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| Number | Title | Issue Date |
| 7422889 | Dre recombinase and recombinase systems employing Dre recombinase The invention provides a Dre/rox recombinase system. In particular, the invention provides Dre polypeptides that can catalyze site-specific recombination at rox sites but not at lox sites. The Dre/rox system can be utilized in a number of genetic manipulations eithe... | 09/09/2008 |
| 7285699 | Ends-out gene targeting method A gene targeting method for use in a host organism whereby the host organism is transfected with an ends-out donor construct. Further transfecting the host organism with two transgenes expressing endonuclease and recombinase enzymes. The endonuclease and recombinase... | 10/23/2007 |
| 6160095 | Proteins capable of regulating NF-.kappa.B, JNK and apoptosis pathways and methods of using the same Testing methods are provided for determining whether given candidate compounds are effective for regulating NF-.kappa.B, JNK and apoptosis cell activities. The methods involve forming a mixture including a compound such as a proteinaceous specie containin... | 12/12/2000 |