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| Number | Title | Issue Date |
| 7439056 | Peelable and resealable devices for arraying materials Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the f... | 10/21/2008 |
| 7422651 | Apparatus and method for handling membranes A method for applying a pattern to a target surface includes the steps of applying a coating of membrane material over a selected portion of a substrate. The substrate imparts a pattern to the membrane material corresponding to a pattern to be applied to the target ... | 09/09/2008 |
| 7419823 | Device and method for monitoring leukocyte migration A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. Th... | 09/02/2008 |
| 7374906 | Biological assays using gradients formed in microfluidic systems The present invention discloses a device for monitoring chemotaxis or chemoinvasion. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed ... | 05/20/2008 |
| 7371563 | Peelable and resealable devices for biochemical assays Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the f... | 05/13/2008 |
| 7364899 | Device for monitoring haptotaxis The present invention discloses a device for monitoring haptotaxis including a housing defining a chamber. The chamber comprises: a first well region including at least one first well, the first well configured to receive a test agent therein and further including b... | 04/29/2008 |
| 7351575 | Methods for processing biological materials using peelable and resealable devices Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the f... | 04/01/2008 |
| 7338613 | System and process for automated microcontact printing An automated process for microcontact printing is provided, comprising the steps of providing a substrate and a stamp; automatically aligning the substrate and stamp so that the stamp is aligned relative to the substrate to impart a pattern to the substrate at a des... | 03/04/2008 |
| 7326563 | Device and method for monitoring leukocyte migration A device for monitoring leukocyte migration is provided. The device generally includes a plurality of chambers, each chamber including a channel in which leukocyte migration mediators or endothelial cells are disposed therein. The device is fabricated in the footpri... | 02/05/2008 |
| 7285412 | Device for magnetic immobilization of cells The present invention relates to an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate on which are located one or more magnetic receptacle(s). Alternatively, in another aspect the present invention, the device a... | 10/23/2007 |
| 7244598 | Biomolecule arrays Array systems that facilitate the simultaneous monitoring of many interactions between biological molecules and the analysis of cellular protein interactions with high throughput. The present invention provides methods and arrays for analyzing biochemical pathways b... | 07/17/2007 |
| 7211209 | Method of making device for arraying biomolecules and for monitoring cell motility in real-time The invention relates to devices, devices for arraying biomolecules, including cells, methods for arraying biomolecules, assays for monitoring cellular movement, and systems for monitoring cellular movement. The devices include a support; a first layer configured to... | 05/01/2007 |
| 7123764 | Image processing method for use in analyzing data of a chemotaxis or haptotaxis assay An image processing method for use in analyzing image data of a cellular migration assay. The method includes defining a major axis within the image data that is perpendicular to an orientation of channels in the image data, determining an aggregate light intensity ... | 10/17/2006 |
| 6937804 | Non-linear photonic switch and method of making the same A photonic switch according to the present invention may be formed using one of a selected group of non-linear optical materials. Each of the materials within this group has a refractive index that demonstrates a substantial peak as a function of wavelength, where t... | 08/30/2005 |
| 6885790 | Non-linear photonic switch A photonic switch may be formed using one of a selected group of non-linear optical materials. Each of the materials within this group has a refractive index that demonstrates a substantial peak as a function of wavelength. The photonic switch includes a positive ga... | 04/26/2005 |
| 6833040 | Apparatus and method for handling membranes A method for applying a pattern to a target surface includes the steps of applying a coating of membrane material over a selected portion of a substrate. The substrate imparts a pattern to the membrane material corresponding to a pattern to be applied to the target ... | 12/21/2004 |
| 6811968 | Method of monitoring cell motility and chemotaxis The present invention discloses a method of monitoring chemotaxis or chemoinvasion comprising: providing a device for monitoring chemotaxis. The device includes a support member; a top member mounted to the support member by being placed in substantially fluid-tight... | 11/02/2004 |
