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| Number | Title | Issue Date |
| 5841039 | Apparatus and method for integrated sampling from closed and open sample containers Integrated sampler apparatus and method are provided and include a sample liquid container support component which is operable to support both closed and open sample liquid containers thereon on a random basis. Sample liquids from the open sample liquid c... | 11/24/1998 |
| 5728954 | Apparatus and method for integrated sampling from closed and open sample containers Integrated sampler apparatus and method are provided and include a sample liquid container support component which is operable to support both closed and open sample liquid containers thereon on a random basis. Sample liquids from the open sample liquid c... | 03/17/1998 |
| 5201232 | Integrated sampler for closed and open sample containers Integrated sampler apparatus and method are provided and include a sample liquid container support component which is operable to support both closed and open sample liquid containers thereon on a random basis. Sample liquids from the open sample liquid c... | 04/13/1993 |
| 5192504 | Flushable low carryover container Minimum carryover container for the successive containment of discrete liquids as are successively introduced thereinto, and minimum carryover discrete liquid analysis system utilizing the container, are disclosed; and operate through use of container mat... | 03/09/1993 |
| 5174872 | Metal-free buffer for ion selective electrode-based assays A heavy metal-free composition and its method of use in an ion selective electrode-based assay are disclosed. The heavy metal-free composition includes a borate compound and an alkalinity adjusting compound, and is used to dilute a test sample; buffer the... | 12/29/1992 |
| 5149658 | Method for the separation and/or formation of immiscible liquid streams Apparatus and method are provided for the substantial separation on a continuous flow basis of immiscible liquids flowing as a common stream, with one of the liquids substantially encapsulating another of the liquids, in a flow conduit. The conduit compri... | 09/22/1992 |
| 5122453 | Method for discriminating surface stained lymphocytes A flow cytometry method for reproducibly detecting and counting a lymphocyte population of interest in a leukocyte suspension or whole blood sample in which the red cells are subsequently lysed. The suspension (or sample) is combined with a reagent compri... | 06/16/1992 |
| 5106758 | Analytical test device and the use thereof The analytical device includes a base adapted to support a porous member having dispersed throughout at least one analyte responsive substance which undergoes a detectable response to the presence and concentration of the analyte in the test sample. A cov... | 04/21/1992 |
| 5075556 | Acridine orange derivatives and their use in the quantitation of reticulocytes in whole blood Quaternized derivatives of acridine orange and reagents incorporating such derivatives and their use in quantitatively determining reticulocyte levels in whole blood specimen by fluorescence flow cytometry techniques are disclosed. The quaternized derivat... | 12/24/1991 |
| 5075079 | Slide analysis system The slide analysis system includes a slide holding module spaced from an incubator module. A slide transfer device or pick and place mechanism withdraws slides from the slide holding module and inserts them into the incubator module. A metering device dep... | 12/24/1991 |
| 5073501 | Method for determining the concentration of cations in a sample The invention is reagents and procedures for determining an amount of cations present in a sample, the reagent including one or more chromogenic cryptand compounds of formula I ##STR1## wherein k and j, either same or different, are equal to 1 to abo... | 12/17/1991 |
| 5068180 | Substrates for ଲ-galactosidase A substrate for ଲ-galactosidase having the general formula ##STR1## wherein X is halogen; Y is halogen, lower alkyl or hydrogen; W is lower alkyl or hydrogen; and Z is nitro.... | 11/26/1991 |
| 5064955 | Large scale, non-chromatographic purification of chromogenic cryptahemispherands (1.1) and (2.1) A process is disclosed for the non-chromatographic purification of chromogenic cryptahemispherands of the following general formula (II) which are capable of selective binding of sodium ion in aqueous solution: ##STR1## wherein: R, same or different,... | 11/12/1991 |
| 5064542 | Method for filtering a whole blood sample using an in-line fluid filter for an automated analyzer A method for filtering a whole blood sample using a filter element constructed and arranged to block the passage of fibrous and particulate matter which may be present in a liquid sample, such as a whole blood sample, while allowing the blood cells to pas... | 11/12/1991 |
| 5061450 | Isolation fluid control device and water cup An isolation fluid control device and water cup for use in an automated, random-access, isolation fluid-based, analytical instrument. The cup, in operation, contains two immiscible liquids. The cup is provided with inlets and outlets, and additionally com... | 10/29/1991 |
| 5045475 | Reagent for determining cations The invention is reagents and procedures for determining an amount of cations present in a sample, the reagent including one or more chromogenic cryptand compounds of formula I ##STR1## wherein k and j, either same or different, are equal to 1 to abo... | 09/03/1991 |
| 5045472 | Reagent mixture and composition for treating red blood cells to effect sphering A composition is disclosed of blood serum sample preparation for improved, more accurate and precise, electrooptical method for measuring erythrocyte volumes, individually and as an average.... | 09/03/1991 |
| 5045473 | Apparatus and method for the separation and/or formation of immicible liquid streams Apparatus and method are provided for the substantial separation on a continuous flow basis of immisicible liquids flowing as a common stream, with one of said liquids substantially encapsulating another of said liquids, in a flow conduit. The conduit com... | 09/03/1991 |
| 5019999 | Immunoanalysis method for discriminating between antigen excess and antibody excess conditions A method of immunoassay for analyzing a bodily fluid for the presence of an analyte relies on observing substantially the entire course of a precipitin reaction from initiation to substantial completion of the precipitation, defining a mathematical functi... | 05/28/1991 |
| 5011924 | Chromogenic cryptahemispherands and their preparation The present invention resides in the discovery of a new class of compounds defined herein as "chromogenic cryptahemispherands" useful for the measurement of ions, in particular, ions in aqueous solution, which have the structure ##STR1## wherein... | 04/30/1991 |
| 4997768 | Anti-foaming method for liquid dispensing Liquid dispensing method is provided, and comprises the steps of periodically rotating a liquid dispenser package to supply a liquid from a liquid supply chamber to a liquid reservoir by flowing the liquid under the influence of centrifugal force through ... | 03/05/1991 |
| 4994395 | Chromogenic cryptand reagents and methods for determining cation concentrations in test samples containing interfering cations The invention is reagents and procedures for determining an amount of cations present in a sample, the reagent comprising (a) one or more chromogenic cryptand compounds of formula I ##STR1## wherein k and j, either same or different, are equal to 1 to abo... | 02/19/1991 |
| 4992381 | Method of detecting electrolytes in an aqueous test sample using chromogenic hemispherands and test device therefor The present invention resides in the discovery of a new class of compounds defined herein as "chromogenic hemispherands" useful for the measurement of ions, in particular, ions in aqueous solution, methods of using the chromogenic hemispherands and test d... | 02/12/1991 |
| 4989978 | Method and apparatus for determining the count per unit volume of particles A method and apparatus for accurately determining the count per unit volume of particles, such as red blood cells, suspended in a fluid containing at least one undesirable interference particle, such as air bubbles. A predetermined volume of fluid contain... | 02/05/1991 |
| 4978624 | Reagent for the determination of a differential white blood cell count This invention relates to a method for the rapid determination of a differential white blood cell count in a sample, which method comprises: (a) preparing a reagent solution comprising formaldehyde or paraformaldehyde; a surfactant; a sugar or sugar alcohol; and a ... | 12/18/1990 |
| 4971912 | Apparatus and method for the separation of immiscible liquids Apparatus and method for the separation of immiscible liquids are provided, and comprise the use of separator means having a surface which is preferentially "wettable" by one of the liquids to the substantial exclusion of another of the liquids. In use, t... | 11/20/1990 |
| 4944924 | Test tube holder The test tube holder includes an elongated tubular member which supports a pivot member thereby rendering the tubular member and pivot member relatively pivotable with respect to each other. Latch members provided on the tubular member and pivot member ar... | 07/31/1990 |
| 4900818 | Large scale synthesis of twelve member diazamonocyclic compounds A process is disclosed for synthesizing large quantities of a compound of formula I ##STR1## wherein a solution of a compound of formula II ##STR2## is mixed with a solution of a compound of formula III ##STR3## under suitable process ... | 02/13/1990 |
| 4865993 | Minimum carryover container, and analysis system incorporating the same Minimum carryover container for the successive containment of discrete liquids as are successively introduced thereinto, and minimum carryover discrete liquid analysis system utilizing the container, are disclosed and operate through use of container mate... | 09/12/1989 |
| 4863066 | System for dispensing precisely metered quantities of a fluid and method of utilizing the system A fluid delivery system for dispensing precisely metered quantities of a fluid, and more particularly, a fluid delivery system incorporating a diaphragm pump for effectuation of the precise control over the dispensing of a metered quantity of the fluid th... | 09/05/1989 |
| 4861553 | Automatic sampling system The automatic sampling system includes a test apparatus for testing specific characteristics of a fluid withdrawn from a closed test tube. Stoppered test tubes are continuously and automatically delivered to the test apparatus by a conveyor system that in... | 08/29/1989 |
| 4859606 | Method for detecting cations in a test sample utilizing chromogenic cryptahemispherands The present invention resides in the discovery of a class of compounds defined herein as "chromogenic cryptahemispherands" useful for the measurement of ions, in particular, ions in aqueous solution, which have the structure ##STR1## wherein: R,... | 08/22/1989 |
| 4857247 | Method for drawing thermoplastic tubing The specification discloses a new method and apparatus for treating extruded TEFLON (fluoropolymer) tubing to significantly improve its dimensional and optical characteristics. Diameter tolerance is &#b1;0.0002, concentricity rises to 95%, and optical cla... | 08/15/1989 |
| 4853338 | Cyanide-free hemoglobin reagent A method and reagent useful therein are cyanide-free and capable of providing a rapid indication, e.g., less than 30 seconds, of total hemoglobin in a blood sample, so as to fine particular application in automated hematological instrumentation. The novel... | 08/01/1989 |
| 4853336 | Single channel continuous flow system A continuous flow system is disclosed in which successive liquid segments are established containing different related components of a fluid package, such as an analysis mixture, separated by at least one immiscible segment, passed along a first section o... | 08/01/1989 |
| 4845212 | Process for the preparation of chromogenic cryptahemispherands The invention relates to a process in which a variety of cryptahemispherands bearing a chromogenic group attached to the partially preorganized moiety may be synthesized. The procedure of the present invention allows preparation of preferred chromogenic c... | 07/04/1989 |
| 4839276 | Interference - resistant liposome specific binding assay A method and reagent composition provide for the removal or blocking of serum interferences in liposome immunoassays. A carrier or liposome exhibiting at least one domain of phosphoryl ester groupings different from those of the marker liposome is introdu... | 06/13/1989 |
| 4816411 | Method for eliminating turbidity in a biological fluid and reagent therefor A method for eliminating turbidity in a biological fluid by combining said fluid with a surfactant and an enzyme is disclosed as well as a diagnostic reagent formulation for that purpose.... | 03/28/1989 |
| 4811611 | Apparatus and method for pressure equalization in closed tube sampler Sampler apparatus and method are provided and include both closed and open tube samplers, and selector valve operable to select therebetween for sample supply to automated sample analysis apparatus. A shear valve divides the samples into separate sample q... | 03/14/1989 |
| 4810351 | Carbonate selective membrane and electrode The carbonate ion selective membrane of the invention comprises (a) a polymeric inert support material; (b) a plasticizer effective to solubilize the support material; (c) a quaternary ammonium ion; (d) an ionophore which is preferentially reactive with c... | 03/07/1989 |
