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| Number | Title | Issue Date |
| 7750013 | N-oxides as prodrugs of piperazine and piperidine derivatives The present disclosure relates to N-oxides of certain piperazine and piperidine derivatives and to methods for the preparation of these compounds. The disclosure also relates to the use of the compounds for the manufacture of a medicament giving a beneficial effect.... | 07/06/2010 |
| 7596407 | Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds The invention is related to an iontophoretic method for the delivery of a compound of the formula wherein R is defined herein, and pharmaceutically acceptable salts and prodrugs thereof; and, ... | 09/29/2009 |
| 7595310 | Glucuronate salt of a piperazine compound The present invention provides a salt form, and compositions thereof, useful as a modulator of one or more GPCRs and which exhibits desirable characteristics for the same. The present invention also provides methods for preparing said salt form. ... | 09/29/2009 |
| 7528162 | 4,5-dihydro-1H-pyrazole derivatives having CB-antagonistic activity The present invention relates to a group of novel 4,5-dihydro-1H-pyrazole derivatives which are potent cannabinoid (CB1) receptor antagonists with utility for the treatment of diseases connected with disorders of the cannabinoid system. The compounds have... | 05/05/2009 |
| 7524867 | Tetrasubstituted imidazole derivatives as cannabinoid CB receptor modulators with a high CB/CBreceptor subtype selectivity The present invention relates to 1,2,4,5-tetrasubstituted imidazole derivatives as selective cannabinoid CB1 receptor modulators, in particular CB1 receptor antagonists or inverse agonists having a high CB1/CB2 receptor su... | 04/28/2009 |
