Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 5439826 | Method of distinguishing among strips for different assays in an automated instrument A method of distinguishing between strips for different assays in an automated instrument, wherein characteristics to which the instrument is sensitive are selectively introduced in microwells of individual microstrips which are pretreated with a specific... | 08/08/1995 |
| 5432057 | Simultaneous calibration heterogeneous immunoassay An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) comprising ligand and receptor. By providing a first measurement surface capable of specifically b... | 07/11/1995 |
| 5342759 | Simultaneous calibration heterogeneous immunoassay An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) comprising ligand and receptor. By providing a first measurement surface capable of specifically b... | 08/30/1994 |
| 4663278 | Agglutination dependent enzyme channeling immunoassay A novel agglutination assay is provided which brings together through the intermediacy of the binding of specific binding pair members particles which differ by having different members of a signal producing system. The signal producing system is characte... | 05/05/1987 |
| 4540659 | Simultaneous calibration heterogeneous immunoassay An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) comprising ligand and receptor. By providing a first measurement surface capable of specifically b... | 09/10/1985 |
| 4533629 | Simultaneous calibration heterogeneous immunoassay An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) comprising ligand and receptor. By providing a first measurement surface capable of specifically b... | 08/06/1985 |
| 4508892 | Compositions for competitive protein binding assays inhibiting non-specific interference Conjugates of heavy atoms containing analytes or their analogs and fluorescent molecules are covalently bonded to macromolecular supports to minimize the interference of fluorescence during assays, due to non-specific binding of serum proteins to the conj... | 04/02/1985 |
| 4504413 | Acetaminophen analogs, antigens, and antibodies Carbonyl derivatives of acetaminophen are provided for use in homogeneous enzyme immunoassays for acetaminophen. The derivatives are conjugated to antigenic substances for the preparation of antisera specific to acetaminophen, and to enzymes for the prepa... | 03/12/1985 |
| 4501692 | Charge effects in enzyme immunoassays A method for determining a member of a specific binding pair-ligand and receptor (antiligand). Reagents employed include a first modified member which provides an electrical field due to the presence of a plurality of ionic charges and a second modified m... | 02/26/1985 |
| 4489156 | Chloramphenicol derivatives Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used... | 12/18/1984 |
| 4489157 | Chloramphenicol derivatives Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used... | 12/18/1984 |
| 4481136 | Alkyl substituted fluorescent compounds and conjugates Fluorescent antigen conjugates are provided comprising antigens covalantly bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent c... | 11/06/1984 |
| 4447527 | Single test formulations for enzyme immunoassays and method for preparation Reagent mixtures for single test which allow for rapid determination of drugs without sophisticated equipment. Into a single vial as dry powders are combined an enzyme bound ligand reagent, an antiligand reagent (antibody), appropriate substrates, bulking... | 05/08/1984 |
| 4446065 | Phencyclidine compounds and assays for its determination Novel oxime derivatives of phencyclidine are provided as precursors for conjugating proteins, either antigenic for the preparation of antibodies or enzymatic for the preparation of enzyme conjugates, which antibodies and enzyme conjugates find use as reag... | 05/01/1984 |
| 4444880 | Periodate removal of ascorbate interference in dipsticks for immunoassays A solid support "dipstick" immunoassay impregnated with sodium metaperiodate (NaIO4) is described wherein ascorbate interference with an assay having a peroxidase signal producing system is reduced or eliminated.... | 04/24/1984 |
| 4439356 | Unsymmetrical fluorescein derivatives Unsymmetrically substituted 6-hydroxy-3H-xanthen-3-ones for use as fluorescers or quenchers, particularly conjugated to provide reagents in competitive protein binding assays. Substituents are aliphatic groups bonded to an annular carbon atom through carb... | 03/27/1984 |
| 4435504 | Immunochromatographic assay with support having bound "MIP" and second enzyme Chromatographic immunoassay employing a specific binding pair member and a label conjugate which delineates a border whose distance from one end of the chromatograph relates to the amount of analyte present. By combining the label conjugate and sample in ... | 03/06/1984 |
| 4424150 | Acetaminophen analogs, antigens, and antibodies Carbonyl derivatives of acetaminophen are provided for use in homogeneous enzyme immunoassays for acetaminophen. The derivatives are conjugated to antigenic substances for the preparation of antisera specific to acetaminophen, and to enzymes for the prepa... | 01/03/1984 |
| 4423143 | ଲ-D-Galactosidase conjugate for enzyme immunoassays ଲ-D-Galactosidase conjugates for use in homogeneous immunoassays. ଲ-D-Galactosidase is conjugated with analytes and the resulting conjugates are combined with receptors for the analyte and a sample suspected of containing the analyte. The resu... | 12/27/1983 |
| 4409325 | Valproate conjugation using dicarbonyls -substituted derivatives of valproic acid are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immu... | 10/11/1983 |
| 4404278 | Methods and compositions for assaying for the production of 1,4-dihydropyridyl Methods and compositions for assaying for coenzymes having N-substituted 1,4-dihydropyridyl as the active portion of the prosthetic group. The conversion of NAD to NADH is widely measured both for determining NAD-NADH (including the analogs thereof) depen... | 09/13/1983 |
| 4391904 | Test strip kits in immunoassays and compositions therein An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) of immunogens--ligand and receptor. The method has two basic elements: a solid surface to which on... | 07/05/1983 |
| 4376825 | Enzyme amplification compounds for assays for androgens Novel biological assay method for determining the presence of a specific organic material by employing a modified enzyme for amplification. By employing receptors specific for one or a group of materials (hereinafter referred to as "ligands") and binding ... | 03/15/1983 |
| 4374925 | Macromolecular environment control in specific receptor assays Method and compositions are provided for performing protein binding assays involving a homologous pair consisting of ligand and receptor for the ligand. The method employs a label conjugated to a member of said homologous pair and a uniformly dispersed di... | 02/22/1983 |
| 4366241 | Concentrating zone method in heterogeneous immunoassays Method and apparatus are provided for performing immunoassays employing a device comprising a relatively small test zone referred to as an immunosorbing zone, and a relatively large liquid absorbing zone in liquid receiving relationship with said immunoso... | 12/28/1982 |
| 4351760 | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates Fluorescent antigen conjugates are provided comprising antigens covalently bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent c... | 09/28/1982 |
| 4341866 | Antienzyme termination in enzyme immunoassays An improved method is provided for performing an enzyme immunoassay, where the signal producing compound is chemically labile. Particularly, in homogeneous enzyme immunoassays, where the enzyme is conjugated with a hapten, and an antibody binding to hapte... | 07/27/1982 |
| 4329461 | Fluorescent thyroid hormone conjugates and their uses Novel polyhalothyronines or immunogenic mimetic analogs are provided conjugated to a fluorescer compound with the resulting conjugate being highly fluorescent. Specifically, the compounds have at least one of the following characteristics: bromine(s) at t... | 05/11/1982 |
| 4329502 | Propranolol antigen conjugates and antibodies Compounds are provided which can be used in the preparation of reagents useful for quantitatively determining the presence of b-adrenergic blocking agents. These compounds contain a derivative of the blocking agent which is linked to an antigen or enzyme,... | 05/11/1982 |
| 4328311 | Enzyme-aminoglycoside conjugates Methods and compositions are provided for conjugating a wide variety of compounds, particularly polyfunctional compounds, having a mercapto group, either naturally present or synthetically introduced, to a polyamino compound, particularly a polypeptide (i... | 05/04/1982 |
| 4323507 | Valproate conjugation using dicarbonyls -substituted derivatives of valproic acid are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immu... | 04/06/1982 |
| 4318707 | Macromolecular fluorescent quencher particle in specific receptor assays Homogeneous immunoassay employing a light absorbing particle to which a member of an immunological pair (mip)-ligand and antiligand is bound and a labeled mip, where the label is light emitting. The labeled mip becomes bound to the light absorbing particl... | 03/09/1982 |
| 4318846 | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers Diether symmetrically substituted fluoresceins are provided having at least one anionic group and a linking functionality. Depending upon the site of substitution, the compounds can be used as fluorescers absorbing at wavelengths in excess of 500 nm or as... | 03/09/1982 |
| 4307245 | Amitriptyline conjugates to antigenic proteins and enzymes Amitriptyline functionalized compounds are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays f... | 12/22/1981 |
| 4299916 | Preferential signal production on a surface in immunoassays An assay method and compositions are provided for determining the presence of an analyte in a sample. The analyte is a member of an immunological pair (mip) of immunogens--ligand and receptor. The method has two basic elements: a solid surface to which on... | 11/10/1981 |
| 4288553 | Disopyramide compounds for conjugating proteins used in immunoassays for disopyramide Novel carboxyalkylated disopyramides (NORPACE.RTM.) are provided as precursors for conjugating proteins, either antigenic for the preparation of antibodies or enzymatic for the preparation of enzyme conjugates, which antibodies and enzyme conjugates find ... | 09/08/1981 |
| 4287300 | Charge effects in enzyme immunoassays A method for determining a member of a specific binding pair-ligand and receptor (antiligand). Reagents employed include a first modified member which provides an electrical field due to the presence of a plurality of ionic charges and a second modified m... | 09/01/1981 |
| 4282325 | Enzyme bound corticosteroids Novel biological assay method for determining the presence of a specific organic material by employing a modified enzyme for amplification. By employing receptors specific for one or a group of materials (hereinafter referred to as "ligands") and binding ... | 08/04/1981 |
| 4281065 | Phencyclidine conjugates to antigenic proteins and enzymes Phencylidine, PCP, derivatives having a non-oxo carbonyl functionality linked directly or through a linking group to the phenyl ring are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjuga... | 07/28/1981 |
| 4281061 | Double antibody for enhanced sensitivity in immunoassay Method and compositions are provided for performing homogeneous immunoassays. The method involves having a signal producing system, which provides a detectable signal, which system includes a macromolecular member. The determination of the analyte, which ... | 07/28/1981 |
