SEQ ID NO:34 or its complement, and which encodes mitogen activated protein kinase kin... | 09/02/1997 |
| 5434084 | Flow optrode having separate reaction and detection chambers There is disclosed a device capable of continuously measuring the presence and concentration of an analyte or analytes and a method for using said device in a liquid and/or a gas phase reaction volume. The inventive device comprises a sensor probe, a rese... | 07/18/1995 |
| 5385831 | Method for producing a mammalian G protein coupled glutamate receptor Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G... | 01/31/1995 |
| 5342369 | System for repair of bankart lesions An elongated drill and suture guide is inserted through a posterior portal during arthroscopic surgery to repair a Bankart lesion of a human shoulder. The drill and suture guide has a linear longitudinal bore for a drill pin effective to bore through the ... | 08/30/1994 |
| 5302529 | Plasmid coding for human protein C Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C are disclosed. Recombinant plasmids and bacteriophage transfer vectors incorporating these sequences are also disclosed.... | 04/12/1994 |
| 5300630 | Oncofetal fibronectin epitope An onco-developmentally regulated -N-acetylgalactosaminyltransferase isolated as a component of a particulate membrane fraction separated from cell and tissue homogenates and having the following characteristics: (a) Activity in Various Cells and Tissue... | 04/05/1994 |
| 5223545 | Polyethylene terephthalate foams with integral crystalline skins Polyethylene terephthalate composite structures having integral crystalline skins on a foam of polyethylene terephthalate are described. The structures exhibit enhanced physical properties compared to polyethylene terephthalate foams. The structures are p... | 06/29/1993 |
| 5171267 | Surface-modified self-passivating intraocular lenses The invention relates to intraocular lenses coated with C12 -C36 alkyl groups that render the surface of the intraocular lens less prone to causing inflammation after implantation of the intraocular lens. The alkyl groups may be coat... | 12/15/1992 |
| 5166615 | System for detecting nuclear magnetic resonance signals from small samples Apparatus and methods for detecting NMR signals from small samples using mechanical oscillators. In one embodiment, the sample is affixed to the mechanical oscillator, and immersed in a magnetic field. Magnetic resonance is detected by monitoring the mech... | 11/24/1992 |
| 5154717 | Robot-aided system for surgery A system and method for positioning a tool relative to a patient's bone to facilitate the performance of a surgical bone alteration task. The system comprises a bone immobilization device for supporting the bone in a fixed position with respect to a refer... | 10/13/1992 |
| 5114580 | Combined hemofiltration and hemodialysis system A hemodialysis system has a blood circuit and a hemofiltrate circuit interconnected at a hemofilter and an air collection chamber. If an infusion of sterile fluid to the returning blood is needed during the dialysis treatment, filtrate in the filtrate cir... | 05/19/1992 |
| 5096539 | Cell wall loading of never-dried pulp fibers There is also disclosed a process for the production of filled paper using never-dried pulp fibers and filler comprising an insoluble precipitate that is precipitated in situ within the cell wall of the fibers. The process first immerses the never-dried p... | 03/17/1992 |
| 5088498 | Ultrasonic plethysmograph Quadrature phase signals (I and Q) from a pulsed Doppler medical instrument are analyzed to detect phase changes of consecutive echoes from tissue at a depth of interest. Such phase changes are analyzed to determine tissue displacement. Relative displacem... | 02/18/1992 |
| 5073609 | DNA sequence coding for protein C Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C are disclosed. Recombinant plasmids and bacteriophage transfer vectors incorporating these sequences are also disclosed.... | 12/17/1991 |
| 5021452 | Process for enhancing wound healing There is disclosed a process for improving wound healing, comprising administering ascorbate or derivatives thereof to a wound site at a concentration of at least 20 μmol/L and irradiating the wound site with a low-power laser at a wave length of about 6... | 06/04/1991 |
| 5008186 | Detection of unique chlamydia strain associated with acute respiratory disease Methods for detecting a unique strain of chlamydia associated with acute respiratory disease are disclosed. These methods utilize monoclonal antibody directed against an antigenic determinant of the TWAR strain of chlamydia. Also disclosed is a method for... | 04/16/1991 |
| 5002794 | Method of controlling the chemical structure of polymeric films by plasma A method of controlling the chemical structure of thin films formed by plasma deposition and films produced by these methods, is disclosed. An important aspect of the method involves controlling the temperature of the substrate and the reactor so as to cr... | 03/26/1991 |
| 4966841 | Enhanced vector production and expression of recombinant DNA products A 2,356 base pair fragment isolated from the human X chromosome, designated as Xrep, has been found to exert a positive effect on plasmid replication in both prokaryotic and eukaryotic cells. The Xrep, in addition, has been found to increase transcription... | 10/30/1990 |
| 4937324 | Chromatographic purification of human proteins having anticoagulant and anti-inflammatory activity Proteins having therapeutic potential as both anticoagulants and as anti-inflammatory agents are disclosed. The present invention also discloses the use of lipocortins in reducing blood coagulation in warm-blooded animals.... | 06/26/1990 |
| 4919659 | Radio frequency plasma deposited polymers that enhance cell growth A method for enhancing bio-material capability for use as a supporting surface for cell culture is disclosed. The method requires exposure of the bio-material to a plasma polymerizable polymer gas, which includes oxygen-containing organic molecules. The m... | 04/24/1990 |
| 4898878 | Antioxidant thiohistidine compounds Therapeutic antioxidant compounds, useful for relieving the pathogenesis of oxidative stress, of formula ##STR1## wherein substituents R1, R2, R3, and R4 are individually selected from among hydrogen, methy... | 02/06/1990 |
| 4816131 | pH/PCO2 PO2 electrode A double and triple barrel electrode for the simultaneous measurement of pH and PCO2 ; and pH, PCO2 and P02 employing a membrane in conjunction with a pH fluid and fluids responsive to CO2 and O2. The... | 03/28/1989 |
| 4783987 | System for sustaining and monitoring the oscillation of piezoelectric elements exposed to energy-absorptive media The disclosed system includes a piezoelectric crystal exposed to an energy-absorptive medium of interest. A crystal oscillation circuit is included for sustaining oscillation of the crystal in contact with the fluid. To accomplish this, the circuit includ... | 11/15/1988 |
| 4770185 | Method and apparatus for endoscopic blood flow detection by the use of ultrasonic energy A system for endoscopic detection of blood flow is disclosed. A catheter is sized to pass through the biopsy channel of an endoscope and includes an elongated catheter tube of flexible material and an ultrasonic probe carried by the catheter tube adjacent... | 09/13/1988 |