Assignee: Takeda Chemical Industries, Ltd.

Location: JP
No. of patents: 28

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Number	Title	Issue Date
7070975	Protein and DNA thereof The present invention relates to a novel protein belonging to an ADAM family, a partial peptide thereof or a salt thereof, a DNA encoding the protein, a recombinant vector comprising the DNA, a transformant, a method for producing the protein, a medicine comprising ...	07/04/2006
6399316	PACAP receptor protein, method for preparing said protein, and use thereof This invention discloses a PACAP receptor protein or a salt thereof, a DNA comprising a DNA fragment coding for the protein, a method for preparing the protein, antibody against the protein, and use of the protein, DNA, and antibodies. A PACAP receptor pr...	06/04/2002
5902885	Production of L-ascorbic acid L-ascorbic acid is produced by allowing an acid to act on 2-keto-L-gulonic acid in a mixture solvent of an inert organic solvent and an aliphatic ketone in the presence of water and a surfactant. The method produces L-ascorbic acid in a high yield 90% or more ...	05/11/1999
5829066	Deodorizing apparatus and a toilet provided with the apparatus The deodorizing apparatus includes a gas duct having a suction port to be disposed within a toilet bowl and an exhaust port to be disposed outside the toilet bowl, and an active carbon honeycomb and a chemical-supporting honeycomb as disposed within the g...	11/03/1998
5807869	Quinoline derivatives, their production and use The present quinoline derivatives and compositions having gonadotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormon...	09/15/1998
5698586	Angiogenesis inhibitory agent O-substituted fumagillol derivatives and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization....	12/16/1997
5538947	Growth inhibitory factor Disclosed is a non-naturally-occurring polypeptide having neural growth inhibitory action which has an amino acid sequence represented by the formula: Thr Cys Pro Cys Pro Ser Gly Gly Ser Cys Thr Cys Ala Asp Ser Cys Lys Cys Glu. The polypeptide of the pres...	07/23/1996
5489514	DNA coding for growth-inhibitory factor and use thereof A novel protein of GIF having growth-inhibitory action, which is present in the brain of normal subjects but absent in the brain of patients with Alzheimer disease, was cloned from a human-cerebral cDNA library and human genomic DNA library. Further, Esch...	02/06/1996
5474924	Method for producing 2-keto-L-gulonic acid 2-keto-L-gulonic acid is in high yield produced by contacting a microorganism of the genus Pseudogluconobacter, either as it is or after processing, with L-sorbose....	12/12/1995
5457138	Method for producing open cell rigid polyurethane foam A method of producing an open cell rigid polyurethane foam which comprises reacting a polymethylene polyphenylisocyanate prepolymer with a polyol at an NCO/OH equivalent ratio of 1.3 to 3.0 by use of a blowing agent substantially comprising water in the p...	10/10/1995
5405861	Triazole compounds and antifungal compositions thereof The novel 2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-propanol derivertives of the formula (I): ##STR1## wherein, R0, R1 and R2 are the same or different and represent a hydrogen atom or a lower alkyl group; A ...	04/11/1995
5376681	Aminocoumaran derivatives, their production and use A novel aminocoumaran derivatives of the general formula (I): ##STR1## wherein R1 and R2 are a hydrogen atom, an acyl group, an alkoxycarbonyl group, an aliphatic group or aromatic group; R3 R4 and R5	12/27/1994
5376647	bisphosphonic acid derivatives, and useful as a bone resorption inhibitor A bisphosphonic acid derivative of the general formula (I): ##STR1## wherein A is an optionally substituted cyclic group; R1 is hydrogen atom or a lower alkanoyl group; R2, R3, R4 and R5 are the ...	12/27/1994
5371101	Azole compounds, their production and use An azole compound represented by the formula (I): ##STR1## wherein Ar is a substituted phenyl group; R1 and R2 independently are a hydrogen atom or a lower alkyl group, or R1 and R2 may combine together to form ...	12/06/1994
5371100	Optically active tetrazole compounds, and fungicidal compositions thereof An optically active azole compound of the formula (I): ##STR1## wherein R1 and R2 are independently a hydrogen atom, a halogen atom, a haloalkyl group, a haloalkoxy group or an optionally substituted nitrogen-containing heterocy...	12/06/1994
5371098	Use of oxazole compounds to treat osteoporosis An oxazole compound having the formula (I): ##STR1## in which A is a group of the formula --CH2 OR2 (wherein R2 is a hydrogen atom, an optionally substituted hydrocarbon residue, an optionally substituted heterocyclic...	12/06/1994
5370821	Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions The invention relates to optically active compounds represented by the general formula ##STR1## wherein R1, R2, Q1, Q2, Q3, ##STR2## and M are defined as in the specification, methods and in...	12/06/1994
5369104	Pyridazine compounds, their production and use Novel compound represented by the formula: ##STR1## wherein X stands for a methine (i.e. the group --CH.dbd.) group or a nitrogen atom; R1 stands for a hydrogen atom, an optionally substituted lower alkyl group or a halogen atom; R2	11/29/1994
5364989	1,1,1-trichloro-2-nitroethane production Methods for the production of 1,1,1-trihalogeno-2-nitroethanes from 1,1-dihalogenoethylene by using nitric acid or its salt and hydrogen chloride or hydrogen bromide or its salt, and for the production of ଱-unsaturated amines from the 1,1,1-trihalog...	11/15/1994
5362497	Transdermal therapeutic composition When a transdermal therapeutic composition which contains a pharmaceutically effective ingredient, a water-soluble absorption enhancer, a fat-soluble absorption enhancer and a super water-absorbent resin is applied to the skin of mammals, release of the p...	11/08/1994
5362742	Quinoline derivatives, their production and use as ACAT inhibitors A quinoline derivative of the formula (I): ##STR1## wherein each phenyl ring of A and B can have one or more substituents; X is ##STR2## (R1 is a hydrogen atom, a lower alkyl group or a lower alkoxy group) or ##STR3## (...	11/08/1994
5360624	Emulsion-type food Emulsion-type food in which a part or all of the fat components are substituted by a pulverized curdlan gel is disclosed. The food is low-calorie and has desired appearance, mouthfeel and taste....	11/01/1994
5350777	Production and use of open cell rigid polyurethane foam A method of producing an open cell rigid polyurethane foam which comprises reacting a polyol with a polymethylene polyphenyl polyisocyanate prepolymer with a monool exemplified by diethylene glycol monomethyl ether by use of a substitute such as 1,1-dichl...	09/27/1994
5349064	Production of pyrrolopyrimidines There is provided an improved process for producing novel compounds represented by the general formula: ##STR1## wherein the ring A represents a pyrrole ring which may be hydrogenated; X represents an amino, hydroxyl or mercapto group; R1,...	09/20/1994
5296600	Pyrrolopyrimidine derivatives, their production and use A compound of the formula ##STR1## wherein the ring A pyrrole or pyrroline ring, X is an amino group or a hydroxyl group, Y is a hydrogen atom, an amino group or a hydroxyl group, R is a hydrogen atom, a fluorine atom, an alkyl group, an alkenyl grou...	03/22/1994
5175147	Acid-resistant FGF composition and method of treating ulcerating diseases of the gastrointestinal tract This invention describes pharmaceutical compositions and methods of treating ulcerating diseases of the gastrointestinal tract in mammals with an acid-resistant fibroblast growth factor compositions. Also described is the use of acid-resistant fibroblast ...	12/29/1992
5135919	Method and a pharmaceutical composition for the inhibition of angiogenesis Fumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fuma...	08/04/1992
4876251	Tricyclic penam compounds, their production and their use The compounds, having a 4,10-dioxo-3-oxa-7-thia-1-azatricyclo[6,2,0,02,6 ]decane-2-carboxylic acid skeleton as the base structure, their esters and their salts, are useful antibacterial agents....	10/24/1989

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Assignee: Takeda Chemical Industries, Ltd.